A5003661435- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Visual perception and processing mechanisms
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Psychology of Moral and Emotional Judgment
- Face Recognition and Perception
- Mental Health Research Topics
- Decision-Making and Behavioral Economics
- Multisensory perception and integration
- Consumer Behavior in Brand Consumption and Identification
- Experimental Behavioral Economics Studies
- Behavioral Health and Interventions
- Music Therapy and Health
- Memory and Neural Mechanisms
- Blind Source Separation Techniques
- Neuroscience and Music Perception
- Evolutionary Game Theory and Cooperation
- Olfactory and Sensory Function Studies
- Action Observation and Synchronization
- Gait Recognition and Analysis
- Transcranial Magnetic Stimulation Studies
- Neurotransmitter Receptor Influence on Behavior
- Tactile and Sensory Interactions
- Evolutionary Psychology and Human Behavior
University of Glasgow
2015-2024
NHS Lanarkshire
2024
Wellcome Centre for Human Neuroimaging
2023-2024
University of Nottingham
2013
Max Planck Institute for Human Development
2007-2011
Freie Universität Berlin
2011
Max Planck Institute for Human Cognitive and Brain Sciences
2010-2011
Max Planck Society
2007-2010
Columbia University
2004-2007
Howard Hughes Medical Institute
2004
When does the brain know that a decision is difficult to make? How difficulty affect allocation of neural resources and timing constituent cortical processing? Here, we use single-trial analysis electroencephalography (EEG) identify correlates relate these accuracy. Using cued paradigm, show can component in EEG reflects inherent task not simply correlation with stimulus. We find this arises approximately 220 ms after stimulus presentation, between two components are predictive accuracy [an...
The superior colliculus (SC) is part of a network brain areas that directs saccadic eye movements, overtly shifting both gaze and attention from position to position, in space. Here, we seek direct evidence the SC also contributes control covert spatial attention, process focuses on region space different point gaze. While requiring monkeys keep their fixed, tested whether microstimulation specific location map would enhance visual performance at corresponding space, diagnostic measure...
Single and multi-unit recordings in primates have identified spatially localized neuronal activity correlating with an animal's behavioral performance. Due to the invasive nature of these experiments, it has been difficult identify such correlates humans. We report first non-invasive neural measurements perceptual decision making, via single-trial EEG analysis, that lead neurometric functions predictive psychophysical performance for a face versus car categorization task. two major...
A fundamental feature of how we make decisions is that our responses are variable in the choices and time it takes to them. This makes impossible determine, for a single trial an experiment, quality evidence on which decision based. Even stimuli from experimental condition, likely stimulus encoding differences lead evidence. In research reported here, with simple “face”/“car” perceptual discrimination task, obtained late (decision-related) early (stimulus-related) single-trial EEG component...
Current computational accounts posit that, in simple binary choices, humans accumulate evidence favour of the different alternatives before committing to a decision. Neural correlates this accumulating activity have been found during perceptual decisions parietal and prefrontal cortex; however source such value-based choices remains unknown. Here we use simultaneous EEG-fMRI modelling identify EEG signals reflecting an accumulation process demonstrate that within- across-trial variability...
Single-unit and multiunit recordings in primates have already established that decision making involves at least two general stages of neural processing: representation evidence from early sensory areas accumulation to a threshold decision-related regions. However, the relay information areas, such process is instigated, not well understood. Using cued paradigm single-trial analysis electroencephalography (EEG), we previously reported on temporally specific components related perceptual...
To make decisions based on the value of different options, we often have to combine sources probabilistic evidence. For example, when shopping for strawberries a fruit stand, one uses their color and size infer—with some uncertainty—which taste best. Despite much progress in understanding neural underpinnings value-based decision making humans, it remains unclear how brain represents evidence they are used compute signals needed drive decision. Here, use visual categorization task show that...
Single-unit animal studies have consistently reported decision-related activity mirroring a process of temporal accumulation sensory evidence to fixed internal decision boundary. To date, our understanding how response patterns seen in single-unit data manifest themselves at the macroscopic level brain obtained from human neuroimaging remains limited. Here, we use single-trial analysis electroencephalography show that population responses on scalp can capture choice-predictive builds up...
The extent to which different cognitive processes are "embodied" is widely debated. Previous studies have implicated sensorimotor regions such as lateral intraparietal (LIP) area in perceptual decision making. This has led the view that decisions embodied same networks guide body movements. We use event-related fMRI and effective connectivity analysis investigate whether human system implements decisions. show when eye hand motor preparation disentangled from decisions, areas not involved...
Choice confidence, an individual's internal estimate of judgment accuracy, plays a critical role in adaptive behaviour, yet its neural representations during decision formation remain underexplored. Here, we recorded simultaneous EEG-fMRI while participants performed direction discrimination task and rated their confidence on each trial. Using multivariate single-trial discriminant analysis the EEG, identified stimulus-independent component encoding which appeared prior to subjects' explicit...
This review summarizes linear spatiotemporal signal analysis methods that derive their power from careful consideration of spatial and temporal features skull surface potentials. BCIs offer tremendous potential for improving the quality life those with severe neurological disabilities. At same time, it is now possible to use noninvasive systems improve performance time-demanding tasks. Signal processing machine learning are playing a fundamental role in enabling applications BCI many...
Avoiding repeated mistakes and learning to reinforce rewarding decisions is critical for human survival adaptive actions. Yet, the neural underpinnings of value systems that encode different decision-outcomes remain elusive. Here coupling single-trial electroencephalography with simultaneously acquired functional magnetic resonance imaging, we uncover spatiotemporal dynamics two separate but interacting encoding decision-outcomes. Consistent a role in regulating alertness switching...
Branding has become one of the most important determinants consumer choices. Intriguingly, psychological mechanisms how branding influences decision making remain elusive. In research reported here, we used a preference-based decision-making task and computational modeling to identify which internal components processing are affected by branding. We found that process noisy temporal integration subjective value information can model choices reliably biases explained changes in rate itself....
Reward learning depends on accurate reward associations with potential choices. These can be attained reinforcement mechanisms using a prediction error (RPE) signal (the difference between actual and expected rewards) for updating future expectations. Despite an extensive body of literature the influence RPE learning, little has been done to investigate potentially separate contributions valence (positive or negative) surprise (absolute degree deviation from expectations). Here, we coupled...
Abstract Despite recent progress in understanding multisensory decision-making, a conclusive mechanistic account of how the brain translates relevant evidence into decision is lacking. Specifically, it remains unclear whether perceptual improvements during rapid decisions are best explained by sensory (i.e., ‘Early’) processing benefits or post-sensory ‘Late’) changes dynamics. Here, we employ well-established visual object categorisation task which early and can be dissociated using...
Abstract Metacognitive evaluations of confidence provide an estimate decision accuracy that could guide learning in the absence explicit feedback. We examine how humans might learn from this implicit feedback direct comparison with feedback, using simultaneous EEG-fMRI. Participants performed a motion direction discrimination task where stimulus difficulty was increased to maintain performance, intermixed explicit- and no-feedback trials. isolate single-trial estimates post-decision EEG...
Sensory discriminations, such as judgements about visual motion, often benefit from multisensory evidence. Despite many reports of enhanced brain activity during conditions, it remains unclear which dynamic processes implement the for an upcoming decision in human brain. Specifically, difficult to attribute perceptual benefits specific processes, early sensory encoding, transformation representations into a motor response, or more unspecific attention. We combined audio-visual motion...
fMRI activity encoding acquisition and processing of feedback enables discrimination response to self-help CBT in depression.