A5100685120- Neuroscience and Neural Engineering
- Transcranial Magnetic Stimulation Studies
- EEG and Brain-Computer Interfaces
- Vagus Nerve Stimulation Research
- Urinary Bladder and Prostate Research
- Wireless Power Transfer Systems
- Pelvic floor disorders treatments
- Advanced Sensor and Energy Harvesting Materials
- Muscle activation and electromyography studies
- Heart Rate Variability and Autonomic Control
- Urological Disorders and Treatments
- Neural dynamics and brain function
- Orthopedic Surgery and Rehabilitation
- Conducting polymers and applications
- PARP inhibition in cancer therapy
- Advanced Image Fusion Techniques
- Diatoms and Algae Research
- Microfluidic and Bio-sensing Technologies
- Laser Material Processing Techniques
- Advanced Neural Network Applications
- Urologic and reproductive health conditions
- Visual Attention and Saliency Detection
- Optical Coherence Tomography Applications
- Spine and Intervertebral Disc Pathology
- Phytochemical Studies and Bioactivities
Pohang University of Science and Technology
2020-2025
Pukyong National University
2023
Kangwon National University
2022
Korea Post
2020
Korea University Medical Center
2014
Korea Institute of Ceramic Engineering and Technology
2014
Korea University
2014
Seoul National University
2005
A critical problem with stretchable supercapacitors developed to date has been evaporation of a volatile component their electrolyte, causing failure. In this work, we demonstrated successful use an ionic-liquid-based nonvolatile gel (ion–gel) electrolyte in carbon nanotube (CNT)-based supercapacitors. The CNT/ion–gel showed high capacitance retention (96.6%) over 3000 stretch cycles at 20% strain. durability against was achieved by introducing microroughness the interfaces between different...
Abstract In implantable bioelectronics, which aim for semipermanent use of devices, biosafe energy sources and packaging materials to protect devices are essential elements. However, research so far has been conducted in a direction where they cannot coexist. Here, the development capacitance‐matched triboelectric implants driven is reported by ultrasound under 500 mW cm −2 safe intensity realize battery‐free, miniatured, wireless neurostimulator with full titanium (Ti) packaging. The...
Direct electrical stimulation of the seizure focus can achieve early termination epileptic oscillations. However, direct intervention hippocampus, most prevalent in temporal lobe epilepsy is thought to be not practicable due its large size and elongated shape. Here, a rat model, we report sequential narrow-field method for terminating seizures, while focusing stimulus energy at spatially extensive hippocampal structure. The effects regional specificity this were demonstrated via...
Tibial nerve stimulation (TNS) is one of the neuromodulation methods used to treat an overactive bladder (OAB). However, treatment mechanism not accurately understood owing significant differences in results obtained from animal and clinical studies. Thus, this study was aimed confirm response activity different frequencies observe duration prolonged post-stimulation inhibitory effects following TNS. This unanesthetized rats provide a closer approximation setting evaluated changes 30 min TNS...
Neural interfaces play a major role in modulating neural signals for therapeutic purposes. To meet the demand of conformable developing bioelectronic medicine, recent studies have focused on performance electrical neurostimulators employing soft conductors such as conducting polymers and electronic or ionic conductive hydrogels. However, faradaic charge injection at interface electrode nerve tissue causes irreversible gas evolution, oxidation electrodes, reduction biological ions, thus...
The present study aimed to evaluate a new tibial nerve stimulation (TNS) modality, which uses interferential currents, in terms of the electric field penetration efficiency into body and physiological effectiveness.In silico experiments were performed analyze proposed current therapy (ICT). Based on this, we vivo measure excitation threshold ICT for nerve, is related near nerve. Regarding analysis effectiveness, ICT-TNS was performed, changes bladder contraction frequency voiding volume...
Transcranial electrical stimulation (TES) is a widely accepted neuromodulation modality for treating brain disorders. However, its clinical efficacy fundamentally limited due to the current shunting effect of scalp and safety issues. A newer technique called subcutaneous (SES) promises overcome limitations TES by applying currents directly at site disorder through skull. While SES seems promising, electrophysiological compared still unknown, thus limiting broader application. Here we...
This work reports the high-efficient and one-step immobilization of multimeric protein G on magnetic nanoparticles. The histidine-tagged (His-tag) recombinant was overexpressed in Escherichia coli BL21 by repeated linking monomers with a flexible linker. High-efficient nanoparticles demonstrated two different preparation methods through amino-silane chloro-silane functionalization silica-coated Three kinds such as His-tag monomer, dimer, trimer were tested for efficiency. For these tests,...
Objective. Auricular vagus nerve stimulation (aVNS) has recently emerged as a promising neuromodulation modality for blood pressure (BP) reduction due to its ease of use although efficacy is still limited compared direct baroreflex stimulation. Previous studies have also indicated that synaptic depression nucleus tractus solitarius (NTS) in the pathway depends on stimulus frequency. However, nature this frequency dependence phenomenon antihypertensive effect been unknown aVNS. We aimed...
In this paper, we developed a miniaturized Wireless Power Transfer (WPT) based implantable stimulator that can deliver electrical energy directly to peripheral nerves using electromagnetic induction between internal and external coils. The WPT system was designed reduce the sensitivity of alignment increase efficiency considering properties human body tissues devices. received signals at receiving coil are rectified by rectifying circuit harvested in capacitor turn on pulse generating...
Abstract Background This study presents a novel technique to develop an equivalent circuit model (ECM) for analyzing the responses of layered body structure transcutaneous electrical nerve stimulation (TENS) by parameterizing and geometrical properties.Many classical ECMs are non-parametric because difficulty in projecting intrapersonal variability physical properties into ECM. However, not considering hampers patient-specifically response TENS personal optimization parameter design. To...
The tarsal tunnel is located beneath the flexor retinaculum, which connects medial malleolus and calacaneus. contains posterior tibialis tendon, digitorum longus tibial artery vein, nerve, halluces tendon. Tarsal syndrome a compressive neuropathy of nerve its branches under retinaculum. etiologies are space-occupying lesion, hypertrophied osteophytes, coalition, varicose trauma. symptoms foot pain hypoesthesia or paresthesia at dermatome according to involving branches. Clinical diagnosis...
Compared to the existing noninvasive methods, temporal interference (TI) current stimulation is an emerging neuromodulation technique that can improve ability focus electrical field on a target nerve. Induced TI distribution depends anatomical structure of individual neurons, and thus electrode optimization enhance must reflect these factors. The study presents framework for focusing energy tibial nerve through extensive simulations, factoring in differences. We conducted large-scale...
Abstract The brainstem serves as an intermediary processor of haemodynamic sensations via nucleus tractus solitaries (NTS) in regulating circulatory system. After sensing visceral inputs, the NTS relays information to efferent pathways modulate peripheral viscera. However, neural computation mechanism underlying how processes viscerosensory input remains unknown. Here, we show computational principles embedded inside rats, producing modulation concert. Our findings demonstrate that...
Synthesis of the functionalized silica-coated magnetic nanoparticles (Si-MNPs) was achieved with organic/inorganic hybrids and approached for high throughput biomolecular separation. To increase reactivity between biomolecules Si-MNPs, organic/ inorganic hybrid functionalization has been obtained through coupling organosilanes, having various organic residues, free sianol groups silica surfaces. This review gives an overview preparation, properties, current applications materials in areas...
Segmental C1-2 screw fixation using C1 lateral mass screws and C2 pedicle is a technically demanding procedure which can cause injuries to the vertebral artery or neural structures as well massive bleeding from epidural venous plexus. In particular, this more difficult in revision cases because of lack normal anatomical landmarks, adhesion, bleeding. The authors report case patient whom preoperative surgical simulation planning computer software was very helpful direct screwing atlas axis...
Laser skin treatment using micro-lens arrays (MLA) and diffractive optical elements (DOE) have clinically been applied to treat pigmented lesions [1,2]. However, DOE hardly has a deep penetration depth MLA shows non-uniform distribution of lesions, making it difficult target deeply located in the dermis [2]. The purpose this study is investigate feasibility lens (DLA, combination DOE) via laser-induced thermal decomposition at various tissue depth. Porcine one farm pig were used compare...
Urethral stenosis is a narrowing of the urethra caused by inflammation, or surgical trauma. Although endoscopic managements have been applied for short stricture, high recurrence rates and complications still remained. Recently, balloon-assisted cylindrical laser ablation using diffusing applicator (DA) has investigated to treat tubular tissue [1,2]. Even though previous studies confirmed safety efficacy [1,2], performance validation unmet clinical situations. This study aims establish...