A5079871201- Bone Tissue Engineering Materials
- Viral Infections and Immunology Research
- Viral gastroenteritis research and epidemiology
- Enterobacteriaceae and Cronobacter Research
- Bacteriophages and microbial interactions
- Listeria monocytogenes in Food Safety
- Vibrio bacteria research studies
- Animal Virus Infections Studies
- 3D Printing in Biomedical Research
- Salmonella and Campylobacter epidemiology
- RNA and protein synthesis mechanisms
- Parasitic Infections and Diagnostics
- Hepatitis C virus research
- Microbial Metabolism and Applications
- Probiotics and Fermented Foods
- Hydrogels: synthesis, properties, applications
- Plant Pathogenic Bacteria Studies
- Antimicrobial Resistance in Staphylococcus
- Plant Virus Research Studies
- Essential Oils and Antimicrobial Activity
- Pediatric health and respiratory diseases
- Animal Disease Management and Epidemiology
- Synthesis and Biological Evaluation
- Hepatitis B Virus Studies
- HIV Research and Treatment
Chang Gung Memorial Hospital
2024-2025
Chengdu University
2023-2025
Chinese Academy of Sciences
2025
University of Chinese Academy of Sciences
2025
Chengdu Organic Chemicals (China)
2025
Markey Cancer Center
2025
University of Kentucky
2025
University of Shanghai for Science and Technology
2021-2024
Shanghai University of Medicine and Health Sciences
2024
Wuhan Polytechnic University
2023-2024
This study was to estimate the prevalence and characteristics of Staphylococcus aureus from 1,850 retail meat products in China during July 2011 June 2016. The samples were collected covering most provincial capitals China, including 604 raw meat, 601 quick-frozen 645 ready-to-eat meat. Using qualitative quantitative methods, all 39 cities had S. aureus-positive samples, detected 35.0% (647/1,850) samples. levels showed that MPN value majority positive ranged 0.3 100 MPN/g. Twenty-four...
Abstract Infected bone defects are one of the most challenging problems in treatment due to high antibiotic failure rate and lack ideal grafts. In this paper, inspired by clinical cement filling treatment, α ‐c phosphate ( ‐TCP) with self‐curing properties is composited β ‐tricalcium constructed a bionic cancellous scaffolding system α/β‐tricalcium / low‐temperature 3D printing, gelatin preserved inside scaffolds as an organic phase, later loaded metal–polyphenol network structure tea...
Objective: Early reports have indicated that the Omicron variant of coronavirus disease 2019 (COVID-19) may be associated with low mortality. However, mortality rate critical patients in Taiwan COVID-19 caused by different variants has not been well described. Methods: This retrospective cohort study was conducted at Linkou Branch Chang Gung Memorial Hospital, Taiwan, from April 2020 to September 2022. Critically ill who had confirmed SARS-CoV-2 infection and were on mechanical ventilation...
Bacillus cereus is a common and important food-borne pathogen that can be found in various food products. Due to low-temperature sterilization for short period of time, pasteurization not sufficient complete elimination B. milk, thereby cause severe economic loss safety problems. It therefore paramount importance perform risk assessment pasteurized milk. In this study, we isolated from milk samples different regions China, evaluated the contamination situation, existence virulence genes,...
Staphylococcus aureus is one of the most important food-borne pathogens globally. It produces various toxins and invasive enzymes can be found in numerous food products. Milk an source staphylococcal poisoning. After pasteurization, this microorganism or its enterotoxins might still remain pasteurized milk. Therefore, study was to investigate contamination S. 258 milk from 39 cities China. The prevalence levels these samples as well antibiotic susceptibility profiles, virulence genes,...
Increasing data indicate that insects serve as major reservoirs and vectors of viruses, which account for the continuously increasing ecological burden infectious disease outbreaks. Uncovering hidden diversity viruses in will further understanding evolutionary perspectives emergence insect-associated virus diseases. In this study, we queried transcriptome sequencing (RNA-Seq) from more than 600 species across 32 insect orders dwelling different habitats recovered 1,213 RNA were recapitulated...
Salmonella remains the leading cause of reported bacterial foodborne disease in China. Meat products obtained from livestock are recognized as one major sources human salmonellosis; however, there is a lack comprehensive, quantitative data concerning contamination these foods. Therefore, objectives this study were to investigate prevalence, load, and antimicrobial resistance profiles various serovars retail meat across whole Between July 2011 June 2016, total 807 product samples collected 39...
Listeria monocytogenes is a globally notoriousfoodborne pathogen. This study aimed to qualitatively and quantitatively detect L. from meat products in China establish their virulence profiles population diversity. From 1212 product samples, 362 (29.9%) were positive for monocytogenes. Serogroup analysis showed that the most prevalent serogroup of was I.1 (1/2a-3a), which accounted 45.0% (123/458) total, followed by I.2 (1/2c-3c) comprised 26.9%, II.1 (4b-4d-4e) 4.8%, II.2 (1/2b-3b-7) 23.3%....
Vibrio parahaemolyticus is a marine and estuarine bacterium that leads to damage of aquatic industry by foodborne outbreaks possesses an enormous threat food safety as well human health worldwide. In the current study, we investigated 905 samples (ready-to-eat foods, fish, shrimp) from 15 provinces in China, aimed determine prevalence, biological characteristics genetic diversity presumptive V. isolates. Firstly, 14.17% 240 fish samples, 15.34% 365 shrimp 3.67% 300 RTE were positive for...
Cronobacter spp. are foodborne pathogens that can infect and cause life-threatening diseases in all age groups, particularly infants immunocompromised elderly. This study aimed to investigate the prevalence, antibiotic susceptibility, molecular characteristics of isolates edible mushrooms collected from 44 cities China. In total, 668 were traditional retail markets supermarkets analyzed by quantitative methods, PCR-based serotyping, multilocus sequence typing (MLST), susceptibility testing....
Listeria monocytogenes is a foodborne pathogen with high mortality rate in humans. This study aimed to identify the pathogenic potential of L. isolated from ready-to-eat (RTE) foods and pasteurized milk China on basis its phenotypic genotypic characteristics. Approximately 7.7% (44/570) samples tested positive for among 10.8% (39/360) RTE 2.4% (5/210) samples, which 77.3% (34/44) had 110 MPN/g. A total 48 strains (43 five samples) were 44 samples. PCR-serogroup analysis revealed that most...
The electron-rich Ru sites are isolated in body-centered cubic RuGa intermetallic compounds, which reduces the energy barrier of rate-limiting step HER process, thus promoting high-current-density activity.
A series of non-nucleoside reverse transcriptase inhibitors derived from indole-based α-amino acids were designed and synthesized. Their inhibitory activities detected by a TZM-bl cell assay on HIV virus type HIV-1IIIB. The comprehensive understanding the SAR was obtained utilizing variation substituents acids. From screened compounds, novel 19 29 identified to be highly potent candidates with EC50 values 0.060 μM 0.045 respectively (CC50 109.545 49.295 SI 1825.8 1095.4). In most cases, at...
Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is a multifactorial characterized by hepatic steatosis. Mitochondrial dysfunction resulting in the incomplete digestion of surplus fat one key factors that lead to steatosis but reason for this remains unclear. We investigated role neurotensin (NTS), gut hormone, inducing maladaptive metabolism liver. identify CD36 and PGC1α, two critical drivers MASLD, as direct NTS signaling targets upregulates CD36, free fatty acid...
Human norovirus is regarded as the leading cause of nonbacterial acute diarrhea in developing and developed countries. Among all genotypes, GII.4 has been predominant genotype, but East Asia, it was replaced by GII.17 2014/2015. However, after prevalence new variant South China, a sharply increase number infections associated with sporadic detected. In this study, we would investigate genetic diversity noroviruses gastroenteritis cases post-GII.17 period China.Norovirus screened from 217...
Sequence type 59 (ST59) is a predominant clonal lineage of community-acquired, methicillin-resistant Staphylococcus aureus (CA-MRSA) in Asia. Despite its increasing clinical relevance China, the evolution and geographic expansion ST59 has been relatively uncared for. Previous study shown that was clone food-related MRSA China. This compared genomes 87 complex (CC) S. isolates sourced from food chain infection cases to reconstruct molecular geographical spread ST59. Accordingly, three major...