A5103059490- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Bacillus and Francisella bacterial research
- Immune Response and Inflammation
- Bacteriophages and microbial interactions
- Plant Growth Enhancement Techniques
- Ferroptosis and cancer prognosis
- PI3K/AKT/mTOR signaling in cancer
- Microplastics and Plastic Pollution
- Plant Molecular Biology Research
- Phytochemistry and Biological Activities
- Probiotics and Fermented Foods
- Plant Disease Resistance and Genetics
- Natural product bioactivities and synthesis
- Aquaculture disease management and microbiota
- Phytochemical Studies and Bioactivities
- Environmental Chemistry and Analysis
- Growth and nutrition in plants
- Phytoplasmas and Hemiptera pathogens
- Polymer-Based Agricultural Enhancements
- Blood properties and coagulation
- Insect-Plant Interactions and Control
- Helicobacter pylori-related gastroenterology studies
- Diverse Scientific Research in Ukraine
Institute of Microbiology
2018-2025
Shanghai Eighth People Hospital
2025
Shandong Provincial Hospital
2021-2025
Shandong First Medical University
2021-2025
Anhui Medical University
2024
Dali University
2024
Second Hospital of Anhui Medical University
2024
South China Agricultural University
2023-2024
Xi'an Jiaotong University
2019-2023
First Affiliated Hospital of Xi'an Jiaotong University
2023
Bacillus cereus is a common and important food-borne pathogen that can be found in various food products. Due to low-temperature sterilization for short period of time, pasteurization not sufficient complete elimination B. milk, thereby cause severe economic loss safety problems. It therefore paramount importance perform risk assessment pasteurized milk. In this study, we isolated from milk samples different regions China, evaluated the contamination situation, existence virulence genes,...
Exercise training (ExT) is beneficial for cardiovascular health, yet the central mechanism by which aerobic ExT attenuates hypertensive responses remains unclear. Activation of pro-inflammatory cytokines (PICs) in hypothalamic paraventricular nucleus (PVN) important sympathoexcitation and response. We thus hypothesized that can decrease blood pressure rats reducing levels PICs through TLR4/MyD88/NF-κB signaling within PVN. To examine this hypothesis, two-kidney-one-clip (2K1C) renovascular...
Abstract Rice husk, an agricultural waste from the rice industry, can cause serious environmental pollution if not properly managed. However, husk ash (RHA) has been found to have many positive properties, making it a potential replacement for non-renewable peat in soilless planting. Thus, this study investigated impact of RHA composite substrate on growth, photosynthetic parameters, and fruit quality cucumber (Yuyi longxiang variety) melon (Yutian yangjiaomi variety). The RHA, peat,...
Abstract Background Mounting evidences have displayed that the dysregulation of miRNAs plays important roles in pathogenesis gastric cancer (GC). The purpose this study was to explore biological functions and potential mechanism miR-489 GC progression. Methods Quantitative real-time PCR (qRT-PCR) western blot were performed examine mRNA expression protein levels HDAC7. relationship between HDAC7 analyzed by Spearman rank correlation. 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium...
Gastric cancer (GC) is a huge threat to global health, there no effective treatment or just delay the progression of advanced GC until now. Micro-RNAs were reported participate in GC. Clonal formation, MTT, caspase-3 activity, sperm DNA fragmentation, flow cytometry assay, cell adhesion, transwell assays performed detect functions miR-32-5p anti-miR-32-5p on growth and metastasis cells. Western blot, qRT-PCR, Co-immunoprecipitation, luciferase reporter analysis explore associated mechanisms....
Lactobacillus fermentum 9-4 is a purine-degrading probiotic firstly isolated from traditional fermented rice-flour noodles with special characteristics of southern China's Guangxi Zhuang Autonomous Region. L. could efficiently reduce the purine contents in foods excellent purine-nucleoside assimilation and purine-metabolizing enzymatic activities. Crude cell lysate showed strong degradation abilities on nucleosides including inosine, guanosine, purines xanthine uric acid, indicating complete...
Thyroid carcinoma is a solid malignant tumor that has had fast-growing incidence in recent years. Our research used thyroid gene expression profiling from TCGA (The Cancer Genome Atlas) database to identify differentially expressed ceRNAs. Using the 502 tissues and 58 normal database, we established carcinoma-specific competitive endogenous RNA (ceRNA) network found nine overall survival (OS)-associated genes ( PRDM1, TGFBR3, E2F1, FGF1, ADAM12, ALPL, RET, AL928654.2, AC128688.2 ). We...
Background The hospital supply chain has revealed increasing vulnerabilities and disruptions in the wake of COVID-19 pandemic, threatening healthcare services patient safety. resilience chains emerged as a paramount concern within system. However, there is lack systematic research to develop an instrument tailored industry that both valid reliable for measuring resilience. Therefore, this study aims construct validate comprehensive scale assessing resilience, based on dynamic capability...
Abstract Background Nucleolar spindle-associated protein 1 (NUSAP1) is reported to be a useful diagnostic and prognostic marker for variety of cancers, but relevant studies are lacking in papillary thyroid carcinoma (PTC). Methods The relationship between NUSAP1 expression the overall survival (OS) pan-cancer was examined by GEPIA KMplot. We explored clinical PTC data based on THCA dataset TCGA GEO NCBI; GO, KEGG analysis, ceRNA networks were performed co-expressed genes through LinkedOmics...
The aim of the present study was to explore risk factors diabetes peripheral neuropathy (DPN) in type 2 mellitus, and propose corresponding nursing intervention measures provide basis for early diagnosis, treatment prevention DPN. A retrospective analysis performed on 130 patients with mellitus (T2DM) communities surrounding our hospital from January 2017 June 2018. They were divided into a DPN group (62 cases) non‑DPN (control group, 68 cases). First,...
Abstract Background Plant miRNAs are involved in the response to biotic and abiotic stresses by altering their expression levels, they play an important role regulation of plant resistance stress. However, molecular mechanism that regulates levels plants with stress still needs be explored. Previously, we found miR482 family was changed tomato infected Botrytis cinerea . In this study, investigated uncovered underlying B. infection tomato. Results First, RT-qPCR employed detect patterns...
Excessive lung inflammation caused by endotoxins, including lipopolysaccharide (LPS), mediates the detrimental effects of acute injury (ALI), as evidenced severe alveolar epithelial cell injury. CD40, a member tumor necrosis factor receptor superfamily, serves central activator in triggering and transducing series inflammatory events during pathological processes ALI. Ginkgolide C (GC) is an efficient specific inhibitor CD40. Therefore, present study aimed to investigate whether GC...
Background: Globally, gastric cancer (GC) is still a major leading cause of cancer-associated deaths. Downregulated desmocollin2 (DSC2) considered to be closely related tumor progression. However, the underlying mechanisms DSC2 in GC progression require further exploration. Method: We initially constructed different cells based on contents, established mouse xenografts, and subsequently performed clonal formation, MTT, Caspase-3 activity, sperm DNA fragmentation assays detect functions...
Abstract Background Some gastrointestinal disorders may be associated with Helicobacter pylori infection, which not only affect maternal health, but also lead to adverse pregnancy outcomes. We aim explore the association between H. and in pregnant women. Materials Methods In total, 503 patients were retrospectively analyzed divided into pylori‐ uninfected group, infected or eradicated group. influence of on diseases during among groups, as well severity, symptoms, laboratory tests related...
Chemokine (C-C motif) ligand 18 (CCL18) is a chemokine that plays key role in immune and inflammatory responses. In recent years, CCL18 participates the development progression of various cancers, but its expression thyroid cancer (TC) remain unclear.RT-qPCR assay Western blot were used to explore level TC tissues cells. Cell proliferation was measured by MTT assay. Transwell adopted detect cell migration Dual luciferase reporter performed assess relationship between miR-149-5p.There an...
Background. Previous studies have shown that Ampelopsin has an inhibitory effect on human tumors. However, the of renal cell carcinoma (RCC) is rarely reported. Therefore, this study aims to explain role in RCC. Methods. Different concentrations (0, 10, 25, 50, and 100 μM) were used treat 786-O cells. Cell viability was detected by MTT assay, colony formation flow cytometry assay. Transwell assay Wound healing detect migration invasion. Western blot analysis applied protein expression....