A5085005422- Genomics and Rare Diseases
- Genomic variations and chromosomal abnormalities
- Genomics and Phylogenetic Studies
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Full-Duplex Wireless Communications
- Wireless Networks and Protocols
- Hair Growth and Disorders
- Cancer-related molecular mechanisms research
- Molecular Biology Techniques and Applications
- Cooperative Communication and Network Coding
- Chromosomal and Genetic Variations
- RNA and protein synthesis mechanisms
- Immune Cell Function and Interaction
- Genetic diversity and population structure
- Cancer Genomics and Diagnostics
University of Chinese Academy of Sciences
2020-2024
Shanghai Institute of Nutrition and Health
2022-2024
Human genomics is witnessing an ongoing paradigm shift from a single reference sequence to pangenome form, but populations of Asian ancestry are underrepresented. Here we present data the first phase Chinese Pangenome Consortium, including collection 116 high-quality and haplotype-phased de novo assemblies based on 58 core samples representing 36 minority ethnic groups. With average 30.65× high-fidelity long-read coverage, contiguity N50 more than 35.63 megabases total size 3.01 gigabases,...
Abstract Background Hmong–Mien (HM) speakers are linguistically related and live primarily in China, but little is known about their ancestral origins or the evolutionary mechanism shaping genomic diversity. In particular, lack of whole-genome sequencing data on Yao population has prevented a full investigation history HM speakers. As such, debatable. Results Here, we made deep effort 80 genomes, our analysis together with 28 East Asian populations 968 ancient genomes suggested that there...
The human leukocyte antigen (HLA) system, or the version of major histocompatibility complex (MHC), is known for its extreme polymorphic nature and high heterogeneity. Taking advantage whole-genome whole-exome sequencing data, we developed PGG.MHC to provide a platform explore diversity MHC in Asia as well global populations. currently archives high-resolution HLA alleles 53 254 samples representing 190 populations spanning 66 countries. provides: (i) high-quality allele frequencies eight...
Abstract Human genomics is witnessing an ongoing paradigm shift from a single reference sequence to pangenome form but populations of Asian ancestry are underrepresented. Here, we present the first effort (Phase I) Chinese Pangenome Consortium (CPC) with collection 116 high-quality and haplotype-phased de novo assemblies based on 58 core samples representing 36 minority ethnic groups. With > 30.65× High-Fidelity long-reads coverage, average contiguity N50 35.63 Mb, total size 3.01 Gb, CPC...
Batch forwarding using intra-flow random linear network coding (RLNC) has been used to improve the performance of a wireless constituent lossy links. However, existing batch-based mechanisms in this aspect can lead lot bandwidth waste and thus reduced transmission efficiency. In paper, we design Sliding WIndow based Multiple batch mechanism (SWIM) RLNC. SWIM, multiple batches are allowed be sent out simultaneously way that process is managed by sliding window. adaptive rate assignment assign...