A5061419521- Gastric Cancer Management and Outcomes
- Glycosylation and Glycoproteins Research
- Monoclonal and Polyclonal Antibodies Research
- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Rheumatoid Arthritis Research and Therapies
- Galectins and Cancer Biology
- Systemic Lupus Erythematosus Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Vasculitis and related conditions
- Vascular Tumors and Angiosarcomas
- Advanced X-ray and CT Imaging
- Liver Disease Diagnosis and Treatment
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immunotherapy and Immune Responses
- Dermatologic Treatments and Research
- Otitis Media and Relapsing Polychondritis
- Pharmacological Effects of Natural Compounds
- Ferroptosis and cancer prognosis
- Systemic Sclerosis and Related Diseases
- Medical Imaging Techniques and Applications
- Bone Metabolism and Diseases
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Screening and Detection
- Magnolia and Illicium research
Zhengzhou University
2011-2025
Zunyi Medical University
2025
Peking University People's Hospital
2013-2024
Peking University
2005-2024
Tang Hospital
2017-2022
University Gastroenterology
2020
Ningbo No. 2 Hospital
2017
Peking University First Hospital
2005-2007
Gastrointestinal tumors represent a significant component of the cancer burden in Asia. This study aims to evaluate gastrointestinal Asia from 1990 2021 using data Global Burden Disease Study (GBD 2021).
Background: Primary cardiac tumors are rare. Most primary benign, with approximately 10.83% being malignant. We present a rare case of Cardiac Angiosarcoma (PCA) multiple metastases diagnosed using multimodality imaging, to enhance the understanding PCA among clinicians and radiologists. Case Description: A 29-year-old woman presented our hospital 2-day history chest tightness, pain, palpitations, dyspnea after physical activity. Ultrasonography Computed Tomography (CT) heart revealed mass...
Abstract Background This study aims to screen, validate novel biomarkers and develop a user-friendly online tool for the detection of colorectal cancer (CRC). Methods Multi-omics approach, comprising proteomic analysis single-cell transcriptomic analysis, was utilized discover candidate tumor-associated antigens (TAAs). The presence autoantibodies (TAAbs) in serum subsequently assessed using enzyme-linked immunosorbent assays (ELISA) 300 CRC patients healthy controls. Ten machine learning...
A number of studies have shown that cyclooxygenase-2 (COX-2) gene polymorphisms were associated with gastric cancer. However, the results from different research groups not been consistent. The present study aimed to investigate association between promoter region (-1195G>A, -765G>C) and cancer patients various degrees relationship in Chinese Han population. COX-2-1195G>A COX-2-765G>C 296 319 control family members genotyped using polymerase chain reaction-restriction fragment length...
Summary Objective Propylthiouracil (PTU) has been known to induce myeloperoxidase‐antineutrophil cytoplasmic antibody (MPO‐ANCA) positive vasculitis. Our previous study indicated that the increase of avidity MPO‐ANCA might be associated with occurrence clinical vasculitis in patients PTU‐induced ANCA. The current aimed follow‐up and titre anti‐MPO antibodies sequential sera from ANCA‐associated systemic (AASV). Methods Six were enrolled study. Serial both active phase remission collected....
Background Autoantibodies targeting tumor-associated antigens (TAAbs) have emerged as promising biomarkers for early cancer detection. This research aimed to assess the diagnostic capacity of anti-BIRC5 autoantibody in detecting AFP-negative hepatocellular carcinoma (ANHCC). Methods was carried out three stages (discovery phase, validation and evaluation phase) included a total 744 participants. Firstly, discovered using protein microarray, exhibiting higher positive rate ANHCC samples...
Objectives The health-related quality of life (HRQoL) and utilities patients with chronic hepatitis B (CHB) virus infection, including compensated cirrhosis (CC), decompensated (DC) different stages hepatocellular carcinoma (HCC), have not been well described in China. This study aimed to evaluate HRQoL provide parameters for the economic evaluation CHB-related diseases. Methods We conducted a multicentre cross-sectional measure CHB, CC, DC HCC using Chinese short form (SF) 36 health survey...
The postoperative recurrence risk of gastrointestinal stromal tumour (GIST) should be estimated when considering adjuvant systemic therapy. Previous studies in the literature have suggested that small intestinal GISTs are more aggressive than gastric GISTs. We assessed prognostic role primary site patients with operable GIST to compare outcomes and over a decade treatment. Surveillance, Epidemiology, End Results (SEER) database was queried for cases between 2004 2014 using GIST-specific...
The serological biomarkers as noninvasive tests are the most promising way for diagnosing gastric cancer (GC). Serological proteome analysis (SERPA) has been used to identify tumor-associated antigens (TAAs) and corresponding autoantibodies in many studies. To explore relationship between development serum autoantibody anti-GRP78 response found by method of SERPA with GC cell line AGS, we included two cohorts (133 133 normal individuals test group; 300 validation group) patients newly...
This study was aimed to explore the differential diagnosis value of preinvasive lesions/minimally invasive adenocarcinoma and manifesting as small pulmonary nodules under dual source computed tomography (DSCT) imaging. The patients with nodular manifestations in situ (AIS)/microinfiltrating (MIA) were selected group X, including 14 cases. A total 31 cases infiltrating Y. enhanced dual-energy image obtained by DSCT scan transferred software obtain energy iodine distribution map. SPSS 18.0...
Aim: Peroral endoscopic myotomy (POEM) is recommended for the treatment of achalasia and esophageal junction outflow obstruction (EGJOO); however, absent contractility, a subtype peristalsis disorders classified by Chicago Classification motility v3.0, has no effective treatment. The purpose this study was to assess efficacy POEM in part patients presents with dysphagia. Methods: We conducted single-center retrospective at tertiary referral center. included 30 who mainly complain dysphagia,...
Objective To evaluate the current status usage, treatment adherence and adverse effects of etaner-cept in real clinical practice Chinese rheumatoid arthritis (RA) ankylosing spondylitis (AS) subjects. Methods This was a 52-week open-label, multicenter, observational study, conducted RA AS subjects receiving etanercept. The use dosage recommendations for etanercept were made according to physician's decision. rate effect evaluated. Treatment calculated by actual dosing/expected dosing...
Objective To investigate the effects of omeprazole combined with flupentixol melitracen on levels serum gastrin (GAS), motilin (MOT) and quality life in patients reflux esophagitis (RE). Methods Seventy-two RE were randomly divided into study group control group, 36 cases each group. Patients treated only + melitracen, two groups for 2 months. The clinical efficacy incidence adverse reactions between after treatment compared, life, hamilton depression scale (HAMD), anxiety score...
Abstract Background This study aims to evaluate the clinicopathological characteristics of metastatic hepatocellular carcinoma (HCC) patients and develop nomograms predict their long-term overall survival (OS) cancer-specific (CSS). Methods Information on HCC from 2010 2015 was retrieved Surveillance, Epidemiology End Results (SEER) program National Cancer Institute. The were divided into a (LTS) group short-term (STS) with 1 year selected as cut-off value. Then, we compared demographic...