A5076959099- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Neuroscience of respiration and sleep
- Infant Development and Preterm Care
- Non-Invasive Vital Sign Monitoring
- Sepsis Diagnosis and Treatment
- Congenital Heart Disease Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Neonatal and Maternal Infections
- EEG and Brain-Computer Interfaces
- Fetal and Pediatric Neurological Disorders
- Congenital Diaphragmatic Hernia Studies
- Anesthesia and Neurotoxicity Research
- Cardiac Arrest and Resuscitation
- Prenatal Substance Exposure Effects
- Cardiovascular Conditions and Treatments
- Optical Imaging and Spectroscopy Techniques
- Emergency and Acute Care Studies
- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Phonocardiography and Auscultation Techniques
- Neonatal Health and Biochemistry
- Retinopathy of Prematurity Studies
- Epilepsy research and treatment
- Birth, Development, and Health
Washington University in St. Louis
2016-2025
Mallinckrodt (United States)
2015-2023
Universitair Ziekenhuis Leuven
2022
KU Leuven
2022
Centre Hospitalier Universitaire Sainte-Justine
2022
Université de Montréal
2022
St. Louis Children's Hospital
2015-2022
University of Washington
2022
Museum of Heilongjiang Province
2021
National Center for Advancing Translational Sciences
2019
The use of cerebral oximetry monitoring in the care extremely preterm infants is increasing. However, evidence that its improves clinical outcomes lacking. Download a PDF Research Summary. In this randomized, phase 3 trial conducted at 70 sites 17 countries, we assigned (gestational age, <28 weeks), within 6 hours after birth, to receive treatment guided by for first 72 birth or usual care. primary outcome was composite death severe brain injury on ultrasonography 36 weeks' postmenstrual...
Importance Socioeconomic status affects pregnancy and neurodevelopment, but its association with hospital outcomes among premature infants is unknown. The Area Deprivation Index (ADI) a validated measure of neighborhood disadvantage that uses US Census Bureau data on income, educational level, employment, housing quality. Objective To determine whether ADI associated neonatal intensive care unit (NICU) mortality morbidity in extremely infants. Design, Setting, Participants This retrospective...
Although evidence suggests that methylxanthines may lower the seizure threshold, effect of high-dose caffeine on burden in preterm infants is not known. This study reports a secondary
Objective To review developmental outcomes of neonates with mild hypoxic-ischemic encephalopathy (HIE) treated therapeutic hypothermia (TH). Study Design Neonates ≥35 weeks' gestation HIE/TH (TH group, n = 30) were matched healthy term-born infants (control and reviewed for the presence severity magnetic resonance imaging (MRI)-detected neurological injury. Neurodevelopmental assessed using Bayley Scales Infant Development (BSID). Results MRI injury was present in 13/30 (43.3%) (11 mild, 1...
In premature infants, clinical changes frequently occur due to sepsis or non-infectious conditions, and distinguishing between these is challenging. Baseline risk factors, vital signs, signs guide decisions culture start antibiotics. We sought compare heart rate (HR) oxygenation (SpO2) patterns as well baseline variables prompting work-ups ultimately determined be late-onset (LOS) ruled out (SRO). At three NICUs, we reviewed records of very low birth weight (VLBW) infants around their first...
Abstract Mortality remains an exceptional burden of extremely preterm birth. Current clinical mortality prediction scores are calculated using a few static variable measurements, such as gestational age, birth weight, temperature, and blood pressure at admission. While these models do provide some insight, numerical time-series vital sign data also available for babies admitted to the NICU may greater insight into outcomes. Computational that predict risk in by integrating variables real...
Purpose: Neonatal encephalopathy (NE) is a commonly encountered, highly morbid condition with pressing need for accurate epilepsy prognostication. We evaluated the use of automated EEG prediction early life after NE treated therapeutic hypothermia (TH). Methods: conducted retrospective analysis neonates moderate-to-severe who underwent TH at single center. The first 24 hours data artifact removal and quantitative (qEEG) subsequent evaluation qEEG feature accuracy 1st 20th hour risk...