A5046718396- Skin and Cellular Biology Research
- Cancer and Skin Lesions
- melanin and skin pigmentation
- COVID-19 Clinical Research Studies
- Hair Growth and Disorders
- Dermatology and Skin Diseases
- Genetic and rare skin diseases.
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Autoimmune Bullous Skin Diseases
- Cell Adhesion Molecules Research
- Atherosclerosis and Cardiovascular Diseases
- Psoriasis: Treatment and Pathogenesis
- COVID-19 diagnosis using AI
- Nonmelanoma Skin Cancer Studies
- Dermatological and Skeletal Disorders
- Ubiquitin and proteasome pathways
- Hedgehog Signaling Pathway Studies
- RNA regulation and disease
- Connexins and lens biology
- Advanced Photocatalysis Techniques
- Acne and Rosacea Treatments and Effects
- SARS-CoV-2 detection and testing
- NF-κB Signaling Pathways
- Herpesvirus Infections and Treatments
Southern Medical University Shenzhen Hospital
2017-2025
Chongqing Medical University
2025
Guangdong Academy of Medical Sciences
2024
Guangdong Provincial People's Hospital
2024
Southern Medical University
2013-2024
Beijing Children’s Hospital
2023
Capital Medical University
2023
China Three Gorges University
2022-2023
Shenzhen Third People’s Hospital
2020-2022
Southern University of Science and Technology
2020-2022
This study aims to evaluate the correlation between viral clearance and blood biochemical index of 94 discharged patients with COVID-19 infection in Shenzhen Third People's Hospital, enrolled from Jan 5 Feb 13, 2020. The clinical laboratory findings were extracted electronic medical records patients. data analysed reviewed by a trained team physicians. Information on signs symptoms, treatment, virus clearance, parameters including interleukin 6 (IL-6) C-reactive protein collected. mRNA ratio...
We report the observation that 14.5% of COVID-19 patients had positive RT-PCR testing again after discharge. describe correlations between laboratory parameters and treatment duration (P = .002) time to virus recrudescence .008), suggesting need for additional measures confirm illness resolution in patients.
Abstract Background Thousands of Coronavirus Disease 2019 (COVID-19) patients have been discharged from hospitals Persistent follow-up studies are required to evaluate the prevalence post-COVID-19 fibrosis. Methods This study involves 462 laboratory-confirmed with COVID-19 who were admitted Shenzhen Third People’s Hospital January 11, 2020 April 26, 2020. A total 457 underwent thin-section chest CT scans during hospitalization or after discharge identify pulmonary lesion. 287 followed up 90...
Alopecia areata (AA) is hypothesized to be an organ-specific autoimmune disease with genetic predisposition and environmental trigger. There are few clinical data in Asians.To describe the epidemiological features of AA patients China determine possible model for AA.Data 1032 were obtained by questionnaire Institute Dermatology Anhui Medical University from 2001 2003. Complex segregation analysis heritability performed using Falconer's method, EPI INFO 6.0 SAGE-REGTL programs.In total,...
Abstract: To study the clinical and epidemiologic profile of childhood alopecia areata, we performed a survey in which total 226 patients less than 16 years old were enrolled. Statistical analysis heritability using EPI INFO 6.0, SPSS10.0, Falconer method. The median age onset was 10 years. majority (84.96%) presented with limited alopecia. male : female ratio 1.4:1. Boys appeared to have more severe involvement. earlier onset, greater severity disease. Sixty‐seven (29.65%) had previous...
PSORS1 (psoriasis susceptibility gene 1) is a major locus for psoriasis. Several fine-mapping studies have highlighted 300-kb candidate region of where multiple biologically plausible genes were suggested. The most recent study has indicated HLA-Cw6 as the primary risk allele within in Caucasian population. In this study, family-based association analysis was performed by analyzing 10 polymorphic microsatellite markers from well HLA-B, HLA-C and CDSN loci 163 Chinese families Five marker...
Our previous genome-wide linkage analysis identified a susceptibility locus for generalized vitiligo on 22q12. To search genes within the locus, we investigated biological candidate gene, X-box binding protein 1(XBP1). First, sequenced all exons, exon-intron boundaries as well some 5' and 3' flanking sequences of XBP1 in 319 cases 294 controls Chinese Hans. Of 8 common variants identified, significant association was observed at rs2269577 (p_(trend) = 0.007, OR 1.36, 95% CI 1.09-1.71),...
SHARPIN, as a tumor-associated gene, is involved in the metastatic process of many kinds tumors. Herein, we studied function Shank-associated RH domain interacting protein (SHARPIN) melanoma metastasis and relevant molecular mechanisms. We found that SHARPIN expression was increased tissues activated proliferation, migration, invasion vitro vivo, resulting poor prognosis disease. Functional analysis demonstrated promoted migration by regulating Ras-associated protein-1(Rap1) its downstream...
Introduction Colistin has emerged as the last resort for treating multidrug-resistant Enterobacter cloacae complex (ECC) infections. The primary purposes of this study were to demonstrate presence colistin heteroresistance in ECC and further investigate their clinical characteristics, molecular epidemiology mechanisms. Methods Population analysis profiles (PAP) performed confirm phenotype. Average nucleotide identity (ANI) was determined classify species. Phylogenetic based on core genome...
Due to the complexity of identifying Enterobacter cloacae complex (ECC) at species level, little is known about distribution carbapenem-resistant ECC (CRECC). Plasmid-mediated mcr family genes are significant contributors polymyxin resistance. The emergence mcr-9 gene has further complicated landscape resistance in CRECC. Our study aimed ascertain prevalence CRECC and gene, elucidate mechanisms underlying high-level B (PB). In this study, we collected 212 non-replicating strains, 38 strains...
Three methods are currently available to reconstitute hair follicles in mice. Direct comparisons have yet be made determine which method is most efficient. In this study, mouse epithelial cells (MECs) and dermal (MDCs) were grafted onto the dorsal skin of nude mice using chamber, flap or patch assays. Comparisons based on gross, scanning electron microscopic histological observations. MDCs alone induced follicle reconstitution with production hairs yielding false-positive results caused by...