- Fatty Acid Research and Health
- Eicosanoids and Hypertension Pharmacology
- Cholesterol and Lipid Metabolism
- Peroxisome Proliferator-Activated Receptors
- Phosphodiesterase function and regulation
- Impact of Technology on Adolescents
- Antioxidant Activity and Oxidative Stress
- Educational Methods and Impacts
- Adipose Tissue and Metabolism
- Adenosine and Purinergic Signaling
- Sphingolipid Metabolism and Signaling
- Child Development and Digital Technology
- Lipid metabolism and biosynthesis
- Drug Transport and Resistance Mechanisms
- Healthcare professionals’ stress and burnout
- Nuts composition and effects
- Alcohol Consumption and Health Effects
- Pharmacology and Obesity Treatment
- Cardiac Imaging and Diagnostics
- Diabetes Treatment and Management
- Pregnancy and Medication Impact
- Aquaculture Nutrition and Growth
- Protein Kinase Regulation and GTPase Signaling
- Ginger and Zingiberaceae research
- Complement system in diseases
Université Ibn-Tofail
2023-2024
University of Hassan II Casablanca
2012-2018
Université Hassan II Mohammedia
2006-2016
Inserm
1990-1999
Institut National des Sciences Appliquées de Lyon
1991-1999
Laboratoire de Chimie
1990-1994
Abstract Background Dietary changes are a major factor in determining cardiovascular risk. n -3 polyunsaturated fatty acids modulate the risk factors for metabolic syndrome via multiple mechanisms, including regulation of lipid metabolism. We therefore investigated effect Odontella aurita , microalga rich EPA, which is already used as food supplement, on high-fat diet induced rats. Methods Male Wistar rats were divided into 4 groups and fed with standard (control); supplemented 3%...
Abstract Dietary supplementation with marine omega‐3 polyunsaturated fatty acids (n‐3 PUFA) can have beneficial effects on a number of risk factors for cardiovascular disease (CVD). We compared the two n‐3 PUFA rich food supplements (freeze‐dried Odontella aurita and fish oil) CVD. Male rats were randomly divided into four groups six animals each fed following diets: control group (C) received standard diet containing 7 % lipids; second (HF high fat) was high‐fat 40 third (HFFO fat+fish...
Marine microalgae are photosynthetic microorganisms producing numerous bioactive molecules of interest for health and disease care such as lipids rich in omega-3 fatty acids -as eicosapentaenoic acid (EPA, 20:5 n-3) docosahexaenoic (DHA, 22:6 n-3)- carotenoids (e.g., β-carotene, fucoxanthin, astaxanthin). It has already been shown that these molecules, individually used, benefic the prevention diseases those associated with cardiovascular risks, but also some carcinomas. When combined,...
Abstract Background It is now established that patients with hyperlipidemia have a high risk of atherosclerosis and thrombotic complications, which are two important events responsible for the onset progression cardiovascular disease. In context managing dyslipidemia by means dietary advice based on consumption argan oil, we wanted to investigate effect virgin oil plasma lipids, first time, platelet hyperactivation oxidative status associated dyslipidemia. This study concerns recruited in...
The study focuses on the intricate relationship between excessive smartphone use, insomnia, and academic performance among middle school adolescents in Kenitra, Morocco. It also seeks to understand how gender type influence these variables what implications this may have for well-being of adolescents. Data were collected through specific questionnaires assessing usage (SAS), levels insomnia (measured by ISI score), (S2 grades) from various schools, both public private. These data then...
The beneficial effect of polyunsaturated omega-3 fatty acid (w-3 FA) consumption regarding cardiovascular diseases, insulin resistance and inflammation has been widely reported. Fish oil is considered as the main source commercialized w-3 FAs, other alternative sources have reported such linseed or microalgae. However, despite numerous reports, underlying mechanisms action FAs on are still not clearly established, especially those from Here, we report that Odontella aurita , a microalga rich...
Abstract Cyclic nucleotide phosphodiesterase activity of human peripheral blood mononuclear cells was significantly increased following a short (30 min) incubation with the mitogenic lectin Concanavalin A. Con A stimulated to same extent whatever subcellular compartment (homogenate, cytosol or pellet). Further separation A‐activated into lymphocyte‐enriched and monocyte‐enriched populations showed that A‐induced increase exclusively affected population. In lymphocytes, cyclic GMP more...
Teaching has been identified as one of a highly stressful jobs. As known, this job is linked to development neuropsychiatric. However, there little background about the assessment these problems among Moroccan teachers. This study aims measure prevalence stress, anxiety and depression 150 newly recruited contractual primary teachers in KHEMISSET city using three international scales. The perceived stress scale (PSS) for hospital (HADS) Mini International Neuropsychiatric Interview (MINI)...
1. Since ageing has been associated with a decrease in both immune responses and antioxidant defences, this study was undertaken to compare the glutathione peroxidase activity peripheral blood mononuclear cells of healthy elderly young donors. The mean value significantly lower aged group (-36%) than that observed control (n = 10). 2. This defect accompanied by marked increase (+106%) oxygenated metabolism endogenous arachidonic acid lipoxygenases as judged radiolabel hydroxyeicosatetraenoic...
The influence of 12( S )‐hydroxyicosatetraenoic acid (12‐HETE), that we have previously shown to decrease the proliferative response human lymphocytes mitogens, on diacylglycerol and phosphatidic (PtdOH) formation was investigated in stimulated peripheral blood mononuclear cells (PBMC). When PBMC were first enriched with 12‐HETE, then by mitogenic lectin concanavalin A (Con A), production PtdOH normally associated Con stimulation markedly increased as compared non‐enriched cells....
Abstract 12‐hydroxy‐eicosatetraenoic acid (12‐HETE), the lipoxygenase metabolite of arachidonic produced by activated platelets, has been shown to accumulate in peripheral blood mononuclear cells (PBMC) elderly people. 12‐HETE being antimitogenic for lymphocytes, its accumulation might be involved well‐known decline immune function which accompanies aging. Because HETEs have rapidly metabolized and/or incorporated into cellular lipids a variety cell types, we investigated uptake, metabolism,...
Abstract Background Adolescents face various addiction issues, including excessive smartphone use, which significantly impacts their mental health, leading to anxiety and depression. This study aimed analyze the impact of use on health middle school adolescents in city Kenitra, Morocco, focusing particularly prevalence depression identify factors influencing these behaviors. The present cross-sectional included a sample 341 from Kenitra city, Morocco. Participants completed comprehensive...
all around the world, type 2 diabetes is considered a metabolic disease that generates complications can be very serious, even fatal, over time, especially if not properly managed. Clinical and biological parameters in blood glucose levels will assessed this study (N=300 patients). We assess prevalence of caused by including diabetic retinopathy, nephropathy, neuropathy, cardiovascular diseases. Type an incurred disease, but it Self-therapeutic education therefore imperative highly...
1. Both adenosine 3′:5′-cyclic monophosphate and guanosine phosphodiesterase activities of peripheral blood mononuclear cells were markedly decreased in elderly women as compared with young control women. 2. In contrast, the ability these to bind 5′-[β, γ-imido]triphosphate, a non-hydrolysable analogue 5′-triphosphate, was same both groups. 3. These findings are discussed context decline immune function which occurs increasing age.
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
L'effet de la granulométrie du son blé et sa concentration sur les caractéristiques organoleptiques pain acceptabilité par le consommateur ont été évalués.Le tendre a ajouté, à trois concentrations (21%, 14% 7 %) granulométries (1mm, 1,4 mm 1,8 mm), une farine type T65.Ainsi, neuf pains préparés, en plus d'un témoin (à 0% son).Les préparés soumis quelques analyses (volume spécifique, brunissement croûte mie pain, paramètres texturaux).Ces évalués visuellement gustativement population 106...