A5056584987- Ferroptosis and cancer prognosis
- Speech and Audio Processing
- Enhanced Recovery After Surgery
- Speech Recognition and Synthesis
- Textile materials and evaluations
- Cancer-related molecular mechanisms research
- Genetic factors in colorectal cancer
- Catalytic Processes in Materials Science
- Helicobacter pylori-related gastroenterology studies
- Hedgehog Signaling Pathway Studies
- Agriculture Sustainability and Environmental Impact
- Music Therapy and Health
- Extracellular vesicles in disease
- TiO2 Photocatalysis and Solar Cells
- Innovative Energy Harvesting Technologies
- Anodic Oxide Films and Nanostructures
- Advanced Adaptive Filtering Techniques
- Hereditary Neurological Disorders
- Meat and Animal Product Quality
- Neurological diseases and metabolism
- Acupuncture Treatment Research Studies
- Endoplasmic Reticulum Stress and Disease
- Animal Nutrition and Physiology
- Advanced Photocatalysis Techniques
- Peptidase Inhibition and Analysis
Fujian Medical University
2025
China Three Gorges University
2024-2025
First Affiliated Hospital of Fujian Medical University
2025
First Affiliated Hospital of Anhui Medical University
2025
Anhui Medical University
2025
Beijing National Laboratory for Molecular Sciences
2024
Peking University
2024
Hunan University of Traditional Chinese Medicine
2023-2024
Northwestern Polytechnical University
2023
Shenzhen University
2023
The purpose was to provide an overview of genotype and phenotype distribution in a cohort patients with Charcot-Marie-Tooth disease (CMT) related disorders from central south China.In all, 435 were enrolled detailed clinical data collected. Multiplex ligation-dependent probe amplification for PMP22 duplication/deletion CMT multi-gene panel sequencing performed. Whole exome further applied the remaining who failed achieve molecular diagnosis.Among patients, 216 had CMT1, 14 hereditary...
Liver cancer is a common second primary in gastric patients, but whether diagnosis contributes to the development of liver remains contentious. This study aims utilize Mendelian randomization (MR) analysis investigate potential causal relationship between and from genetic perspective. We extracted single nucleotide polymorphism for East Asian population Genome-Wide Association Studies database as instrumental variables employed univariate multivariate MR evaluate cancer. The robustness...
This paper presents an improved egg carrier for supporting common types of eggs during slit inspection platform opeations. The conveys the forwards to position. consists three basic modules and has advantages adaptability, adjustability, low maintenance manufacturing costs, stable efficient operation. First, functions are analysed, preliminary design concepts solutions proposed via TRIZ theory. Second, structure is designed, material properties key parameters such as deformation simulated by...
Lung cancer is frequently observed as a second primary malignancy following gastric cancer, yet the genetic causality between them remains uncertain. This study aims to evaluate causal relationship and lung cancers using Mendelian randomization (MR) analysis. Single nucleotide polymorphisms associated with were selected from Genome-Wide Association Study in East Asian European populations instrumental variables. The effects evaluated univariable multivariable MR analysis, inverse variance...
Rationale: The association between Barrier to Autointegration Factor 1 (BANF1) and various human diseases has been recently reported. However, its role mechanism in colorectal cancer (CRC) initiation progression remain unexplored. Methods: This study examined BANF1 expression CRC tissues cells using bioinformatics databases, PCR, Western Blot (WB), immunohistochemistry (IHC). of the was evaluated through both vitro vivo experiments. RNA sequencing employed explore potential mechanisms, which...
Abstract Head and neck squamous cell carcinoma (HNSCC) is a heterogeneity pathological malignant cancer with leading causes of morbidity mortality. EGFR inhibitors, immune checkpoint inhibitors have become novel treatments. However, the mechanism still remained uncertain. Several studies confirmed that circadian rhythms induce multiple malignancies developing. We utilized multi-omics analysis to demonstrate crosstalk between clock genes tumor microenvironment in HNSCC. Firstly, we performed...
Photothermal therapy allows spatiotemporal control of the treatment effect only at site disease and provides promising opportunities for imaging-guided precision therapy. However, development photothermal transduction agents (PTAs) tumor-specific accumulation imaging, avoiding toxicity to surrounding healthy tissue, is still challenging. Herein, a cyclooxygenase-2-specific small-organic-molecule-based PTA (Cy7-TCF-IMC) developed, which can self-assemble into nanosaucers having unique...
In this paper, a real-time wireless respiratory monitoring system using dual pair of detectors-based thermal flow (D <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> TF) sensor with wide linear range is reported. The D TF structure and packaging are optimized to achieve -70 SLM ~ 70 (-4 m/s 4 m/s) sensitivity 9.18 mV/SLM. Moreover, the developed shows response time less than 23 ms data sample rate 2 kHz, which can capture sharp signal...
Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous cancer with high morbidity mortality. Triggering the programmed death (PCD) to enhance anti-tumor therapies being applied in multiple cancers. However, limited understanding of genetic heterogeneity HNSCC severely hampers clinical efficacy. We systematically analyzed 14 types PCD from The Cancer Genome Atlas (TCGA). utilized ssGSEA calculate scores classify patients into two clusters. Subsequently, we displayed genomic...
Metal-oxide interfaces with poor coherency have specific properties comparing to bulk materials and offer broad applications in heterogeneous catalysis, battery, electronics. However, current understanding of the three-dimensional (3D) atomic metal-oxide remains limited because their inherent structural complexity limitations conventional two-dimensional imaging techniques. Here, we determine 3D structure zirconium-zirconia nanoparticles using atomic-resolution electron tomography. We...
Muscle-invasive bladder cancer (MIBC) develops lymph node (LN) metastasis or distant metastasis, leading to recurrence and poor prognosis. The five-year survival rate of MIBC with LN is only 8.1%; therefore, there an urgent need identify reliable biomarkers for prognosis treatment regimen patients (BLCA).SEER database was used select important clinical characteristics MIBC. Then, weighted gene co-expression network analysis (WGCNA) employed differentially expressed genes (DEGs) recognize...
Amorphous materials have broad applications ranging from daily life to extreme conditions due their unique properties in elasticity, strength and resistivity. However, experimentally determining the three-dimensional (3D) atomic structure of amorphous has been a long-standing problem. Atomic resolution electron tomography (AET) proved an increasingly powerful tool for scale structural characterization without any crystalline assumptions. In this review, we summarize state-of-art methods...
The L3DAS23 of ICASSP Signal Processing Grand Challenge encourages research on 3D audio signal processing, such as speech enhancement (SE) and sound localization detection (SELD). In this paper, we propose a two-stage system based DPRNN UNet for the SE task Conformer-based SELD task. proposed systems are evaluated blind test sets. Results show that methods achieve state-of-the-art performance SELD.
Abstract The synthesis of triacylglycerol (TAG) is essential for the storage excess fatty acids, which can subsequently be used energy or cell growth. A series enzymes act in endoplasmic reticulum (ER) to synthesize TAG, prior its transfer lipid droplets (LDs), are conserved organelles fat storage. Here, we report that deficiency TMEM-120/TMEM120A, a protein with 6-transmembrane helices, retards TAG and LD expansion C. elegans . missense mutation near predicted coenzyme binding site TMEM-120...
<title>Abstract</title> Metal-oxide interfaces with poor coherency have unique properties comparing to the bulk materials and offer broad applications in fields of heterogeneous catalysis, battery, electronics. However, current understanding three-dimensional (3D) atomic metal-oxide remains limited because their inherent structural complexity limitations conventional two-dimensional imaging techniques. Here, we determine 3D structure zirconium-zirconia nanoparticles using atomic-resolution...
<title>Abstract</title> This paper presents an improved egg carrier for supporting common types of eggs currently available on the market during operation slit inspection platform. It can convey them forward to corresponding position. The consists three basic modules. has advantages adaptability different eggs, adjustability, low maintenance and manufacturing costs, stable efficient operation. Firstly, functions be realized by are analyzed, preliminary design ideas solutions proposed through...
3D speech enhancement can effectively improve the auditory experience and plays a crucial role in augmented reality technology. However, traditional convolutional-based methods have limitations extracting dynamic voice information. In this paper, we incorporate dual-path recurrent neural network block into U-Net to iteratively extract audio information both time frequency domains. And an attention mechanism is proposed fuse original signal, reference generated masks. Moreover, introduce loss...
Metal-oxide interfaces with poor coherency have unique properties comparing to the bulk materials and offer broad applications in fields of heterogeneous catalysis, battery, electronics. However, current understanding three-dimensional (3D) atomic metal-oxide remains limited because their inherent structural complexity limitations conventional two-dimensional imaging techniques. Here, we determine 3D structure zirconium-zirconia nanoparticles using atomic-resolution electron tomography. We...
Objective To explore the effect of multidisciplinary collaboration (MDT) nursing mode in perioperative colon cancer patients. Methods A total 40 patients admitted for surgery from October 2014 to April 2016 were selected as observation group, and a collaborative program was implemented. The received treated by routine January 2013 June control group.The operation tolerance, incidence postoperative complications, wound healing time, anastomotic fistula, hospitalization time score...