A5100416635- Reproductive System and Pregnancy
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Research
- Reconstructive Surgery and Microvascular Techniques
- Endometriosis Research and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Pregnancy and preeclampsia studies
- Diabetes Treatment and Management
- Traditional Chinese Medicine Studies
- Lipoproteins and Cardiovascular Health
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Orthopedic Surgery and Rehabilitation
- Cardiovascular Health and Disease Prevention
- Diet and metabolism studies
- Peripheral Artery Disease Management
- Cancer-related molecular mechanisms research
- Cardiovascular Disease and Adiposity
- Bone fractures and treatments
- Neonatal Respiratory Health Research
- Preterm Birth and Chorioamnionitis
- Atherosclerosis and Cardiovascular Diseases
- Lipid metabolism and disorders
Nanjing University
2025
Hengshui University
2024-2025
Nanjing Medical University
2016-2025
First Affiliated Hospital of Kunming Medical University
2020-2025
Kunming Medical University
2020-2025
Jiangsu Province Hospital
2023-2025
Harbin Medical University
2025
Nanjing General Hospital of Nanjing Military Command
2025
Fourth Affiliated Hospital of Harbin Medical University
2025
Chinese People's Liberation Army
2005-2025
Abstract In this article, four cases of free fibular osteocutaneous flap transfer are reported. The advantages the bone‐attached flap, its microsurgical anatomy, and design method isolation discussed in detail. Postoperative follow‐up showed success all with satisfactory functional recovery.
Background: Total knee arthroplasty has been increasingly used for young and active patients, prosthesis durability is important in these patients. The accuracy of implant placement one the major factors that determine long-term survival prosthesis. purpose this study was to compare prosthetic alignment between computer-assisted-navigation conventional total arthroplasties. Methods: From March 2007 June 2008, thirty-two patients with bilateral osteoarthritis underwent simultaneous same type...
Abstract Objectives Anti-melanoma differentiation-associated gene 5 positive (anti-MDA5+) DM has a close relationship with rapidly progressive interstitial lung disease (RPILD) and is associated high mortality. However, data regarding the time-dependent risk of RPILD deaths during progression are limited. We conducted this study to investigate whether death were or not in anti-MDA5+ DM. Methods assessed cohort 272 patients The clinical characteristics collected, COX regression was used...
Background The prognosis of anti-melanoma differentiation-associated gene 5 positive dermatomyositis (anti-MDA5 + DM) is poor and heterogeneous. Rapidly progressive interstitial lung disease (RP-ILD) these patients’ leading cause death. We sought to develop prediction models for RP-ILD risk in anti-MDA5 DM patients. Methods Patients with were enrolled two cohorts: 170 patients from the southern region Jiangsu province (discovery cohort) 85 northern (validation cohort). Cox proportional...
Abstract Background To assess the postprandial glucose‐lowering effect of human amylin analog pramlintide when given with insulin lispro in subjects type 2 diabetes, an emphasis on optimal dose timing relative to meals. Methods In this randomized, single‐blind, placebo‐controlled, five‐way crossover study, 19 diabetes using underwent five consecutive mixed‐meal tests. randomized order, received subcutaneous injections placebo at −15 min or 120‐µg −15, 0, +15, +30 standardized breakfast after...
Abstract STUDY QUESTION What is the mechanism of Tim-3+ regulatory T (Treg)-cell accumulation in decidua during early pregnancy and its disruption associated with recurrent loss (RPL)? SUMMARY ANSWER IL-27 Gal-9 secreted by trophoblasts activate Tim-3 signaling pathway CD4+ cells Treg so promote cells, abnormal expression impaired immunologic tolerance RPL patients. WHAT IS KNOWN ALREADY are better suppressors Teff cell proliferation, display higher proliferative activity than Tim-3− cells....
Although several lines of evidences suggest that the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism may be involved in pathophysiology schizophrenia, this association remains controversial. Here, we aim to investigate genetic between BDNF and schizophrenia explore whether could influence severity clinical symptoms schizophrenic patients a Chinese Han population.Genotyping was carried out 456 483 controls using fluorescence resonance energy transfer method. The patients'...
Purpose: This study aimed to investigate the role of sclerostin and dkk1 in bone metabolism type 2 diabetic patients. Methods: cross-sectional included 95 inpatients with diabetes mellitus. We divided patients into three groups (i.e., normal mineral density (BMD) group, osteopenia group osteoporosis group) based on their different BMD levels measured serum sclerostin, dkk1, 25-hydroxyvitamin D3 (25OHD3), turnover markers other biochemical data each group. Results: Significantly increased...
The inflammation score is currently regarded as a reliable composite index for comprehensive assessment of inflammatory status. However, the relationship between and cardiovascular disease (CVD) unclear. Thus, we aimed to explore association with CVD, well evaluate whether adhering healthy lifestyle could alleviate this association. We analyzed 6,164 participants aged ≥45 years who entered prospective cohort study China Longitudinal Study Health Retirement (CHARLS) 2011 2012 were followed up...
Abstract Background The screening and monitoring of gastric cancer is still a clinical challenge. Both N 6 -methyladenosine (m A) lncRNAs have been evidenced as critical regulators cancer, but their interaction potential in modulating tumor progression remain unclear. This study aimed to evaluate the function lncRNA LINC00968 biological processes, we discovered role KIAA1429, typical m A eraser, mediating function. Materials methods expression was assessed using PCR regulated by cell...
Background: Remplissage with Bankart repair (RMBR) is an arthroscopic procedure performed on <25% of lesions off-track Hill-Sachs (HSLs) that alters the insertion infraspinatus muscle into humeral head. However, effects RMBR surgery head displacement due to changes in biomechanics and kinematics have not been fully elucidated. Purpose: To evaluate how biomechanical kinematic post-RMBR glenohumeral joint influence using finite element analysis (FEA) method. Study Design: Controlled...
Objective To investigate the efficacy of weekly measurement β-human chorionic gonadotropin, estradiol, and progesterone levels for pregnancy assessment in patients with unexplained recurrent miscarriage. Methods We retrospectively included miscarriage whose serum were measured three or more times during early pregnancy. The divided into two groups according to outcomes. Δβ-human Δestradiol, Δprogesterone compared, corresponding cutoff values determined using receiver operating characteristic...
This meta-analysis aimed to estimate the prevalence and identify risk factors for conversion laparotomy during laparoscopic hysterectomy (LH) both benign malignant gynecologic conditions. A comprehensive search of PubMed, Embase, Cochrane Library was conducted studies published between January 2000 September 2024. Eligible reported in patients undergoing LH. Studies were assessed quality using Newcastle-Ottawa Scale (NOS), data extracted on patient demographics, surgical details, outcomes....
Background:Accurate risk stratification of non-ST segment elevation myocardial infarction (NSTEMI) patients is important due to great variability in mortality risk, but, date, no prediction model has been available. The aim this study was therefore establish a score predict in-hospital NSTEMI patients.
Abstract Background Few studies have explored the prognostic role of nontraditional lipid-related indicators in non-disabling ischemic cerebrovascular events (NICE). In this study, we aimed to investigate relationship between ratio non-high-density lipoprotein cholesterol high-density (non-HDL-C/HDL-C) and the1-year risk recurrent stroke patients with NICE. Methods Total (TC), HDL-C, patient information were collected at admission. Recurrent followed up 3, 6, 12 months after onset. Non-HDL-C...
Abstract Aim To assess metabolic effects and safety of Roux‐en‐Y gastric bypass (RYGB) versus conventional medication (CM) in obese Chinese patients with type 2 diabetes (T2DM). Methods This retrospective cohort study included 40 who underwent RYGB (mean age 44.1 years, body mass index [BMI] 33.3 kg/m ) 36 administered CM 49.4 BMI 32.1 ). The primary endpoint was achievement the triple (haemoglobin A1C [HbA1c] < 7.0%, low‐density lipoprotein cholesterol 2.6 mmol/L, systolic blood pressure...