A5101466575- Microplastics and Plastic Pollution
- Immune Cell Function and Interaction
- Recycling and Waste Management Techniques
- Air Quality and Health Impacts
- Immunotoxicology and immune responses
- Weed Control and Herbicide Applications
- Heme Oxygenase-1 and Carbon Monoxide
- Ferroptosis and cancer prognosis
- Asthma and respiratory diseases
- biodegradable polymer synthesis and properties
- Autophagy in Disease and Therapy
- IL-33, ST2, and ILC Pathways
- Pesticide and Herbicide Environmental Studies
- Indoor Air Quality and Microbial Exposure
- Graphene and Nanomaterials Applications
- Cancer Immunotherapy and Biomarkers
- Immune cells in cancer
- Epigenetics and DNA Methylation
- Glutathione Transferases and Polymorphisms
- Sirtuins and Resveratrol in Medicine
- Lipid metabolism and biosynthesis
- Supercapacitor Materials and Fabrication
- Speech and dialogue systems
- Pesticide Exposure and Toxicity
- Nanoparticles: synthesis and applications
Tianjin University of Traditional Chinese Medicine
2025
Guangzhou University
2025
NGM Biopharmaceuticals (United States)
2022-2025
Southeast University
1996-2024
Jinan University
2024
Central China Normal University
2019-2022
Army Medical University
2020
PM2.5 and formaldehyde (FA) are major outdoor indoor air pollutants in China, respectively, both known to be harmful human health carcinogenic. Of all the chronic effects, leukaemia is one of most serious risks associated with these two pollutants. To explore influence underlying mechanisms exposure on hematopoietic toxicity, we systematically studied toxicity induced organs: bone marrow (BM); spleen; myeloid progenitor cells (MPCs). Male Balb/c mice were exposed to: (20, 160 μg/kg·d) at a...
Efficient written word recognition is crucial for effective reading and comprehension. However, whether deaf people recognize words through the same psychological mechanisms as those of hearing individuals remains controversial. The present study utilized mouse-tracking technology to examine differences in transposed-character effect substituted-character during four-character Chinese between prelingually adults (PDAs) their counterparts. PDAs were found experience greater difficulties...
Groundwater quality is strongly compromised by polluted surface water recharge in rapidly developing urban regions. However, gaps still remain the understanding of critical contaminants controlling and...
Abstract Tertiary lymphoid structures (TLS) are lymph node-like that form in response to inflammation and facilitate immune activation within the local microenvironment. TLS prevalence solid tumors has been associated with more favorable prognosis checkpoint inhibitors, findings have led hypothesis inducing formation significant therapeutic potential. Lymphotoxin beta receptor (LTBR) is a member of tumor necrosis factor (TNF) superfamily activated upon binding lymphotoxin αββ (LTαββ) or...
Benzene, a known occupational and environmental contaminant, has been recognized as the hematotoxin human carcinogen. Lipids have variety of important physiological functions abnormal lipid metabolism reported to be closely related occurrence development many diseases. In present study, we aim utilize LC-MS/MS lipidomic platform identify novel biomarkers provide scientific clues for mechanism study benzene hematotoxicity. Results showed that total 294 differential metabolites were obtained...
Abstract The kidney is the target of acute toxicity depleted uranium (DU). However, mechanism DU‐induced cytotoxicity not clear. study was to demonstrate role autophagy in and determine potential mechanism. We confirmed that after a 4‐h exposure DU, autophagic vacuoles marker light chain 3‐II human embryonic 293 cells (HEK293) increased, decreased by abrogation excessive using inhibitor. also found activation nucleus p53 inhibiting mTOR pathways DU‐treated HEK293 cells. Meanwhile,...
Abstract Background: Myeloid immune suppression in the tumor microenvironment is known to contribute evasion. ILT2 (aka LILRB1) and ILT4 LILRB2) are distinct ITIM-containing immunosuppressive receptors that recognize shared MHC-I ligands. Both highly expressed on infiltrating myeloid cells, while also tumor-associated T NK cells. Furthermore, both upregulated patients who do not respond cell checkpoint inhibitor therapy, implicating these as potential resistance mechanisms. Given their...