A5022634906- Musculoskeletal pain and rehabilitation
- Pain Mechanisms and Treatments
- Pain Management and Placebo Effect
- Mental Health Research Topics
- Heart Rate Variability and Autonomic Control
- Fibromyalgia and Chronic Fatigue Syndrome Research
- EEG and Brain-Computer Interfaces
- Neural and Behavioral Psychology Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Spine and Intervertebral Disc Pathology
- Psychosomatic Disorders and Their Treatments
- Cardiac Health and Mental Health
- Intensive Care Unit Cognitive Disorders
- Electromagnetic Fields and Biological Effects
- Noise Effects and Management
- Shoulder Injury and Treatment
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Impact of Technology on Adolescents
- Schizophrenia research and treatment
- Digital Mental Health Interventions
- Child Development and Digital Technology
- Dementia and Cognitive Impairment Research
- Media Influence and Health
- Attention Deficit Hyperactivity Disorder
Maastricht University
2014-2025
Maastricht University Medical Centre
2008-2023
University Medical Center Utrecht
2017
European Graduate School of Neuroscience
2012
Roessingh Research and Development
1999-2011
University of Twente
2002
Tilburg University
2001
St. Antonius Ziekenhuis
1996
Transnational University Limburg
1995
Introduction: White noise speech illusions index liability for psychotic disorder in case-control comparisons. In the current study, we examined i) rate of white siblings patients with and ii) to what degree this would be contingent on exposure known environmental risk factors (childhood adversity recent life events) level endophenotypic dimensions [psychotic experiences assessed Community Assessment Psychic Experiences (CAPE) scale cognitive ability]. Methods: The task was used as an...
Abstract Although case histories of depression preceding Parkinson's disease (PD) point to a possible pathophysiological relationship between these two disorders, there is as yet no epidemiological evidence support this view. We compared the incidence in patients later diagnosed with PD that matched control population. Using data from an ongoing general practice‐based register study, lifetime depressive disorder was calculated for until their diagnosis and population same register. At time...
Radiofrequency facet joint denervation procedures have been common practice for 2 decades in treatment of chronic low back pain. We designed this multicenter, randomized, double-blind, sham controlled trial to determine the efficacy radiofrequency denervation, as it is routinely performed.Inclusion criteria were pain, duration more than 6 months, and >or=50% Visual Analog Scale (VAS) reduction on diagnostic block. Exclusion prior treatment, radicular syndrome, coagulopathies, specific...
The aim of this study was to detect behavioral subsyndromes the 12-item Neuropsychiatric Inventory (NPI). Cross-sectional data 199 patients with dementia living in community were collected. Principal component analysis (with Varimax rotation) used for factor analysis. Results showed presence three subsyndromes: mood/apathy, psychosis, and hyperactivity. Anxiety regarded as a separate symptom. subsyndrome mood/apathy most common, occurring almost 80% patients, versus psychosis hyperactivity,...
Background: Reports in the literature on effects of behavioral problems patients with dementia decision to institutionalize patient have shown conflicting results. Few studies taken into account possibility that specific may differential patient. Moreover, it is probably not behavior itself causes nursing home placement (NHP), but caregivers’ emotional reaction it. The aim present study was examine impact subsyndromes and NHP. Methods: A total 119 their informal caregivers were followed up...
This study examines cortisol profiles in caregivers of dementia patients and their relationship to patients' behavioral problems. Salivary response awakening were measured 57 55 noncaregiver comparison subjects. Caregivers showed significantly higher levels at the time morning than did subjects, with a smaller increase after awakening. A was found high versus low psychological symptoms (BPSD). Elevated could predispose negative health consequences, BPSD greater risk.
In this study 42 chronic back pain patients participated twice in a treadmill test. During 1 of these 2 sessions, the partner was present. Walking time, intensity ratings, and heart rate were measured before after tests. From results previous studies it expected that, presence relatively solicitous spouse, would report more pain, have shorter walking exert themselves less physically. Spouse solicitousness ways: from patient's perspective as well that spouse. Results based on interpretation...
Delirium is a poor-prognosis neuropsychiatric disorder. Pediatric delirium (PD) remains understudied, particularly at pediatric intensive care units (PICU). Although the Anesthesia Emergence (PAED) scale, Rating Scale (DRS-88), and Scale-Revised (DRS-R-98) are available, none have been validated for use in PICU settings. The aim of present study was to investigate DRS/PAED instruments as diagnostic tools PD PICU.A prospective panel conducted, under circumstances routine clinical care,...
Experience of stress may lead to increased electromyography (EMG) activity in specific muscles compared a non-stressful situation. The main aim this study was develop and validate stress-EMG paradigm which single uncontrollable unpredictable nociceptive stimulus presented. EMG the trapezius response interest. In addition linear time effects, non-linear courses were also examined. Taking into account hierarchical structure dataset, multilevel random regression model applied. paradigm,...
Each of 20 consecutive patients with a history at least 1 year intractable chronic cervicobrachial pain was randomly assigned to one two treatment groups. The pretreatment investigation included three diagnostic segmental nerve blocks in each patient. patient Group received 67 degrees C radiofrequency lesion adjacent the dorsal root ganglion. II were treated an identical manner as those I, except that no actual made. Neither therapist nor aware group assignment. All questioned about their...
The aim of this study was to investigate whether a 15-minute placement 3G dialing mobile phone causes direct changes in EEG activity compared the sham phone. Furthermore, it investigated on ear or heart would result different outcomes. Thirty-one healthy females participated. All subjects were measured twice: one two days attached ear, other day chest. In single-blind, cross-over design, assessments condition conducted directly preceding and following exposure. During each assessment,...
Abstract Background Retrospective questionnaires are frequently used for symptom assessment in irritable bowel syndrome ( IBS ) patients, but influenced by recall bias and circumstantial psychological factors. These limitations may be overcome random, repeated, momentary during the day, using electronic Experience Sampling Methodology ESM ). Therefore, we compared to retrospective paper patients. Methods Twenty‐six patients (Rome III) were included, of which 16 diagnosed with panic disorder...
Routine Outcome Monitoring (ROM) should provide a dynamic, within-treatment forward feedback loop to guide individual treatment decisions across diagnostic categories. It has been suggested that the Experience Sampling Method (ESM), capturing film of daily life adaptive processes, offers flexible, personalised and transdiagnostic system for monitoring adapting strategies. This is first study uses an ESM application (the PsyMate™) as routine mobile-ROM (mROM) tool in ambulatory mental health...
Research suggests that the COMT Val(158)Met, BDNF Val(66)Met and OPRM1 A(118)G polymorphisms moderate experience of pain. In order to obtain experimental confirmation extension findings, cortical processing experimentally-induced pain was used.A sample 78 individuals with chronic low back complaints 37 healthy controls underwent EEG registration. Event-Related Potentials were measured in response electrical nociceptive stimuli moderation by assessed.Genetic variation did not have a direct...
Although fatigue is one of the most common and disabling symptoms in patients with multiple sclerosis (MS), its pathogenesis still poorly understood it difficult to treat. The aim current study was test assumptions a cognitive-behavioral model that explains physical disability MS patients, by comparing this approach more traditional biomedical approach. Structural equation modeling applied sample 262 patients. Neither cognitive-behavioral, nor showed an adequate fit our data. modification...
Abstract Despite many developments in the methods of event‐related potentials (ERPs), little attention has gone out to statistical handling ERP data. Trials are often averaged, and univariate or repeated measures analysis variance (ANOVA) used test hypotheses. The aim this study was introduce mixed regression research demonstrate advantages associated with method. Eighty‐five healthy subjects received electrical pain stimuli simultaneous electroencephalography (EEG) registration. Analyses...
Pleasure is one determinant of intrinsic motivation and yet a dimension often forgotten when promoting physical activity among the older population. In this study we investigate relation between daily activities activity, experience pleasure, interaction pleasure in lives community-dwelling adults. Participants carried hip-worn accelerometer during 30 consecutive days resulting total 320 data collection. Current location, companion each were assessed through sampling on smartphone every 1–2...
Object: To evalate the effectiveness of a radiofrequency lesion adjacent to dorsal root ganglion (RF-DRG) On consecutive group patients presemtomg wotj chronic thoracic pain. Design: Retrps[ectove stid by disinterested third party. Setting: Clinical outcome study. Patients: Forty- three with minimum 6 months unilateral segmental pain, unresponsive consercvative therapy were involved. Intervention: Patients lelected for lesionadjacent ganglionafter two or more prognostic nerve blocks had been...
In this post hoc observational study, we investigated psychological predictors of outcome after radiofrequency and injection treatments, commonly performed in the management chronic low back pain (CLBP).Data, comprising 161 patients (29 eventually lost to follow-up), were obtained from two randomized controlled trials on efficacy treatment for sciatica. Subsequently additionally treated an open prospective follow-up period. Although all groups presented a significant visual analog scale...