Nadja P. Marić
A5048963975- Schizophrenia research and treatment
- Mental Health Treatment and Access
- Mental Health and Psychiatry
- Tryptophan and brain disorders
- Child and Adolescent Psychosocial and Emotional Development
- Stress Responses and Cortisol
- Bipolar Disorder and Treatment
- Treatment of Major Depression
- Electroconvulsive Therapy Studies
- Mental Health Research Topics
- Genetic Associations and Epidemiology
- Diet and metabolism studies
- COVID-19 and Mental Health
- Hormonal Regulation and Hypertension
- Health Systems, Economic Evaluations, Quality of Life
- Functional Brain Connectivity Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Healthcare professionals’ stress and burnout
- Childhood Cancer Survivors' Quality of Life
- Long-Term Effects of COVID-19
- Bone health and osteoporosis research
- Maternal Mental Health During Pregnancy and Postpartum
- Growth Hormone and Insulin-like Growth Factors
- Personality Disorders and Psychopathology
- Retinal Diseases and Treatments
Institute of Mental Health
2019-2025
University of Belgrade
2016-2025
Univerzitetski Klinički Centar Srbije
2008-2025
Hospital Clínico Universitario de Valencia
2021-2023
Universitat de València
2021-2023
University of Novi Sad
2017-2022
Queen Mary University of London
2022
Centre for Mental Health
2022
Centar za Promociju Nauke
2005-2021
Institut za Reumatologiju
2021
This guidance paper from the European Psychiatric Association (EPA) aims to provide evidence-based recommendations on early intervention in clinical high risk (CHR) states of psychosis, assessed according EPA detection. The were derived a meta-analysis current empirical evidence efficacy psychological and pharmacological interventions CHR samples. Eligible studies had investigate conversion rate and/or functioning as treatment outcome patients defined by ultra-high basic symptom criteria....
Introduction: White noise speech illusions index liability for psychotic disorder in case-control comparisons. In the current study, we examined i) rate of white siblings patients with and ii) to what degree this would be contingent on exposure known environmental risk factors (childhood adversity recent life events) level endophenotypic dimensions [psychotic experiences assessed Community Assessment Psychic Experiences (CAPE) scale cognitive ability]. Methods: The task was used as an...
Schizophrenia is a heritable complex phenotype associated with background risk involving multiple common genetic variants of small effect and multitude environmental exposures. Early twin family studies using proxy‐genetic liability measures suggest gene‐environment interaction in the etiology schizophrenia spectrum disorders, but molecular evidence scarce. Here, by analyzing main joint associations polygenic score for (PRS‐SCZ) exposures 1,699 patients diagnosis disorders 1,542 unrelated...
Abstract Background Clinical research into the High Risk state for Psychosis (CHR‐P) has allowed primary indicated prevention in psychiatry to improve outcomes of psychotic disorders. The strategic component this approach is implementation clinical services detect and take care CHR‐P individuals, which are recommended by several guidelines. actual level worldwide not completely clear. Aim To assess global geographical distribution, core characteristics relating services; overview main...
We investigated the role of autophagy, a controlled cellular self-digestion process, in regulating survival neurons exposed to atypical antipsychotic olanzapine. Olanzapine induced autophagy human SH-SY5Y neuronal cell line, as confirmed by increase autophagic flux and presence vesicles, fusion autophagosomes with lysosomes, expression autophagy-related (ATG) genes ATG4B, ATG5, ATG7. The production reactive oxygen species, but not modulation main repressor MTOR or its upstream regulators...
Abstract Exposures constitute a dense network of the environment: exposome. Here, we argue for embracing exposome paradigm to investigate sum nongenetic “risk” and show how predictive modeling approaches can be used construct an score (ES; aggregated exposures) schizophrenia. The training dataset consisted patients with schizophrenia controls, whereas independent validation patients, their unaffected siblings, controls. Binary exposures were cannabis use, hearing impairment, winter birth,...
Background There has been almost no research into mental health services in Eastern Europe. A pathways study is a quick and useful starting point, requiring few resources. Aims To improve understanding of prior care-seeking treatment new patients seen at services. Method Pathways diagrams were drawn showing the routes for 50 eight centres. Patterns care-seeking, durations previous treatments compared ICD–10 diagnostic groups. Results The diagnoses varied according to organisation Major...
Abstract Aims Psychosis spectrum disorder has a complex pathoetiology characterised by interacting environmental and genetic vulnerabilities. The present study aims to investigate the role of gene–environment interaction using aggregate scores (polygenic risk score for schizophrenia (PRS-SCZ)) environment liability (exposome (ES-SCZ)) across psychosis continuum. Methods sample consisted 1699 patients, 1753 unaffected siblings, 1542 healthy comparison participants. Structured Interview...
First-degree relatives of patients with psychotic disorder have higher levels polygenic risk (PRS) for schizophrenia and intermediate phenotypes.We conducted, using two different samples discovery (n = 336 controls 649 siblings disorder) replication 1208 1106 siblings), an analysis association between PRS on the one hand psychopathological cognitive phenotypes other in a sample at average genetic (healthy controls) than patients). Two subthreshold psychosis phenotypes, as well standardised...
Abstract Aim The Covid-19 pandemic may be associated with an increase in mental disorders and distress. However, there are no representative studies testing the impact of stressors directly related to Covid-19. We aimed determine whether Covid-19-related were disorders, depressive anxiety symptoms second year pandemic. Method This cross-sectional observational epidemiological survey was conducted from June October 2021. interviewed a sample adult population Serbia (18–65 years) pandemic, at...
<i>Context:</i> Atypical antipsychotics (SGA) have the propensity to induce weight gain. <i>Objective:</i> The aim was evaluateearly changes in hormones involved neuroendocrine regulations (serum cortisol, growth hormone and prolactin) positive energy balance insulin, leptin ghrelin) during SGA treatment normal-weight patients with schizophrenia purpose of exploring possibility combat gain early through manipulation circulating levels. <i>Design:</i> We...
<i>Background:</i> Prolactin-raising antipsychotics, risperidone (antidopaminergic activity), may be associated with low bone mass. On the other hand, cause an increase in body weight thought to favorable for bone. <i>Objectives:</i> (1) To determine remodeling parameters and mass patients schizophrenia on long-term treatment long-acting injectable (LAIR) naturalistic settings, (2) evaluate change weight, metabolic profile neuroendocrine status these patients....
Abstract Background Depression is the most common mood disorder in elderly people and one of prevalent comorbidities older with hip fracture. While several authors have confirmed that depressive symptoms assessed at a later stage after fracture impact functional outcome mortality, role identified an earlier remains understudied. The aim present study was to determine if on hospital admission early surgery. Methods We studied 112 patients who underwent surgery for during 6‐month period....
Abstract Background There is evidence that environmental and genetic risk factors for schizophrenia spectrum disorders are transdiagnostic mediated in part through a generic pathway of affective dysregulation. Methods We analysed to what degree the impact polygenic (PRS-SZ) childhood adversity (CA) on psychosis outcomes was contingent co-presence dysregulation, defined as significant depressive symptoms, (i) NEMESIS-2 ( n = 6646), representative general population sample, interviewed four...