A5100717644- GaN-based semiconductor devices and materials
- ZnO doping and properties
- Advanced Combustion Engine Technologies
- Semiconductor Quantum Structures and Devices
- Chemical Synthesis and Analysis
- Combustion and flame dynamics
- Integrated Energy Systems Optimization
- Environmental Impact and Sustainability
- Ga2O3 and related materials
- Photonic and Optical Devices
- Advanced Photocatalysis Techniques
- Advanced Battery Materials and Technologies
- Semiconductor Lasers and Optical Devices
- Probabilistic and Robust Engineering Design
- Electric Power System Optimization
- Insect and Pesticide Research
- Photovoltaic System Optimization Techniques
- Advanced Battery Technologies Research
- Metal and Thin Film Mechanics
- Energy, Environment, Economic Growth
- Biochemical and Structural Characterization
- Solar Thermal and Photovoltaic Systems
- Atmospheric chemistry and aerosols
- Gas Sensing Nanomaterials and Sensors
- Forest Insect Ecology and Management
Tsinghua University
2013-2024
State Key Joint Laboratory of Environment Simulation and Pollution Control
2023-2024
Beijing University of Technology
2021-2024
North China Electric Power University
2023-2024
East China University of Science and Technology
2015-2024
Southeast University
2022-2024
Beijing Microelectronics Technology Institute
2024
Beijing University of Posts and Telecommunications
2024
China Aerospace Science and Technology Corporation
2024
Beijing Fengtai Hospital
2024
Coming together: A generally applicable strategy for convergent chemical synthesis of proteins from multiple peptide segments is developed on the basis ligation hydrazides. The hydrazide intermediates can be made at low cost and new used in 142 residue model protein RpS25 six segments. PG=protecting group.
Fully unprotected peptide o-aminoanilides can be efficiently activated by NaNO2 in aqueous solution to furnish thioesters for use native chemical ligation. This finding enables the convergent synthesis of proteins from readily synthesizable as a new type crypto-thioesters. The practicality this approach is shown histone H2B five segments. Purification or solubilization tags, which are sometimes needed improve efficiency protein synthesis, incorporated into o-aminoanilide moiety, demonstrated...
Two light-emitting diode samples are grown with InGaN and GaN underlying layers beneath the multiple quantum wells (MQWs), respectively. By measuring carrier lifetime as a function of photon energy, it is found that MQW layer has higher degree localization. Comparison between external efficiency injection current these two reveals droop at small attributed to delocalization carriers, while further due mostly leakage demonstrated through temperature-dependent electroluminescence measurements.
Racemic or quasi-racemic crystallography recently emerges as a useful technology for solution of the crystal structures biomacromolecules. It remains unclear to what extent biomacromolecules opposite handedness can differ from each other in racemic crystallography. Here we report finding that monomeric d-ubiquitin (Ub) has propensity cocrystallize with different dimers, trimers, and even tetramer l-Ub. In these cocrystals unconnected d-Ubs self-assemble form pseudomirror images oligomers...
Abstract Spintronic device is the fundamental platform for spin-related academic and practical studies. However, conventional techniques with energetic deposition or boorish transfer of ferromagnetic metal inevitably introduce uncontrollable damage undesired contamination in various spin-transport-channel materials, leading to partially attenuated widely distributed spintronic performances. These issues will eventually confuse conclusions studies limit applications spintronics. Here we...
A carrier rate model taking delocalization into account is presented to analyze current dependent internal quantum efficiency of InGaN based light-emitting diodes (LEDs). By fitting normalized experimental efficiency-current curves, both injection and radiative recombination depending on can be obtained. Based the results from two LED samples with without interlayer beneath active regions 5 wells (QWs), leakage are believed lead droop effect under considerable even larger injection,...
Rasche Vereinigung: Eine allgemein anwendbare Strategie für die konvergente chemische Synthese von Proteinen aus Peptidsegmenten wurde entwickelt. Die Peptidhydrazid-Zwischenstufen können kostengünstig hergestellt werden, und neue zur des 142 Aminosäuren langen Modellproteins RpS25 sechs eingesetzt. PG=Schutzgruppe. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available...
The construction of mirror-image biological systems may open the next frontier for biomedical technology development and discovery. Here we have designed chemically synthesized a mutant version thermostable Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) consisting d-amino acids. With total peptide length 358 amino acid residues, it is largest protein reported to date. We show that d-polymerase able amplify 120-bp l-DNA sequence coding Escherichia coli 5S ribosomal RNA gene rrfB by chain...
Abstract Polymerase chain reaction (PCR) has been a defining tool in modern biology. Towards realizing mirror-image PCR, we have designed and chemically synthesized mutant version of the 352-residue thermostable Sulfolobus solfataricus P2 DNA polymerase IV with l -amino acids tested its PCR activity biochemically. To best our knowledge, this enzyme is largest protein reported to date. We show that optimization conditions, fully synthetic capable amplifying template sequences up 1.5 kb. The...