A5091207420- Long-Term Effects of COVID-19
- Homelessness and Social Issues
- Mental Health Treatment and Access
- Chronic Obstructive Pulmonary Disease (COPD) Research
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Climate Change and Health Impacts
- Cytomegalovirus and herpesvirus research
- Viral gastroenteritis research and epidemiology
- COVID-19 epidemiological studies
- Health disparities and outcomes
- Urban Heat Island Mitigation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- COVID-19 and Mental Health
- Mitochondrial Function and Pathology
- Intensive Care Unit Cognitive Disorders
- Virology and Viral Diseases
- Urban Green Space and Health
- Migration, Health and Trauma
- Vaccine Coverage and Hesitancy
- Disaster Response and Management
- Pharmaceutical Practices and Patient Outcomes
- COVID-19 Clinical Research Studies
- Safe Handling of Antineoplastic Drugs
- Adolescent Sexual and Reproductive Health
Columbia University
2022-2025
Coconino Community College Foundation
2022
University of Arizona
2017-2021
Dermatology Research Center
2021
Arizona Department of Health Services
2017
Maricopa County Department of Public Health
2017
National Center for Immunization and Respiratory Diseases
2017
Rationale: Cigarette smoke (CS) inhalation triggers oxidative stress and inflammation, leading to accelerated lung aging, apoptosis, emphysema, as well systemic pathologies. Metformin is beneficial for protecting against aging-related diseases. Objectives: We sought investigate whether metformin may ameliorate CS-induced pathologies of emphysematous chronic obstructive pulmonary disease (COPD). Methods: Mice were exposed chronically CS fed metformin-enriched chow the second half exposure....
Incidence estimates of post-acute sequelae SARS-CoV-2 infection, also known as long-COVID, have varied across studies and changed over time. We estimated long-COVID incidence among adult pediatric populations in three nationwide research networks electronic health records (EHR) participating the RECOVER Initiative using different classification algorithms (computable phenotypes). This EHR-based retrospective cohort study included patients with documented acute infection two control groups--...
To assess the association of Long COVID with housing insecurity in United States. compare prevalence 3 binary indicators between people (symptoms >3 months) and COVID-19 survivors who did not report long-term symptoms, we used survey-weighted regression models on 206,969 responses from Household Pulse Survey, a representative cross-sectional survey US households collected September 2022–April 2023. Among COVID, additionally assessed whether functional impairment, current related symptom...
Estimates of post-acute sequelae SARS-CoV-2 infection (PASC) incidence, also known as Long COVID, have varied across studies and changed over time. We estimated PASC incidence among adult pediatric populations in three nationwide research networks electronic health records (EHR) participating the RECOVER Initiative using different classification algorithms (computable phenotypes). Overall, 7% children 8.5%-26.4% adults developed PASC, depending on computable phenotype used. Excess patients...
Background Positive serology for cytomegalovirus (CMV) has been associated with all-cause mortality risk but its role in COPD is unknown. The objective of the present study was to assess relationship between CMV and mortality. Methods We analysed data from 806 participants Tucson Epidemiological Study Airway Obstructive Disease who, at enrolment, were aged 28–70 years had completed lung function tests. tested sera enrolment defined “high serology” as being highest tertile. Vital status, date...
To assess the association of Long COVID with housing insecurity in United States.
Background: There is limited understanding of the prevalence psychological distress and associated stressors supports among displaced adults in low-and middleincome first asylum countries.Method: This article reports findings a cross-sectional study.We recruited 245Congolese (18-80 years) residing Nairobi, Kenya using snowball sampling.Data were collected an interviewer-administered questionnaire consisting sociodemographic characteristics, Self-Reporting Questionnaire (SRQ-20), locally...
Genomic surveillance and wastewater tracking strategies were used to strengthen the public health response an outbreak of SARS-CoV-2 Delta AY.25 lineage associated with a university campus in Arizona. Epidemiologic clinical data routinely gathered through contact tracing matched genomes belonging identified ongoing phylogenomic analyses. Continued phylogenetic analyses conducted further describe outbreak. Wastewater collected twice weekly from sites across was tested for by RT-qPCR,...
Abstract Latent tuberculosis ( TB ) infection is routinely diagnosed using the tuberculin skin test TST ). New methods of detection more specific than such as Quanti FERON Gold In‐Tube QFT ‐ GIT have been developed but evidence remains limited on their acceptability among migrant farmworkers. This article examined screening tests farmworkers working Arizona‐Mexico border. We conducted a cross‐sectional survey via questionnaire. Of 83 participants interviewed, 53 (63.9%) believed that was...
ObjectiveUsing a syndromic surveillance system to understand the magnitude and risk factors related heat-related illness (HRI) in Pinal County, AZ.IntroductionExtreme heat is major cause of weather-related morbidity mortality United States (US).1 HRI most frequent environmental exposure-related injury treated US emergency departments.2 More than 65,000 room visits occur for acute each summer nationwide.3 In Arizona, accounts an estimated 2,000 patients 118 deaths year.4 As becomes...
Abstract Purpose To assess whether neighborhood-level measures of policing are spatio-temporally associated with psychiatric hospialization among adolescents and young adults in New York City, this association varies by neighborhood racial composition. Methods We derived population-based from the City Police Department (NYPD), hospitalization Statewide Planning Research Cooperative System (SPARCS) data, socio-demographic data American Community Survey (ACS), aggregated month ZIP Code...
ObjectiveAfter remaining stable for many years, the prevalence of depression among adolescents increased over past decade, particularly girls. In this study, we used longitudinal data from a cohort high school students to characterize sex-specific trajectories depressive symptoms during period increasing and widening gender gap in adolescent depression.MethodUsing Health Happiness Cohort, 8-wave study residing Los Angeles County 2013 2017 (N = 3,393), conducted multiple group latent class...
<b>Background:</b> An upregulation of the B cell compartment is present in COPD lungs, together with increases number cell-rich lymphoid follicles (LFs), and levels products such as Activation Factor (BAFF). We hypothesize that this exaggerated response observed associated extent computed tomography (CT)-defined emphysema independently airflow limitation thus GOLD stage. <b>Methods:</b> performed immunofluorescence stainings for cells, BAFF, CD138 (plasmacells), CD10 (immature cells), CD24...
<b>Background:</b> Positive serology for cytomegalovirus (CMV) has been associated with all-cause mortality risk in previous studies. <b>Aims:</b> We sought to determine the relation of CMV COPD mortality. <b>Methods:</b> analyzed data from 806 participants TESAOD cohort who at enrollment 1972 were aged 28–70 yrs and completed lung function tests. serum samples was categorized as low, medium, high tertiles. Date cause death assessed through certificates linkage National Death Index up...
Medication automatic dispensing systems (ADS) have been implemented in many settings, including fire-based EMS stations. The aim of this study was to evaluate the impact in-station ADSs on controlled substance administration rates and response intervals.This a retrospective review data from single agency. intervals were compared before ADS implementation (P1; 6/1/15 5/31/16) after (P3; 6/1/17-5/31/19). Cases with missing during one-year period excluded.4045 cases identified P1 8168 P3. odds...
Abstract Large scale outbreaks of the SARS-CoV-2 Delta variant have occurred in numerous settings, including universities. An outbreak AY.25 lineage associated with a university campus multiple transmission events was identified; genomic analyses characterized this and complemented contract tracing wastewater surveillance strategies that strengthened overall public health response actions. Epidemiologic clinical data routinely gathered through contact investigations were matched to...