A5009097380- Celiac Disease Research and Management
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Anorectal Disease Treatments and Outcomes
- COVID-19 Clinical Research Studies
- Higher Education Teaching and Evaluation
- Colorectal Cancer Surgical Treatments
- Lymphoma Diagnosis and Treatment
- Educational theories and practices
- Nitric Oxide and Endothelin Effects
- Pelvic floor disorders treatments
- E-Learning and Knowledge Management
- Microscopic Colitis
- Viral-associated cancers and disorders
- Immunodeficiency and Autoimmune Disorders
- Cerebrovascular and Carotid Artery Diseases
- Inflammatory Bowel Disease
- Long-Term Effects of COVID-19
- Immune Cell Function and Interaction
- COVID-19 and healthcare impacts
- Lung Cancer Treatments and Mutations
- Acute Ischemic Stroke Management
- Viral gastroenteritis research and epidemiology
- Literacy and Educational Practices
- Cardiac, Anesthesia and Surgical Outcomes
Universitat Autònoma de Barcelona
1974-2025
Centro Regional de Hemodonación
2020-2024
Hospital Moinhos de Vento
2024
Hospital de Clínicas de Porto Alegre
2024
Health and Education Research Management and Epidemiologic Services (United States)
2023
Hospital Arnau de Vilanova
2004-2021
Universidad de Valladolid
1981-2021
BioCruces Health research Institute
2021
Hospital General Universitario de Albacete
2021
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2020
<b>BACKGROUND AND PURPOSE:</b> Clot extent, location, and collateral integrity are important determinants of outcome in acute stroke. We hypothesized that a novel clot burden score (CBS) (CS) clinical radiologic outcomes serve as useful additional stroke predictors. <b>MATERIALS METHODS:</b> One hundred twenty-one patients with anterior circulation infarct presenting within 3 hours onset were reviewed. The Spearman correlation was performed to assess the between CBS CS measures. Patients...
BACKGROUND. Passive immunotherapy with convalescent plasma (CP) is a potential treatment for COVID-19. Evidence from controlled clinical trials inconclusive.
The SARS-CoV-2 infection has widely spread to become the greatest public health challenge date, COVID-19 pandemic. Different fatality rates among countries are probably due non-standardized records being carried out by local authorities. Spanish case-fatality rate is 11.22%, far higher than those reported in Asia or other European countries. A multicentre retrospective study of demographic, clinical, laboratory and immunological features 584 hospitalized patients their outcomes was...
The experience of 22 Hodgkin's disease (HD) patients with human immunodeficiency virus type I (HIV) antibodies, collected from a cooperative study six hospitals during 1984-1989 is presented. Young men (average age, 27.6 years) high incidence intravenous drug abuse (86%) were found. status the HIV infection at diagnosis HD was: four patients, acquired immune deficiency syndrome (AIDS); eight persistent generalized lymphadenopathy (PGL); and ten asymptomatic. natural history was unusual, B...
Abstract Depression is a common, severe, disabling mental disease that affects millions of people all ages worldwide. Various studies have shown neurotrophic/growth factors key role in depression and, more specifically, vascular endothelial growth factor (VEGF) implicated the pathogenesis depression. The purpose this study was to investigate potential links between four VEGF-related single-nucleotide polymorphisms (SNPs), previously identified through genome-wide association (GWAS) and...
The multidrug resistance MDR1 gene codes for a membrane transporter associated with inflammatory bowel disease. polymorphism Ala893Ser/Thr (G2677T/A) previously showed significant association Crohn's disease (CD) and the Ile1145Ile (C3435T) ulcerative colitis (UC). We studied of both polymorphisms in an independent population to reveal impact on predisposition disease.Case-control study 321 CD 330 UC white Spanish patients recruited from same center, 352 healthy ethnically matched controls.A...
<b>Objectives:</b> Expression of major histocompatibility complex (MHC) class II genes is almost exclusively regulated by the transactivator. A promoter polymorphism (−168A/G, rs3087456) in <i>MHC2TA</i> gene was associated with increased susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction a northern European population. However, no evidence association this variant two autoimmune diseases could be subsequently detected independent cohorts. <b>Aim:</b> To...
Abstract Background The coronavirus 2019 (COVID-19) pandemic is a clinical situation that could be used as prototype for implementation of new systems care. Methods This was single-center, cross-sectional study. We evaluated the feasibility strategy based on conversion face-to-face visits to telephone consultations manage IBD outpatients during COVID-19 pandemic. A 4-item survey (3 closed questions and 100-point numeric description scale) conducted evaluate satisfaction patients with...
The aim of the present study was to analyze in a series 24 HIV-positive Hodgkin's disease (HD) patients morphological and immunological features, presence rearrangements immunoglobulin heavy chain (IgH) gene, expression Epstein-Barr virus (EBV) latent membrane protein-1 (LMP-1), existence deletions intracytoplasmic domain LMP-1 gene. results obtained were compared with those from parallel 56 ordinary HD. Briefly, comparison two showed predominance unfavorable histological subtypes HD...
The participation of nitric oxide and vasoactive intestinal peptide (VIP) in the neurogenic regulation bovine cerebral arteries was investigated. Nitrergic nerve fibers ganglion-like groups neurons were revealed by NADPH-diaphorase staining adventitial layer arteries. NADPH diaphorase also present endothelial cells but not smooth muscle layer. Double immunolabeling for neuronal synthase VIP indicated that both molecules co-localized same these vessels. Transmural stimulation (200 mA, 0.2...
Aim: Human respiratory syncytial virus (HRSV) is the main cause of tract infections among infants. Materials & methods: In present study, molecular epidemiology HRSV detected from 2013 to 2017 has been described. Results: A 10% collected samples were laboratory confirmed for HRSV. Patients under 2 years age susceptible population disease, but an increasingly number patients over 65 was reported. Epidemics usually started in autumn and ended spring. Both groups co-circulated every season,...
Abstract Background Porcine reproductive and respiratory syndrome virus (PRRSV) persists on certain farms despite vaccination control efforts, with genetic diversity suspected as a contributing factor. This study examined the evolution persistence dynamics of PRRSV-1 farrow-to-fattening farm 1,700 sows vaccinated quarterly, focusing summer lapse. Results Over eight months, three farrowing batches were monitored from birth to nine weeks age using virological (RT-qPCR, whole-genome, ORF5...
To investigate the contribution of multidrug resistance 1 (MDR1) gene pharmacogenetics (G2677T/A and C3435T) to efficacy azathioprine in inducing remission patients with Crohn's disease (CD). A cohort 327 unrelated Spanish CD recruited from a single center was studied. All were rigorously followed up for at least 2 years (mean time, 11.5 years). case-control analysis MDR1 G2677T/A C3435T SNPs loci haplotypes 112 steroid-dependent treated performed. Patients classified on basis response...
Candida albicans is an opportunistic fungal pathogen that infects immunocompromised patients. Infection control requires phagocytosis by innate immune cells, including macrophages. Migration towards, and subsequent recognition of, C. cell wall components macrophages critical for phagocytosis. Using live-cell imaging of phagocytosis, the macrophage line J774.1 showed enhanced movement in response to mutants, particularly during first 30 min, irrespective infection ratio. However, phagocyte...