A5060958743- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Pharmaceutical and Antibiotic Environmental Impacts
- Infections and bacterial resistance
- Evolution and Genetic Dynamics
- Bacterial Genetics and Biotechnology
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Bacteriophages and microbial interactions
- Vibrio bacteria research studies
- Bacterial Identification and Susceptibility Testing
- Gut microbiota and health
- Genomics and Phylogenetic Studies
- Clostridium difficile and Clostridium perfringens research
- Antimicrobial agents and applications
- Antimicrobial Resistance in Staphylococcus
- Plant Pathogenic Bacteria Studies
- Escherichia coli research studies
- Ultrasound in Clinical Applications
- Antimicrobial Peptides and Activities
- Probiotics and Fermented Foods
- Pneumonia and Respiratory Infections
- Salmonella and Campylobacter epidemiology
- Microbial Community Ecology and Physiology
- Aquaculture disease management and microbiota
Centro Nacional de Biotecnología
2016-2025
Consejo Superior de Investigaciones Científicas
2014-2024
Technical University of Denmark
2015-2024
University of Wisconsin–Madison
2024
Universidad del Desarrollo del Estado de Puebla
2023
International Flavors & Fragrances (France)
2023
Centro de Investigación Biomédica en Red
2008-2022
Hospital Universitario Puerta de Hierro Majadahonda
1999-2022
Instituto de Investigación Sanitaria de Santiago
2022
Hospital Universitario Ramón y Cajal
1989-2020
OPINION article Front. Microbiol., 13 January 2012Sec. Antimicrobials, Resistance and Chemotherapy Volume 3 - 2012 | https://doi.org/10.3389/fmicb.2012.00001
The large majority of antibiotics currently used for treating infections and the antibiotic resistance genes acquired by human pathogens each have an environmental origin. Recent work indicates that function these elements in their reservoirs may be very distinct from "weapon-shield" role they play clinical settings. Changes natural ecosystems, including release amounts antimicrobials, might alter population dynamics microorganisms, selection resistance, with consequences health are...
It has been widely assumed that the ecological function of antibiotics in nature is fighting against competitors. This made them a good example Darwinian struggle-for-life microbial world. Based on this idea, it also believed antibiotics, even at subinhibitory concentrations, reduce virulence bacterial pathogens. Herein, using combination genomic and functional assays, we demonstrate specific (namely tobramycin, tetracycline, norfloxacin) concentrations trigger expression determinants...
A comprehensive monitoring of a broad set antibiotics in the final effluent wastewater treatment plants (WWTPs) 7 European countries (Portugal, Spain, Ireland, Cyprus, Germany, Finland, and Norway) was carried out two consecutive years (2015 2016). This is first study this kind performed at an international level. Within 53 monitored 17 were detected least once WWTPs, i.e.: ciprofloxacin, ofloxacin, enrofloxacin, orbifloxacin, azithromycin, clarithromycin, sulfapyridine, sulfamethoxazole,...
The antibiotic resistome in European UWTPs mirrors the gradient of north-to-south clinical resistance prevalence.
Bacteria with intrinsic resistance to antibiotics are a worrisome health problem. It is widely believed that antibiotic of bacterial pathogens mainly the consequence cellular impermeability and activity efflux pumps. However, analysis transposon-tagged Pseudomonas aeruginosa mutants presented in this article shows phenotype emerges from action numerous proteins all functional categories. Mutations some genes make P. more susceptible thereby represent new targets. other resistant therefore...
Multidrug efflux pumps are chromosomally encoded genetic elements capable of mediating resistance to toxic compounds in several life forms. In bacteria, these involved intrinsic and acquired antibiotics. Unlike other well-known horizontally antibiotic determinants, genes encoding for multidrug belong the core bacterial genomes thus have evolved over millions years. The selective pressure stemming from use antibiotics treat infections is relatively recent evolutionary terms. Therefore, it...
Anthropogenic environments have been implicated in enrichment and exchange of antibiotic resistance genes bacteria. Here we study the impact confined controlled swine farm on temporal changes gut microbiome resistome veterinary students with occupational exposure for 3 months. By analyzing 16S rRNA whole metagenome shotgun sequencing data tandem culture-based methods, show that shapes students, resulting potentially pathogenic taxa antimicrobial genes. Comparison students' microbiomes...