Jaclyn Bennet
A5048354717- HIV/AIDS drug development and treatment
- Pneumonia and Respiratory Infections
- Tuberculosis Research and Epidemiology
- HIV-related health complications and treatments
- Liver Disease Diagnosis and Treatment
- HIV/AIDS Research and Interventions
- Hepatitis C virus research
- COVID-19 Clinical Research Studies
- Hepatitis B Virus Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Brain Metastases and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- SARS-CoV-2 and COVID-19 Research
- Neurological Complications and Syndromes
- Health Systems, Economic Evaluations, Quality of Life
- Drug-Induced Adverse Reactions
- Chronic Lymphocytic Leukemia Research
- Infectious Diseases and Tuberculosis
- Pharmacological Effects and Toxicity Studies
- Lymphoma Diagnosis and Treatment
- Neurological Disorders and Treatments
- HIV Research and Treatment
- Venous Thromboembolism Diagnosis and Management
- Pulmonary Hypertension Research and Treatments
- Immunodeficiency and Autoimmune Disorders
University of the Witwatersrand
2020-2025
Helen Joseph Hospital
2024
The Phase 3 randomized controlled trial, TBTC Study 31/ACTG A5349 (NCT02410772) demonstrated that a 4-month rifapentine-moxifloxacin regimen for drug-susceptible pulmonary tuberculosis was safe and effective. primary efficacy outcome 12-month disease free survival, while the safety proportion of grade or higher adverse events during treatment period. We conducted an analysis demographic, clinical, microbiologic, radiographic, pharmacokinetic data identified risk factors unfavorable outcomes...
Abstract Background Patterns of antiretroviral therapy (ART) use and immunologic correlates vary globally, contemporary trends are not well described. Methods The REPRIEVE trial (Randomized Trial to Prevent Vascular Events in HIV) enrolled persons with human immunodeficiency virus (HIV) who were aged 40–75 years, receiving ART, had low-to-moderate cardiovascular disease risk. ART was summarized within Global Burden Disease (GBD) super-regions, adjusted linear logistic regression analyses...
Abstract Understanding of pandemics depends on the characterization pathogen collections from well-defined and demographically diverse cohorts. Since its emergence in Congo almost a century ago, Human Immunodeficiency Virus Type 1 (HIV-1) has geographically spread genetically diversified into distinct viral subtypes. Phylogenetic analysis can be used to reconstruct ancestry virus better understand origin distribution We sequenced two 3.6-kb amplicons HIV-1 genomes 3,197 participants clinical...
BACKGROUND: Spirometry is considered relevant for the diagnosis and monitoring of post-TB lung disease. However, spirometry rarely done in newly diagnosed TB patients. METHODS: Newly diagnosed, microbiologically confirmed patients were recruited study. was performed within 21 days treatment initiation according to American Thoracic Society/European Respiratory Society guidelines. analysis using Global Lung Initiative equations standardisation. RESULTS: Of 1,430 eligible study participants,...
In this case report, we described a 48-year-old human immunodeficiency virus-negative man with pulmonary tuberculosis (TB) who had an incidental finding of concurrent chronic lymphocytic leukaemia. We highlighted the importance considering other differential diagnoses when patients present TB or haematological malignancies. also discussed difficulties in diagnosis both these conditions co-exist and how affected treatment management.