A5009272192- Global Cancer Incidence and Screening
- Photonic and Optical Devices
- Silk-based biomaterials and applications
- Digital Radiography and Breast Imaging
- Radiology practices and education
- Breast Cancer Treatment Studies
- Advanced Fiber Optic Sensors
- Colorectal Cancer Screening and Detection
- Microfluidic and Capillary Electrophoresis Applications
- COVID-19 and healthcare impacts
- Breast Lesions and Carcinomas
- Diabetic Foot Ulcer Assessment and Management
- Wound Healing and Treatments
- Electrowetting and Microfluidic Technologies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Nanofabrication and Lithography Techniques
- Empathy and Medical Education
- Biochemical and Structural Characterization
- Medical Image Segmentation Techniques
- Lymphadenopathy Diagnosis and Analysis
- Cancer survivorship and care
- Patient-Provider Communication in Healthcare
- Clinical Reasoning and Diagnostic Skills
- Photonic Crystal and Fiber Optics
- Optical measurement and interference techniques
University of Vermont
2020-2024
University of Vermont Medical Center
2018-2023
Beth Israel Deaconess Medical Center
2018-2019
Tufts University
2006-2009
Regular nanometer-scale patterning down to a few tens of nanometers and the manufacturing diffractive optical elements in silk by using ideas soft lithography is reported. The unique processing films makes them an ideal substrate incorporate biological matter (such as small organics, enzymes, proteins, cells). Unprecedented definition transverse direction, with features nanometers,
We demonstrate controllable structural color based on periodic nanopatterned 2D lattices in pure protein films of silk fibroin. show here fibroin with feature sizes hundreds nanometers that exhibit different colors as a function varying lattice spacing. Further, when the index refraction contrast between and its surrounding environment by applying liquids top lattices, colorimetric shifts are observed. The effect is characterized experimentally theoretically simple example glucose...
Free-standing silk films are useful materials to manufacture nanopatterned optical elements and immobilize bio-dopants such as enzymes while maintaining their biological activity. These traits were combined by incorporating hemoglobin into free-standing diffraction gratings fabricate chemically responsive optofluidic devices ambient gas conditions, constituting a simple oxygen sensor. This type of self-analyzing system is enabled the unique ability reproduce high-fidelity structures in...
Background It is unclear whether breast US screening outcomes for women with dense breasts vary levels of cancer risk. Purpose To evaluate female patients and different estimated risk levels. Materials Methods This retrospective observational study used data from examinations in heterogeneously or extremely conducted January 2014 to October 2020 at 24 radiology facilities within three Breast Cancer Surveillance Consortium (BCSC) registries. The primary were the detection rate, false-positive...
Abstract Background There are no consensus guidelines for supplemental breast cancer screening with whole‐breast ultrasound. However, criteria women at high risk of mammography failures (interval invasive or advanced cancer) have been identified. Mammography failure was evaluated among undergoing ultrasound in clinical practice compared alone. Methods A total 38,166 ultrasounds and 825,360 mammograms without were identified during 2014–2020 within three Breast Cancer Surveillance Consortium...
Purpose To evaluate long-term trends in mammography screening rates and identify sociodemographic breast cancer risk characteristics associated with return to after the COVID-19 pandemic. Materials Methods In this retrospective study, statewide data of 222 384 female individuals aged 40 years or older (mean age, 58.8 ± 11.7 [SD]) from Vermont Breast Cancer Surveillance System were evaluated generate descriptive statistics Joinpoint models characterize patterns during 2000–2022. Log-binomial...
1. Rates of protein synthesis and catabolism were measured in longissimus dorsi hind-limb muscles suckling piglets. 2. Half-lives for mixed sarcoplasmic proteins 4.8 9.4 d respectively. The corresponding values myofibrillar 5.7 16.4 d. 3. half-lives significantly different from those not confounded by contamination the fraction with plasma higher specific activity. 4. Individual synthesized catabolized at rates which statistically different. Intramuscular connective tissue also appeared to...
Background Established mammography screening performance metrics use the initial assessment because they were developed for radiologist auditing, yet these are frequently used to inform health policy and decision making. The authors have new based on final that consider entire episode, including diagnostic workup. Methods data from 2,512,577 episodes during 2005‐2017 at 146 facilities in United States participating Breast Cancer Surveillance Consortium. Screening of episode compared with...
This article presents a simple and novel method for the fabrication of cylindrical microchannels in polymer or biopolymer substrates. process results highly regular, microchannels, suitable both to transport liquid transmission light. eliminates issues associated with positioning tolerances characteristic conventional techniques, such as soft lithography. Such devices hold great promise field biomedical engineering by providing true profile microflow studies vascular modeling, well ability...
We demonstrate an optofluidic lab-on-a-chip device by fabricating optical transmission grating with integrated microfluidic channel using soft lithography in polydimethylsiloxane. This integration of functionalities provides spectral analysis ldquoon-chiprdquo the contents channel. this functionality performing a chlorophyll probed visible supercontinuum light. The has resolving power 330 and works over wavelength range.
Abstract Traditional score-based peer review has come under scrutiny in recent years, as studies have demonstrated it to be generally ineffective at improving quality. Many practices and programs are transitioning a learning model replace or supplement traditional review. Peer differs from that the emphasis is on sharing opportunities creating an environment fosters discussion of errors nonpunitive forum with goal improved patient care. Creating just culture central fostering successful...
Abstract Objective Evaluate women’s anxiety and experience undergoing screening mammography during the COVID-19 pandemic. Methods An IRB-approved anonymous survey was administered to women receiving across six sites in U.S. Singapore from October 7, 2020, March 11, 2021. Using a 1–5 Likert scale, rated their pre- post-visit regarding having mammogram pandemic, importance of observed precautions, personal risk factors for breast cancer severe illness. Post-visit change evaluated....
Background: Suprasorb Liquacel Pro (standard test dressing) and Ag (test dressing with silver nanoparticles) are absorptive gelling-fibre dressings designed to manage wound exudate levels promote moist healing, the latter having additional antimicrobial properties. Aims: To assess impact of on signs infection. Methods: Patients moderately-to-highly exuding hard-to-heal wounds any type were dressed standard or nanoparticles if they showed covert overt local Comparative data collected at...
We explore the possibility of using optical tweezers to enable all control optofluidic circuits. Optically trapped microspheres can be used as microlenses for signal switching and steering. By cantilevers instead we provide a method robust stable placement elements in Cantilevers made tapered fiber polydimethyl siloxane are demonstrated. also show that it is possible use transverse tweezer beams load silica beads into hollow core photonic crystal fibers tuning their transmission properties.
Abstract Whether beginning a new career in breast imaging or switching into different practice for personal professional advancement, leadership opportunity, need to relocate geographically, simply better it is critical transition between positions as smoothly possible. Thoroughly reflecting on your priorities and goals essential prior undertaking any transition. Once the decision has been made move position, imperative learn about dynamics of environment. Here, we provide suggestions how...