Zhaohuan Li

ORCID: 0000-0001-8902-0320
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About
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Nuclear Physics and Applications
  • Cardiovascular Disease and Adiposity
  • Nuclear reactor physics and engineering
  • Biocrusts and Microbial Ecology
  • Cardiac Valve Diseases and Treatments
  • Nanoplatforms for cancer theranostics
  • Coronary Interventions and Diagnostics
  • Nanoparticle-Based Drug Delivery
  • Advanced MRI Techniques and Applications
  • Algal biology and biofuel production
  • Ultrasound Imaging and Elastography
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiovascular Health and Disease Prevention
  • Advanced X-ray and CT Imaging
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Microbial Community Ecology and Physiology
  • Multiple Myeloma Research and Treatments
  • Ultrasound and Hyperthermia Applications
  • RNA Interference and Gene Delivery
  • Graphite, nuclear technology, radiation studies
  • Cancer Mechanisms and Therapy
  • Urban Design and Spatial Analysis
  • Liver physiology and pathology

University of Electronic Science and Technology of China
2020-2024

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2015-2023

University of Pennsylvania
2021-2023

Changsha Central Hospital
2023

University of South China
2023

Weifang Medical University
2020-2022

Weifang University
2021

University of Chinese Academy of Sciences
2019-2020

Chinese Academy of Sciences
2019-2020

Northwest Institute of Eco-Environment and Resources
2019-2020

The occurrence and distribution of 20 subtypes antibiotic resistance genes (ARGs), conferring sulfonamide, tetracycline, macrolide, β-lactam, aminoglycoside, or quinolone resistance, were investigated in urban dust samples collected from the surfaces three megacities (Beijing, Tianjin, Shijiazhuang) northern China. Real-time polymerase chain reaction indicated that abundance ARGs 16S rRNA was significantly higher summer than winter. A total 80 antibiotic-resistant bacteria isolated...

10.1021/acs.estlett.7b00571 article EN Environmental Science & Technology Letters 2018-01-25

Hypertrophic cardiomyopathy (HCM) is characterized by increased left ventricular wall thickness, cardiomyocyte hypertrophy, and fibrosis. Adverse cardiac risk characterization has been performed using late gadolinium enhancement (LGE), native T1, extracellular volume (ECV). Relaxation time constants are affected background field inhomogeneity. T1ρ utilizes a spin-lock pulse to decrease the effect of unwanted relaxation. The objective this study was as compared ECV, LGE in HCM patients....

10.1186/s12968-021-00813-5 article EN cc-by Journal of Cardiovascular Magnetic Resonance 2021-03-01

Background: Tumor angiogenesis has been proven to potentiate tumor growth and metastasis; therefore, the strategies targeting tumor-related have great potentials in antitumor therapy. Methods: Here, GA&Gal dual-ligand-modified liposomes co-loaded with curcumin combretastatin A-4 phosphate (CUCA/GA&Gal-Lip) were prepared characterized. A novel “BEL-7402+HUVEC” co-cultured cell model was established mimic microenvironment. The cytotoxicity migration assays performed against model. Angiogenesis...

10.2147/ijn.s309804 article EN cc-by-nc International Journal of Nanomedicine 2021-06-01

Desertification and water body eutrophication are two severe environmental problems worldwide. To alleviate these simultaneously, a new idea, introducing aquatic cyanobacteria (AC) from Lake Chaohu to the surface of Tengger Desert encourage growth biological soil crusts, was proposed. A network-structured nanocomposite (SXA) consisting sodium polyacrylate (SP), xanthan gum (XG), attapulgite (ATP) also fabricated. The SXA showed high water-retention ability, viscosity, biosafety could provide...

10.1021/acssuschemeng.0c00233 article EN ACS Sustainable Chemistry & Engineering 2020-02-20

IRI&398-s-LPs was destroyed in the TME, leading to rapid release of drugs, thus killing tumor cells and CAFs simultaneously. The combinational strategy by eliminating both “seeds” “soil” is beneficial for enhancing antitumor effect.

10.1039/d1nr01506k article EN Nanoscale 2021-01-01

Qualitative myocardial perfusion (QMP) derived from contrast echocardiography reflects the capillary flow, while coronary flow velocity reserve Doppler spectrum (D-CFVR) of left anterior descending artery (LAD) is used to assess microvascular function, particularly after excluding severe epicardial stenosis. The present study aimed relationship QMP and D-CFVR in detecting disease (CMVD) by using adenosine triphosphate stress (ATP MCE).

10.3389/fcvm.2024.1353736 article EN cc-by Frontiers in Cardiovascular Medicine 2024-09-23

Carotid atherosclerosis plaque rupture is an important cause of myocardial infarction and stroke. The effective segmentation ultrasound images carotid atherosclerotic plaques aids clinicians to accurately assess stability. At present, this procedure relies mainly on the experience medical practitioner manually segment image plaque. This method also time-consuming.This study intends establish automatic intelligent plaque.The present combined U-Net DenseNet networks, automatically plaques....

10.3233/thc-220152 article EN Technology and Health Care 2022-08-09

Antinuclear antibodies (ANAs) testing is the main serological diagnosis screening test for autoimmune diseases. ANAs conducted principally by indirect immunofluorescence (IIF) on human epithelial cell-substrate (HEp-2) protocol. However, due to its high variability and subjectivity, there an insistent need develop efficient method automatic image segmentation classification. This article develops classification framework based artificial intelligence (AI) ANA images. The Otsu thresholding...

10.1155/2023/1353965 article EN Computational Intelligence and Neuroscience 2023-02-08

Diabetes mellitus (DM) is a chronic disease that poses serious risk of cardiovascular diseases. Therefore, early detection impaired cardiac function with non-invasive myocardial imaging critical for improving the prognosis patients DM.This study aimed to assess left ventricular (LV) in type 2 diabetes (T2DM) by work technique.In all, 67 T2DM and 28 healthy controls were included divided into DM group control group. Two-dimensional dynamic images apical three-chamber view, two-chamber...

10.3389/fendo.2023.1241307 article EN cc-by Frontiers in Endocrinology 2023-09-05

To evaluate the left ventricular energy loss (EL), reserve (EL-r), and rate in patients with mild coronary artery stenosis by using vector flow mapping (VFM) combined exercise stress echocardiography.A total of 34 (case group) 36 sex age matched (control without according to angiogram were prospectively enrolled. The (ELt), basal segment (ELb), middle (ELm), apical (ELa), recorded isovolumic systolic period (S1), rapid ejection (S2), slow (S3), diastolic (D1), filling (D2), (D3), atrial...

10.1111/echo.15591 article EN cc-by-nc-nd Echocardiography 2023-05-13

We aimed to quantitatively analyze wall shear stress (WSS) of the common carotid artery (CCA) and elucidate relationship between WSS cardiovascular disease (CVD) in patients with type 2 diabetes mellitus (T2DM) using ultrasound vector flow (V-Flow) imaging.

10.3389/fendo.2024.1409082 article EN cc-by Frontiers in Endocrinology 2024-11-21
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