A5024893480- Ocular Infections and Treatments
- Antifungal resistance and susceptibility
- Ocular Surface and Contact Lens
- Plant Pathogens and Fungal Diseases
- Ocular Diseases and Behçet’s Syndrome
- Essential Oils and Antimicrobial Activity
- Antimicrobial Peptides and Activities
- Fungal Infections and Studies
- Enzyme-mediated dye degradation
- Biochemical and Structural Characterization
- Antimicrobial Resistance in Staphylococcus
- Infectious Diseases and Mycology
- Mycobacterium research and diagnosis
- Microbial Natural Products and Biosynthesis
- Microbial Metabolism and Applications
- Entomopathogenic Microorganisms in Pest Control
- Environmental Toxicology and Ecotoxicology
- Actinomycetales infections and treatment
- Medicinal Plant Research
- Plant chemical constituents analysis
- Plant and fungal interactions
- Natural product bioactivities and synthesis
- Nematode management and characterization studies
- Plant-based Medicinal Research
- Bacterial biofilms and quorum sensing
PSG INSTITUTE OF TECHNOLOGY AND APPLIED RESEARCH
2015-2024
Coimbatore Medical College and Hospital
2013-2014
Fungal aetiology of keratitis/corneal ulcer is considered to be one the leading causes ocular morbidity, particularly in developing countries including India. More importantly, Fusarium and Aspergillus are reported commonly implicating corneal against this background present work was undertaken so as understand current epidemiological trend two fungal keratitis. During project period, a total 500 scrapings were collected from suspected mycotic keratitis patients, which 411 (82.2%) culture...
Seventy Fusarium isolates derived from human keratomycosis were identified based on partial sequences of the β-tubulin (β-TUB) and translation elongation factor 1α (EF-1α) genes. Most confirmed as members F. solani species complex (75.71%), followed by dimerum (8.57%), fujikuroi oxysporum (4.29%) incarnatum-equiseti (2.86%). A combined phylogenetic tree was estimated including all 70 isolates. Isolates belonging to different complexes formed separate clades. In this study, we also report...
Summary In recent years, Aspergillus species are reported frequently as aetiological agents of fungal keratitis in tropical countries such India. Our aim was to evaluate the epidemiological features cases over a 3‐year period tertiary eye care hospital and determine antifungal susceptibilities causative agents. This study included culture proven diagnosed between September 2005 August 2008. Data including prevalence, predisposing factors demography were recorded, isolates identified by...
Fusarium species are reported frequently as the most common causative agents of fungal keratitis in tropical countries such India. Sixty-five fusaria isolated from patients were subjected to multilocus DNA sequencing characterize spectrum associated with infections Susceptibilities these ten antifungals determined vitro by broth microdilution method. An impressive phylogenetic diversity was reflected susceptibilities differing at level. Typing results revealed that isolates distributed among...
Aspergillus tamarii appears to be an emerging aetiological agent of human keratomycoses in South India. The investigated strains were isolated from six suspected fungal keratitis patients attending a tertiary care eye hospital Coimbatore (Tamil Nadu, India), and initially identified by the microscopic examinations scrapings cultures. Our data suggest that A. could easily overlooked when identification is carried out based on morphological characteristics alone, while sequence analysis...
The present study was carried out to investigate the antifungal effects of <i>Cinnamomum zeylanicum, Citrus limon, Juniperus communis, Eucalyptus citriodora, Gaultheria procumbens, Melaleuca alternifolia, Origanum majorana, Salvia sclarea</i>, and <i>Thymus vulgaris</i> essential oils against <i>Fusarium</i> species, most common etiologic agents filamentous fungal keratitis in South India. <i>C. zeylanicum</i> oil showed strong anti-<i>Fusarium</i> activity, whereas all other tested proved...
Coagulase negative Staphylococci (CoNS) are common inhabitants of human skin and mucous membranes. With the emergence these organisms as prominent pathogens in patients with ocular infections, investigation has intensified an effort to identify important virulence factors inform new approaches treatment prevention.To isolate CoNS from specimens; study possible factors; speciation coagulase staphylococci which were isolated complications; antibiotic susceptibility testing CoNS.The specimens...
Mycotic/fungal keratitis is a suppurative, generally ulcerative infection of the cornea. The filamentous fungi, Aspergillus spp. are second leading cause mycotic keratitis, particularly in India. produce range extracellular enzymes that used to break down complex molecules and for growth reproduction, also survival on/in host organism. current study was designed with an objective screen vitro enzyme activity Fusarium isolates from patients correlate same as putative virulence factor....
Graphium eumorphum is rarely associated with mycotic keratitis. We report the case of a 30-year-old female presented complaints redness and defective vision in left eye for one month. Gram staining 10% KOH wet mount corneal smears revealed fungal filaments. On potato dextrose agar, fast growing greyish white colonies turning grayish black on maturity was obtained. Lactophenol cotton blue (LPCB) confirmed isolate as eumorphum. The infection resolved combination natamycin, econazole itraconazole.
To isolate and identify the molds involved in mycotic keratitis; to corresponding species from soil samples; compare extracellular enzyme activity indices of isolated keratitis cases isolates.The specimens were collected target patients attending microbiology laboratory tertiary eye hospital Coimbatore, Tamilnadu state, India. The isolates subjected for identification based on growth solid media, direct microscopy lacto phenol cotton blue wet mount preparation. Extracellular enzymes such as...
Aspergillus keratitis are in the increasing trend and reported as second most common cause of mycotic developing countries. The present study was designed to isolate, identify spp. from keratits/corneal ulcer patients attending a tertiary care eye hospital, Coimbatore, South India assess minimum inhibitory concentrations (MICs) against ten clinically used first-line antifungal drugs. A total seventy-three strains isolated corneal scrapings were included assessed for period one year. All...
Methods The ocular samples viz., corneal swab, scraping, aqueous tap and vitreous were processed for culture the isolated Nocardia species further confirmed speciation by standard microbiological procedures. Antibiotic susceptibility analysis isolates of N. asteroides was performed agar disk diffusion method following guidelines Clinical Laboratory Standard Institute (CLSI, 2000).
To investigate the dematiaceous fungal profile of patients with ocular mycoses attending a tertiary eye care hospital in Coimbatore, India METHODS: The identification fungus based on their morphology, genotypes, and measurement minimum inhibitory concentrations (MICs) using microdilution method routinely used antifungal drugs were all compared.A total 148 fungi isolated during study period 27 months. Isolates confirmed as Curvularia spp. (n = 98), Exserohilum 32), Alternaria 14), Exophiala...
This study aims to investigate the ability of laccase producing fungal strains Cladosporium uredinicola GRDBF21 and Bipolaris maydis GRDBF23 isolated from decaying wood bark in decolouration detoxification tannery effluent.Fungal samples were by serial dilution technique followed single spore isolation method.The selected isolates investigated for their enzyme production.Their effect on physio-chemical properties effluent collected final drainage a leather-tanning factory Chrompet, Chennai,...
A research study was undertaken to find a fungus that could effectively trap and kill Meloidogyne spp., which are root-knot nematodes cause significant crop loss worldwide. Soil samples were collected processed appropriately for the isolation of nematode-trapping fungi. After primary screening, potential fungus, Arthrobotrys oligospora (Orbilia oligospora) PSGSS01 selected further investigation. Its growth tested under various conditions, including different media types, temperatures, pH...
The present study explored the ability of lignin-degrading enzyme-producing fungal isolates, Cladosporium uredinicola GRDBF21 (Accession No. KJ913698) and Bipolaris maydis GRDBF23 KJ913699) in biodegradation structurally complex CPS. Axenic cultures test isolates were acclimatised to CPS Czapek Dox broth (CDB) containing 50 mgL−1 followed by 100 subsequently with 200 as only carbon source. A comparative evaluation biomass production presence absence was made. evaluated Gas...