A5048365932- Petroleum Processing and Analysis
- Mass Spectrometry Techniques and Applications
- Hydrocarbon exploration and reservoir analysis
- Marine Toxins and Detection Methods
- Aquatic Ecosystems and Phytoplankton Dynamics
- Forensic Toxicology and Drug Analysis
- Marine and coastal ecosystems
- Cultural Heritage Materials Analysis
- Cancer Treatment and Pharmacology
- Tuberculosis Research and Epidemiology
- Cancer therapeutics and mechanisms
- Oil Spill Detection and Mitigation
- Geological and Tectonic Studies in Latin America
- Analytical Chemistry and Chromatography
- Hormonal and reproductive studies
- Toxic Organic Pollutants Impact
- Pharmacogenetics and Drug Metabolism
- Lanthanide and Transition Metal Complexes
- Veterinary Pharmacology and Anesthesia
- Bacterial Identification and Susceptibility Testing
- Water Treatment and Disinfection
- Global Energy and Sustainability Research
- Analytical chemistry methods development
- Plant-based Medicinal Research
- Mercury impact and mitigation studies
National Center for Environmental Health
2021-2024
Centers for Disease Control and Prevention
2019-2024
Florida State University
2015-2019
Battelle
2019
National High Magnetic Field Laboratory
2015-2017
Here, we present atmospheric pressure photoionization (APPI) Fourier transform ion cyclotron resonance (FTICR) mass analysis of a volcanic asphalt sample by acquiring data for 20 Da wide segments across 1000 range, stitched into single composite spectrum, and compare to broad-band spectrum the same sample. The segmented contained 170 000 peaks with magnitude greater than 6σ root-mean-square (rms) baseline noise, which 126 264 unique elemental compositions could be assigned. Approximately...
Coal tar and its distilled products (e.g., creosote) are commonly applied wood preservatives asphalt sealants that have been identified as significant sources of polycyclic aromatic hydrocarbons (PAHs) to the environment. Despite predictions coal is composed hundreds compounds, few studies ventured beyond measuring select PAHs with gas chromatography–mass spectrometry (GC-MS). Expanding target analyte list will improve our capacity gauge inputs impacts organic compounds released from into...
As levels of natural organic matter (NOM) in surface water rise, the minimization potentially harmful disinfection by-products (DBPs) becomes increasingly critical. Here, we introduce advantage that chromatographic prefractionation brings to investigating compositional changes NOM caused by chlorination. Fractionation reduces complexity, making it easier observe and attribute them specific components. Under conditions tested (0.1-0.4 g Cl C without further additives), differences between...
We report chemical characterization of natural oil seeps from the Gulf Mexico by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) and Gas Chromatography/Atmospheric Pressure Chemical Ionization Mass Spectrometry (GC/APCI-MS), to highlight how FT-ICR MS can also be employed as a means determine petroleum connectivity, in addition traditional GC/MS techniques. The source is Green Canyon (GC) 600 lease block Mexico. Within GC600, two seepage zones, Mega Plume Birthday...
Corrosion control at refineries remains a challenge because the mechanism of naphthenic acid (NAP) corrosion is still not fully understood. The rate NAP does correlate with acidity (as measured by total number); therefore, it has been suggested that subset in petroleum fractions may be more corrosive than others. Because primary product (iron naphthenates) thermally decompose to ketones temperatures (250–400 °C), fluids could potentially used implicate specific problematic acids tests. To...
To combat the ongoing opioid epidemic, our laboratory has developed and evaluated an approach to detect fentanyl analogs in urine plasma by screening LC–QTOF MS/MS spectra for ions that are diagnostic of core structure. data from a training set 142 were used select four product six neutral losses together provided most complete coverage (97.2%) compounds. Furthermore, using ion screen against 49 not resulted 95.9% those With this approach, lower reportable limits subset fentanyl-related...
ABSTRACT Natural toxins present an ongoing risk for human exposure that requires a rapid, accurate diagnosis proper response. In this study, qualitative liquid chromatography high resolution mass spectrometry (LC-HRMS) method was developed and validated the detection of large, diverse selection natural toxins. Data-dependent acquisition performed to identify compounds with in-house spectral library 129 hazardous originate from plants, animals, fungi. All were spiked into urine, extracted,...
Because the rate of naphthenic acid corrosion does not correlate with concentration acids, it has been proposed that a subset acids in petroleum fractions may be more corrosive than others. The primary products (iron naphthenates) decompose to form ketones at temperatures (250–400 °C), so characterization fluids could potentially used identify reactive generated iron naphthenate. Previous work model reported development method characterize such by isolation strong anion exchange separation...
Microcystins are toxic chemicals generated by certain freshwater cyanobacteria. These can accumulate to dangerous levels during harmful algal blooms. When exposed microcystins, humans at risk of hepatic injury, including liver failure. Here, we describe a method detect microcystins in human plasma using immunocapture followed protein phosphatase inhibition assay. At least 279 have been identified, and most these compounds share common amino acid, the Adda side chain. We targeted this chain...