A5090300248- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Urinary and Genital Oncology Studies
- MicroRNA in disease regulation
- Bladder and Urothelial Cancer Treatments
- Vascular Anomalies and Treatments
- Urological Disorders and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- RNA modifications and cancer
- Meningioma and schwannoma management
- Moyamoya disease diagnosis and treatment
- Endoplasmic Reticulum Stress and Disease
- Brain Metastases and Treatment
- Cardiovascular Disease and Adiposity
- Methemoglobinemia and Tumor Lysis Syndrome
- Heme Oxygenase-1 and Carbon Monoxide
- Peripheral Artery Disease Management
- Advanced MRI Techniques and Applications
- Nerve injury and regeneration
- Vascular Malformations and Hemangiomas
- Diabetic Foot Ulcer Assessment and Management
- Reconstructive Surgery and Microvascular Techniques
Beijing Tian Tan Hospital
2021-2025
Capital Medical University
2021-2025
National Clinical Research Center for Digestive Diseases
2023-2024
Sun Yat-sen University
2020-2024
Sun Yat-sen University Cancer Center
2020-2024
Kunming Medical University
2007-2023
Jiangsu Cancer Hospital
2021
Nanjing Medical University
2021
State Key Laboratory of Oncology in South China
2020
First Affiliated Hospital of Xinjiang Medical University
2017
Background The hemodynamics of brain arteriovenous malformations (AVMs) may have implications for hemorrhage. This study aimed to explore the ruptured AVMs by direct microcatheter intravascular pressure monitoring (MIPM) and indirect quantitative digital subtraction angiography (QDSA). Methods We recruited patients with at a tertiary neurosurgery center from October 2020 March 2023. In terms MIPM, we preoperatively super-selected predominant feeding artery main draining vein through measure...
Abstract Background The triglyceride glucose-body mass index (TyG-BMI index) has been suggested as a novel predictor of insulin resistance. However, its predictive value for slow coronary flow phenomenon (SCFP) in patients with ischemia and nonobstructive arteries (INOCA) remains unclear. Methods We consecutively recruited 1625 INOCA from February 2019 to 2023 divided them into two groups based on thrombolysis myocardial infarction (TIMI) frame counts (TFCs): the SCFP group ( n = 79) control...
Colon carcinoma is one of the most common cancers worldwide. Epidemiological studies have revealed that colon cancer third leading cause cancer‑related deaths, which due to increased incidence and mortality rates. However, treatment strategies for remain unsatisfactory patients, especially those with advanced or recurrent cancer. Dysregulated microRNAs (miRNAs) are considered influence tumor development metastasis. molecular mechanism through miRNAs affect progression not yet completely...
The optimal microsurgical timing in ruptured brain arteriovenous malformations (AVMs) is not well understood and surrounded by controversy. This study aimed to elucidate the impacts of resection on clinical outcomes.
Due to the high mortality and disability rate of intracranial hemorrhage, headache is not main focus research on cerebral arteriovenous malformation (AVM), so headaches in AVM still scarce, clinical understanding shallow. This study aims delineate risk factors associated with compare effectiveness various intervention treatments versus conservative treatment alleviating symptoms.
Patients with hepatitis B virus (HBV)-related cirrhosis (HBV-RC) and minimal hepatic encephalopathy (MHE) exhibit alterations in homotopic inter-hemispheric functional connectivity (FC) corpus callosum (CC) degeneration. However, the progression of dysconnectivity cirrhotic patients from no MHE (NMHE) to its association diseased-related cognitive impairment remain uncharacterized. We hypothesized that exists NMHE further deteriorates at stage, which is associated performance measured by...
Background: More and more elderly patients are being diagnosed with arteriovenous malformation (AVM) in this global aging society, while the treatment strategy remains controversial among these population. This study aimed to clarify long-term outcomes of AVMs after different management modalities. Methods: The authors retrospectively reviewed 71 (>60 years) two tertiary neurosurgery centers between 2011 2019. Patients were divided into four groups: conservation, microsurgery,...
Serum bilirubin plays an important role in antioxidant and anticancer processes. The inverse association between serum cancer risk have been widely reported multiple cancers. aim of this retrospective study was to investigate the prognostic impact colorectal patients undergoing surgical resection.The value including total bilirubin, direct indirect were tested at pre-operatively 330 patients. optimal cut-off values for these three biomarkers determined by X-tile program. relationship...
OBJECTIVE This study aimed to explore whether intervention can benefit Spetzler-Martin (SM) grade IV–V arteriovenous malformations (AVMs). METHODS Eighty-two patients with SM AVMs were retrospectively reviewed from 2015 2018. Patients divided into two groups: those who received conservative management (22 cases [26.8%]) and (60 [73.2%], including 21 of microsurgery, 19 embolization, 20 hybrid surgery). Neurofunctional outcomes assessed the modified Rankin Scale (mRS). The primary outcome was...
Background To compare the long-term outcomes of stereotactic radiosurgery (SRS) with or without prior embolization in brain arteriovenous malformations (AVMs) (volume ≤10 mL) for which SRS is indicated. Methods Patients were recruited from a nationwide multicenter prospective collaboration registry (the MATCH study) between August 2011 and 2021, categorized into combined (E+SRS) alone cohorts. We performed propensity score-matched survival analysis to risk non-fatal hemorrhagic stroke death...
This study aimed to investigate the natural history of re-rupture in ruptured brain arteriovenous malformations (AVMs) and provide comprehensive insights into its associated factors prevention.
Rupture is the most life-threatening manifestation of cerebral AVMs. This study aimed to explore hemodynamic mechanism AVM rupture. We introduced a new quantitative DSA parameter that can reflect degree intranidal blood stasis, called lesion-filling index.
Background: Although postoperative adjuvant transarterial chemoembolization (PA-TACE) improves survival outcomes in a subset of patients with resected hepatocellular carcinoma (HCC), the lack reliable biomarkers for patient selection remains significant challenge. The present study aimed to evaluate whether computed tomography (CT) imaging can provide more value predicting benefits from PA-TACE and establish new scheme guiding benefits. Methods: In this retrospective study, HCC who had...
Background: This study aimed to compare the risk and benefit profile of microsurgery (MS) stereotactic radiosurgery (SRS) as first-line treatment for unruptured ruptured arteriovenous malformations (AVMs). Materials Methods: We included AVMs underwent MS or SRS from a nationwide prospective multicenter registry in *BLINDED*. used propensity score-matched methods balance baseline characteristics between groups. The primary outcomes were long-term hemorrhagic stroke death, secondary...
Abstract Aims To compare the efficacy and deficiency of conservative management (CM), microsurgery (MS) only, with preoperative embolization (E + MS) for unruptured arteriovenous malformations (AVMs). Methods We prospectively included AVMs undergoing CM, MS, E MS from our institution between August 2011 2021. The primary outcomes were long‐term neurofunctional hemorrhagic stroke death. In addition to comparisons among was divided into single‐staged hybrid multi‐staged further analysis....
Objectives This study aimed to assess the effectiveness of two-trait predictor venous invasion (TTPVI) on contrast-enhanced computed tomography (CECT) for preoperative prediction clinical outcomes in patients with early-stage hepatocellular carcinoma (HCC) after hepatectomy. Methods retrospective included 280 surgically resected HCC who underwent CECT between 2012 and 2013. CT imaging features were assessed, univariate multivariate Cox regression analyses used evaluate associated...