A5101589724- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer, Hypoxia, and Metabolism
- Bioinformatics and Genomic Networks
- Skin and Cellular Biology Research
- Lung Cancer Research Studies
- Cancer Mechanisms and Therapy
- Dermatology and Skin Diseases
- Skin Protection and Aging
- Diphtheria, Corynebacterium, and Tetanus
- Healthcare Technology and Patient Monitoring
- Petri Nets in System Modeling
- Advanced Graph Neural Networks
- Context-Aware Activity Recognition Systems
- RNA modifications and cancer
Peking University Cancer Hospital
2017-2022
Peking University
2017-2022
Army Medical University
2012-2019
Centers for Disease Control and Prevention
2012
// Chao Liu 1, 2, * , En-Dong Yun-Xiao Meng 3, Xiao-Ming Dong 4 Ya-Lan Bi 3 Huan-Wen Wu Yan-Chao Jin 2 Ke Zhao Jian-Jie Li 5 Miao Yu Yi-Qun Zhan Hui Chen Chang-Hui Ge Yang and Chang-Yan 1 An Medical University, Hefei, 230032, China State Key Laboratory of Proteomics, Beijing Proteome Research Center, Institute Radiation Medicine, Beijing, 100850, Department Pathology, Peking Union College Hospital, Chinese Academy Sciences College, Tsinghua 100730, Tianjin School Chemical Engineering...
We aimed to identify a panel of circulating plasma microRNAs that can predict EGFR mutation status and monitor epidermal growth factor receptor-tyrosine kinase inhibitor treatment in patients with non-small cell lung cancer. Microarrays were performed for the preliminary screening dysregulated 9 mutation-positive versus healthy controls. MiR-107 was upregulated miR-195 downregulated exon 19 deletion wild-type group. The areas under receiver operating characteristic curves miR-107, miR-195,...
Background: The abnormal expression of miRNAs facilitates tumorigenesis and development. miR-181a-2-3p is up-regulated in various cancers, yet its mechanism gastric cancer (GC) remains elusive. Objective: To understand stimulating GC cell progression via targeting Myosin Light Chain Kinase (MYLK) expression. Methods: Downstream genes miRNA interest were predicted TargetScan miRTarBase. qRT-PCR western blot applied to assess MYLK cells normal cells. Dual-luciferase RIP assays completed...
Gastric cancer (GC) accounts for a main cause of cancer-related deaths. This study sought molecular mechanism miR-490-5p/DTL axis in affecting GC progression, thus bringing new hope treatment GC. Expression data differentially expressed miRNAs and mRNAs tissue from TCGA database were analyzed. MiR-490-5p DTL mRNA expression levels evaluated with qRT-PCR. Cell viability was confirmed CCK-8 method. cycle distribution apoptosis analyzed flow cytometry. migratory invasive potential proved...
To improve the rescue process, enhance efficiency of and support decision health service in action, process triage disaster action performed by mobile medical unit is analyzed. Firstly, procedure analyzed qualitatively Stochastic Petri Net introduced briefly. Then based on qualitative analysis, modeled using stochastic net. The net model executed with aid computer its isomorphic Markov chain relative matrix obtained. average delay can be measured through maneuver or actual operation made as...
The mechanism of hypoxia is an important research topic biomedicine. current studies usually only focus on particular aspects hypoxia-specific issues based methods and technologies traditional biomedicine, seldom investigate from a systematic perspective. In this paper, the treated network point view. structural composition response analyzed perspective complex networks. overall HIF-1 signaling pathway established, its properties, such as topology, centrality, cohesive subgroups are theory...