- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
- Preterm Birth and Chorioamnionitis
- Pregnancy-related medical research
- Neonatal Respiratory Health Research
- Pregnancy and Medication Impact
- Assisted Reproductive Technology and Twin Pregnancy
- Birth, Development, and Health
- Infant Development and Preterm Care
- Trauma and Emergency Care Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Cardiovascular Issues in Pregnancy
- Gestational Diabetes Research and Management
- Emergency and Acute Care Studies
- Clinical practice guidelines implementation
- Electrolyte and hormonal disorders
- Global Maternal and Child Health
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Pelvic floor disorders treatments
- Pharmacological Effects and Toxicity Studies
- Bariatric Surgery and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Agriculture Sustainability and Environmental Impact
- Grief, Bereavement, and Mental Health
Maastricht University Medical Centre
2016-2025
Maastricht University
2016-2025
University Medical Center
2012-2024
Leiden University Medical Center
2001-2019
Isala
2018-2019
University Medical Center Groningen
2010-2019
Radboud University Nijmegen
2007-2019
Radboud University Medical Center
2007-2019
University of Groningen
2015-2019
Emma Kinderziekenhuis
2015-2019
To estimate the performance of combining cervical length measurement with fetal fibronectin testing in predicting delivery women symptoms preterm labor.We conducted a prospective nationwide cohort study all 10 perinatal centers The Netherlands. Women labor between 24 and 34 weeks gestation intact membranes were included. In women, qualitative (0.050-microgram/mL cutoff) performed. Logistic regression was used to predict spontaneous within 7 days after testing. A risk less than 5%,...
RETERM BIRTH IS THE MOST COMmon cause of neonatal morbidity and mortality worldwide.Almost 75% perinatal deaths occur in infants born before 37 weeks' gestation. 1Consequently, pre-term birth is associated with a large burden disease, high costs for medical care, special education, institutionalized care disabled infants. 2 In threatened preterm labor 34 weeks, delay delivery 48 hours allows antenatal corticosteroid treatment to improve fetal maturity transfer the pregnant woman center...
A large number of studies have shown an association between inherited thrombophilia and recurrent miscarriage. It has been hypothesized that anticoagulant therapy might reduce the miscarriages stillbirth in these women. In absence randomized controlled trials evaluating efficacy women with miscarriage, a trial adequate power addresses this question is needed. The objective ALIFE2 study therefore to evaluate low-molecular-weight heparin (LMWH) live birth as primary outcome.Randomized LMWH...
To develop a nationwide, evidence-based framework to support prenatal counseling in extreme prematurity, focusing on organization, decision-making, content, and style aspects.A nationwide multicenter RAND-modified Delphi method study was performed between November 2016 December 2017 the Netherlands. Firstly, recommendations were extracted from literature previous studies. Secondly, an expert panel (n = 21) with experienced parents, obstetricians, neonatologists rated importance for inclusion...
Double-layer compared to single-layer closure of the uterus after a caesarean section (CS) leads thicker myometrial layer at site CS scar, also called residual myometrium thickness (RMT). It possibly decreases development niche, which is an interruption uterine scar. Thin RMT and niche are associated with gynaecological symptoms, obstetric complications in subsequent pregnancy delivery subfertility.
long-term data about uterine cesarean closure technique.Tweetable statement: Double-layer after a first section showed no superiority over single-layer in 3-years follow-up outcomes. AJOG at Glance A. Why was this study conducted?The aimed to address the lack of consensus on optimal technique, given suggested association between technique and niche development.Insufficient evidence existed for (long-term) outcomes, including obstetric, gynecological fertility aspects, concerning...
Preterm prelabour rupture of the membranes (PPROM) is an important clinical problem and a dilemma for gynaecologist. On one hand, awaiting spontaneous labour increases probability infectious disease both mother child, whereas on other hand induction leads to preterm birth with increase in neonatal morbidity (e.g., respiratory distress syndrome (RDS)) possible rise number instrumental deliveries. We aim determine effectiveness cost-effectiveness immediate delivery after PPROM near term...
Decisions at the limits of viability about initiating care are challenging. We aimed to investigate physicians' preferences on treatment decisions, against background 2010 Dutch guideline offering active from 24+0/7 weeks gestational age (GA). Obstetricians' and neonatologists' opinions were compared. An online survey was conducted amongst all perinatal professionals (n = 205) 10 level III centers. Response rate 60 % 122). Comfort mostly recommended below intensive over 26+0/7 weeks. The...
Adequate calcium intake during pregnancy is of major importance for the health both mother and fetus. Up to date, evidence on prevalence inadequate among pregnant women sparse Western countries, it unknown what extent dietary adequately balanced by supplement use. The objective this study was estimate from diet use early in Netherlands. As part Expect cohort study, 2477 (8–16 weeks gestation) completed an online questionnaire including questions baseline characteristics, containing...