- Maternal and Perinatal Health Interventions
- Reproductive Health and Contraception
- Maternal and fetal healthcare
- Pregnancy-related medical research
- Pregnancy and Medication Impact
- Electrolyte and hormonal disorders
- Pregnancy and preeclampsia studies
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal Mental Health During Pregnancy and Postpartum
- Ectopic Pregnancy Diagnosis and Management
- Preterm Birth and Chorioamnionitis
- Sexual function and dysfunction studies
- Pharmacological Effects and Toxicity Studies
- Migration, Health and Trauma
- Urticaria and Related Conditions
- Sexuality, Behavior, and Technology
- RNA modifications and cancer
- Grief, Bereavement, and Mental Health
- Cancer-related molecular mechanisms research
- Clinical practice guidelines implementation
- Homicide, Infanticide, and Child Abuse
- Healthcare Systems and Practices
- Global Health Workforce Issues
- Adolescent Sexual and Reproductive Health
- Reproductive Health and Technologies
Flevoziekenhuis
2009-2022
Atria
2022
De Kinderkliniek
2008-2021
Amsterdam UMC Location University of Amsterdam
1984-2018
University of British Columbia
2018
St Thomas' Hospital
2018
King's College London
2018
University of Toronto
2018
The University of Adelaide
2018
South Australian Health and Medical Research Institute
2018
Preterm birth is the leading cause of neonatal morbidity and mortality. The recurrence rate spontaneous preterm high, additional preventive measures are required. Our objective was to assess effectiveness low-dose aspirin compared placebo in prevention women with a previous birth.
The HELLP syndrome is a pregnancy-associated disease inducing hemolysis, elevated liver enzymes, and low platelets in the mother. Although symptoms occur third trimester mother, origin of can be found first fetal placenta. A locus for present on chromosome 12q23 near PAH. Here, by multipoint nonparametric linkage, pedigree structure allele sharing, haplotype association analysis affected sisters cousins, we demonstrate that an intergenic region 12q23.2 between PMCH IGF1. We identified novel...
Analysis of factors influencing surgical intervention rate after home medical termination pregnancy (TOP) by women in countries without access to safe services using the telemedical service 'Women on Web'.Cohort study.Women with an unwanted less than nine weeks pregnant who used telemedicine Women Web between February 2007 and September 2008 provided follow-up information.Women TOP a known follow up.Information from online consultation, form emails was analyze outcome TOP.Ongoing pregnancy,...
Objective To develop and internally validate a model that predicts the outcome of an intended vaginal birth after caesarean ( VBAC ) for Western European population can be used to personalise counselling deliveries at term. Design Registration‐based retrospective cohort study. Setting Five university teaching hospitals, seven non‐university five non‐teaching hospitals in Netherlands. Population A 515 women with history one section viable singleton pregnancy, without contraindication , who...
Objective To externally validate two models from the USA (entry‐to‐care [ ETC ] and close‐to‐delivery CTD ]) that predict successful intended vaginal birth after caesarean ( VBAC ) for Dutch population. Design A nationwide registration‐based cohort study. Setting Seventeen hospitals in Netherlands. Population Seven hundred sixty‐three pregnant women, each with one previous section a viable singleton cephalic pregnancy without contraindication an . Methods The model comprises variables...
To assess the cost-effectiveness of a cervical pessary to prevent preterm delivery in women with multiple pregnancy.The study design comprised an economic analysis data from randomized clinical trial evaluating pessaries (ProTWIN). Women pregnancy were included and evaluation was performed societal perspective. Costs estimated between time randomization 6 weeks postpartum. The prespecified subgroup length (CL) < 25(th) centile (< 38 mm) analyzed separately. primary endpoint poor perinatal...
To evaluate the efficacy and safety of home administration buccal misoprostol after mifepristone for medical abortion up to 70 days' gestation in a general practice Curaçao, where induced is severely restricted by law.In prospective study 330 women received 200 mg were instructed take four tablets (800 μg) via route 24-36 h later, at home. One week follow-up took place.The outcome could be evaluated 307 women. The mifepristone-buccal procedure was 97.7% (300/307). In seven vacuum aspirations...
To assess the costs of labour induction with oral misoprostol versus Foley catheter.Economic evaluation alongside a randomised controlled trial.Obstetric departments six tertiary and 23 secondary care hospitals in Netherlands.Women viable term singleton pregnancy cephalic presentation, intact membranes, an unfavourable cervix (Bishop score <6) without previous caesarean section, were for (n = 924) or catheter 921).We performed economic analysis from hospital perspective. We estimated direct...
Abstract Introduction Hyperemesis gravidarum (HG) complicates 1% of pregnancies and has a major impact on maternal quality life well‐being. We know very little about HG’s long‐term after an affected pregnancy, including recurrence rates in future pregnancies, which is essential information for women considering subsequent pregnancies. In this study, we aimed to prospectively measure the rate HG number postponed terminated due HG. also evaluate if there were predictive factors that could...
Objective To determine the prevalence of depression, anxiety, and posttraumatic stress disorder (PTSD) years after hyperemesis gravidarum (HG) its association with HG severity.Material methods This prospective cohort study consisted a follow-up 215 women admitted for HG, who were eligible to participate in randomized controlled trial either declined or agreed be between 2013 2016 19 hospitals Netherlands. Participants completed Hospital Anxiety Depression Scale (HADS) six weeks postpartum...
In Brief OBJECTIVE: To estimate the effectiveness of nifedipine as a uterine relaxant during external cephalic version to correct breech presentation. METHODS: this randomized, double-blind, placebo-controlled trial, women with singleton fetus in presentation and gestational age 36 weeks or more were eligible for enrollment. Participating received two doses either 10 mg placebo, 30 15 minutes before attempt. The primary outcome was cephalic-presenting immediately after procedure. Secondary...
Objective: To evaluate whether progression to a high-risk situation is predictable in women with gestational hypertension (GH) or mild pre-eclampsia (PE) at term. Methods: Women singleton pregnancy, fetus cephalic position, between 36 and 41 weeks of gestation, complicated by GH PE that were managed expectantly, selected from the HYPITAT trial. We evaluated predictability situation. Logistic regression was used determine predictive value clinical characteristics laboratory findings generate...
Abstract Objectives Previous studies on singleton pregnancies have indicated that progestogens may reduce the rate of cervical shortening during pregnancy. The aim this study was to investigate whether treatment with 17‐alpha hydroxyprogesterone caproate (17‐OHPC) has an effect in twin pregnancies. Methods This a secondary analysis patients who had participated multicenter randomized clinical trial effectiveness 17‐OHPC preventing preterm birth multiple (the AMPHIA‐trial). We included all...