A5013610992- Neonatal Respiratory Health Research
- Neuroscience of respiration and sleep
- Congenital Diaphragmatic Hernia Studies
- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Cardiac Arrest and Resuscitation
- Congenital Heart Disease Studies
- Respiratory Support and Mechanisms
- Cardiovascular Conditions and Treatments
- Ethics and Legal Issues in Pediatric Healthcare
- Airway Management and Intubation Techniques
- Infant Nutrition and Health
- Mechanical Circulatory Support Devices
- Childhood Cancer Survivors' Quality of Life
- Ultrasound in Clinical Applications
- Non-Invasive Vital Sign Monitoring
- Assisted Reproductive Technology and Twin Pregnancy
- Hemodynamic Monitoring and Therapy
- Prenatal Screening and Diagnostics
- Pharmacological Effects and Toxicity Studies
- Trauma and Emergency Care Studies
- Neonatal skin health care
- Family and Patient Care in Intensive Care Units
- Neonatal Health and Biochemistry
- Preterm Birth and Chorioamnionitis
Sharp Mary Birch Hospital for Women & Newborns
2016-2025
University of California, San Diego
2010-2024
University of Utah
2020-2023
Providence St. Vincent Medical Center
2023
GW Medical Faculty Associates
2023
University of Alberta
2023
Cleveland Clinic
2023
Sharp Grossmont Hospital
2023
Loma Linda University Children's Hospital
2023
UC San Diego Health System
2023
<h3>Importance</h3> Umbilical cord milking as an alternative to delayed umbilical clamping may provide equivalent benefits preterm infants, but without delaying resuscitation. <h3>Objective</h3> To determine whether the rates of death or severe intraventricular hemorrhage differ among infants receiving placental transfusion with vs clamping. <h3>Design, Setting, and Participants</h3> Noninferiority randomized clinical trial (born at 23-31 weeks' gestation) from 9 university private medical...
Delayed cord clamping (DCC) is recommended for premature infants to improve blood volume. Most preterm are born by cesarean delivery (CD), and placental transfusion may be less effective than in vaginal (VD). We sought determine whether <32 weeks CD who undergo umbilical milking (UCM) have higher measures of systemic flow DCC.This was a 2-center trial. Infants delivered were randomly assigned UCM or DCC. VD also separately. (4 strippings) DCC (45-60 seconds) performed. Continuous hemodynamic...
<h3>Importance</h3> Preterm infants must establish regular respirations at delivery. Sustained inflations may lung volume faster than short inflations. <h3>Objective</h3> To determine whether a ventilation strategy including sustained inflations, compared with standard intermittent positive pressure ventilation, reduces bronchopulmonary dysplasia (BPD) or death 36 weeks' postmenstrual age without harm in extremely preterm infants. <h3>Design, Setting, and Participants</h3> Unmasked,...
The first case of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) was reported in November2019. rapid progression to a global pandemic COVID-19 has had profound medical, social, and economic consequences. Pregnant women newborns represent vulnerable population. However, the precise impact this virus on fetus neonate remains uncertain. Appropriate protection health care workers newly born infants during after delivery mother is...
Exogenous surfactants to treat respiratory distress syndrome (RDS) are approved for tracheal instillation only; this requires intubation, often followed by positive pressure ventilation promote distribution. Aerosol delivery offers a safer alternative, but clinical studies have had mixed results. We hypothesized that efficient aerosolization of surfactant with low viscosity, early in the course RDS, could reduce need intubation and liquid surfactant.A prospective, multicenter, randomized,...
<b>Objective</b> This study aims to compare the effects of early and late (routine) initiation caffeine in nonintubated preterm neonates. <b>Study Design</b> A total 21 neonates < 29 weeks gestational age were randomized receive intravenous citrate (20 mg/kg) or placebo either before 2 hours (early) at 12 (routine). was an observational trial determine power needed reduce need for endotracheal intubation by age. Other outcomes included comparisons cerebral oxygenation, systemic pulmonary...
Background Umbilical cord milking (UCM) improves blood pressure and urine output, decreases the need for transfusions in comparison to immediate clamping (ICC). The effect of UCM first few minutes life impact on neonatal resuscitation has not been described. Methods Women admitted a tertiary care center delivering before 32 weeks gestation were randomized receive or ICC. A blinded analysis physiologic data collected newborns delivery room was performed using acquisition system. Heart rate...
OBJECTIVES To determine whether rate of severe intraventricular hemorrhage (IVH) or death among preterm infants receiving placental transfusion with UCM is noninferior to delayed cord clamping (DCC). METHODS Noninferiority randomized controlled trial comparing versus DCC in born 28 32 weeks recruited between June 2017 through September 2022 from 19 university and private medical centers 4 countries. The primary outcome was Grade III/IV IVH evaluated at a 1% noninferiority margin. RESULTS...
<b>Background</b> Electrical cardiometry (EC) is a continuous noninvasive method for measuring cardiac output (CO), but there are limited data on premature infants. We evaluated the utility of EC monitoring by comparing results obtained using to measurements CO and systemic blood flow echocardiography (ECHO). <b>Methods</b> In this prospective observational study, 40 preterm neonates underwent 108-paired ECHO measurements. <b>Results</b> There were correlations between EC-CO left ventricular...