Richard A. Polin
A5088251860- Neonatal Respiratory Health Research
- Neonatal and Maternal Infections
- Infant Development and Preterm Care
- Congenital Diaphragmatic Hernia Studies
- Neonatal and fetal brain pathology
- Streptococcal Infections and Treatments
- Neonatal Health and Biochemistry
- Neuroscience of respiration and sleep
- Respiratory Support and Mechanisms
- Infant Nutrition and Health
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Congenital Heart Disease Studies
- Metabolism and Genetic Disorders
- Child and Adolescent Health
- Birth, Development, and Health
- Bacterial Infections and Vaccines
- Cell Adhesion Molecules Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Methemoglobinemia and Tumor Lysis Syndrome
- Preterm Birth and Chorioamnionitis
- Immune Response and Inflammation
- Anesthesia and Neurotoxicity Research
- Cardiovascular Conditions and Treatments
- Clinical Nutrition and Gastroenterology
Columbia University
2015-2025
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2021-2025
Research Network (United States)
2021-2025
Health and Human Development (2HD) Research Network
2023-2025
Columbia University Irving Medical Center
2013-2024
Clinical Trial Investigators
2024
Children's Hospital of Philadelphia
1990-2023
St. Christopher's Hospital for Children
1979-2023
Rainbow Babies & Children's Hospital
1978-2023
RELX Group (Netherlands)
2016-2023
This Policy Statement was reaffirmed December 2021. Provision of risk-appropriate care for newborn infants and mothers first proposed in 1976. updated policy statement provides a review data supporting evidence tiered provision reaffirms the need uniform, nationally applicable definitions consistent standards service public health to improve neonatal outcomes. Facilities that provide hospital should be classified on basis functional capabilities, these facilities organized within...
Maternal use of certain drugs during pregnancy can result in transient neonatal signs consistent with withdrawal or acute toxicity cause sustained a lasting drug effect. In addition, hospitalized infants who are treated opioids benzodiazepines to provide analgesia sedation may be at risk for manifesting withdrawal. This statement updates information about the clinical presentation exposed intrauterine and therapeutic options treatment is expanded include evidence-based approaches management...
Persistent pulmonary hypertension of the newborn causes systemic arterial hypoxemia because increased vascular resistance and right-to-left shunting deoxygenated blood. Inhaled nitric oxide decreases in newborns. We studied whether inhaled severe infants with persistent hypertension.
With improved obstetrical management and evidence-based use of intrapartum antimicrobial therapy, early-onset neonatal sepsis is becoming less frequent. However, remains one the most common causes morbidity mortality in preterm population. The identification neonates at risk for frequently based on a constellation perinatal factors that are neither sensitive nor specific. Furthermore, diagnostic tests have poor positive predictive accuracy. As result, clinicians often treat well-appearing...
In Brief January 2015, the Eunice Kennedy Shriver National Institute of Child Health and Human Development invited an expert panel to a workshop address numerous knowledge gaps provide evidence-based guidelines for diagnosis management pregnant women with what had been commonly called chorioamnionitis neonates born these women. The noted that term has used label heterogeneous array conditions characterized by infection inflammation or both consequent great variation in clinical practice...
Despite improvement during recent decades, extremely preterm infants continue to contribute disproportionately neonatal mortality and childhood morbidity. To review survival, in-hospital morbidities, care practices, neurodevelopmental functional outcomes at 22-26 months' corrected age for infants. Prospective registry born 19 US academic centers that are part of the Eunice Kennedy Shriver National Institute Child Health Human Development Neonatal Research Network. The study included 10 877...
Respiratory failure secondary to surfactant deficiency is a major cause of morbidity and mortality in preterm infants. Surfactant therapy substantially reduces respiratory for this population. Secondary also contributes acute late-preterm term neonates with meconium aspiration syndrome, pneumonia/sepsis, perhaps pulmonary hemorrhage; replacement may be beneficial these This statement summarizes the evidence regarding indications, administration, formulations, outcomes surfactant-replacement...
OBJECTIVE. The goal of this study was to evaluate the role factors that may determine efficacy treatment with delayed head cooling and mild systemic hypothermia for neonatal encephalopathy. METHODS. A total 218 term infants moderate severe encephalopathy plus abnormal amplitude-integrated electroencephalographic recordings, assigned randomly 72 hours, starting within 6 hours after birth (with rectal temperature maintained at 34.5 ± 0.5°C), or conventional care, were studied. Death disability...
Importance Maternal milk feeding of extremely preterm infants during the birth hospitalization has been associated with better neurodevelopmental outcomes compared formula. For receiving no or minimal maternal milk, it is unknown whether donor human conveys similar advantages vs Objective To determine if nutrient-fortified, pasteurized improves at 22 to 26 months’ corrected age infant formula among who received milk. Design, Setting, and Participants Double-blind, randomized clinical trial...
This Clinical Report was retired March 2022. Herpes simplex virus (HSV) infection of the neonate is uncommon, but genital herpes infections in adults are very common. Thus, although treating an infant with neonatal a relatively rare occurrence, managing infants potentially exposed to HSV at time delivery occurs more frequently. The risk transmitting during determined part by mother’s previous immunity HSV. Women primary who shedding 10 30 times likely transmit their newborn than women...
Nitric oxide, an important signaling molecule with multiple regulatory effects throughout the body, is tool for treatment of full-term and late-preterm infants persistent pulmonary hypertension newborn hypoxemic respiratory failure. Several randomized controlled trials have evaluated its role in management preterm ≤ 34 weeks' gestational age varying results. The purpose this clinical report to summarize existing evidence use inhaled nitric oxide provide guidance regarding population.