Benjamin Carper
A5067763905- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Neonatal Respiratory Health Research
- Gestational Diabetes Research and Management
- Neuroscience of respiration and sleep
- Cardiovascular Issues in Pregnancy
- Urinary Bladder and Prostate Research
- Urinary Tract Infections Management
- Pregnancy and preeclampsia studies
- Diverticular Disease and Complications
- Stress Responses and Cortisol
- Neuroendocrine regulation and behavior
- Traumatic Brain Injury and Neurovascular Disturbances
- Congenital Heart Disease Studies
- Obstructive Sleep Apnea Research
- Traumatic Brain Injury Research
- Infant Development and Preterm Care
- Birth, Development, and Health
- Pressure Ulcer Prevention and Management
- Hormonal Regulation and Hypertension
- Vascular Anomalies and Treatments
- Pelvic and Acetabular Injuries
- Maternal Mental Health During Pregnancy and Postpartum
- Neurotransmitter Receptor Influence on Behavior
- Respiratory Support and Mechanisms
RTI International
2016-2025
National Heart Lung and Blood Institute
2024-2025
Health and Human Development (2HD) Research Network
2025
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2020-2024
Mayo Clinic in Arizona
2024
Johns Hopkins University
2024
Massachusetts General Hospital
2024
Island Institute
2020-2021
University of Pennsylvania Health System
2020-2021
University of Alabama at Birmingham
2021
Hereditary hemorrhagic telangiectasia (HHT) is characterized by extensive telangiectasias and arteriovenous malformations. The primary clinical manifestation epistaxis that results in iron-deficiency anemia reduced health-related quality of life.
Hospitalization of moderately preterm infants may be prolonged while waiting for apnea prematurity to resolve after discontinuing caffeine. To evaluate whether extending caffeine treatment reduces the duration hospitalization. From February 2019 December 2022, this randomized clinical trial in 29 US hospitals enrolled born at 33 weeks' gestation who 35 postmenstrual age were receiving with plans discontinue it plus full feeds (≥120 mL/kg/d). Follow-up was completed on March 20, 2023. Infants...
<h3>Importance</h3> Mixed urinary incontinence, including both stress and urgency has adverse effects on a woman's quality of life. Studies evaluating treatments to simultaneously improve components are lacking. <h3>Objective</h3> To determine whether combining behavioral pelvic floor muscle therapy with midurethral sling is more effective than alone for improving mixed incontinence symptoms. <h3>Design, Setting, Participants</h3> Randomized clinical trial involving women 21 years or older...
Although leisure-time physical activity (PA) contributes to overall health, including pregnancy patterns across have not been related birth outcomes. We hypothesized that women with sustained low PA would excess risk of adverse outcomes, and changing (high high) may also be outcomes.Nulliparous (n = 10,038) were enrolled at 8 centers early in (mean gestational age weeks [SD] 12.05 [1.51]. Frequency, duration, intensity (metabolic equivalents) up three leisure activities reported the first,...
To determine whether percutaneous tibial nerve stimulation (PTNS) is superior to sham for the treatment of fecal incontinence (FI) in women refractory first-line treatments. Women aged 18 years or older with ≥3 months moderate-to-severe FI that persisted after a 4-week run-in phase were randomized 2:1 (PTNS:sham stimulation) 12 weekly 30-minute sessions this multicenter, single-masked, controlled superiority trial. The primary outcome was change from baseline severity measured by St. Mark...
Influenza A viruses continue to pose a threat human health; thus, various vaccines and prophylaxis be developed. Testing of these products requires animal models including mice, guinea pigs, ferrets. However, because ferrets are naturally susceptible infection with influenza the disease state resembles that influenza, animals have been widely used as model study virus pathogenesis. In this report, statistical analysis was performed evaluate data involving 269 infected seasonal swine highly...
This study aimed to determine the effect of a run-in period on fecal incontinence (FI) symptom severity. conducted planned secondary analysis evaluating 12-week treatment with percutaneous tibial nerve stimulation versus sham in reducing FI severity women. All participants completed 4-week designed exclude from randomization women whose symptoms reduced below eligibility threshold after receiving education and completing bowel diaries. Change St Mark's (Vaizey) score weekly episodes during...
Importance Mixed urinary incontinence, which includes both stress and urgency adversely affects quality of life can be difficult to manage. Studies comparing procedural-based treatments for mixed incontinence are lacking. Objective To determine whether intradetrusor onabotulinumtoxinA is more effective than midurethral sling the treatment in females. Design, Setting, Participants Randomized, superiority trial involving females (aged ≥21 years) with moderate severe bother from who had...
Military personnel and athletes exposed to traumatic brain injury may develop chronic encephalopathy (CTE). Brain pathology in CTE includes intracellular accumulation of abnormally phosphorylated tau proteins (p-tau), the main constituent neurofibrillary tangles (NFTs). Recently, we found that cholinergic basal forebrain (CBF) neurons within nucleus basalis Meynert (nbM), which provide major innervation cortex, display an increased number NFTs across pathological stages CTE. However,...
Traumatic brain injury (TBI) is a serious public health concern which strikes someone every 15 seconds on average in the US. Even mild TBI, comprise as many 75% of all TBI cases, carries long term consequences. The effects age and sex outcome from not fully understood, but due to increased risk for neurodegenerative diseases after it important understand how these factors influence TBI. This study examined neurobehavioral neuropathological days following repetitive traumatic (r-mTBI) mice...