A5100322559- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Blood Pressure and Hypertension Studies
- Aortic Disease and Treatment Approaches
- Retinal Diseases and Treatments
- Cardiovascular Health and Risk Factors
- Cardiac Imaging and Diagnostics
- Retinal Imaging and Analysis
- Coronary Interventions and Diagnostics
- Cardiac tumors and thrombi
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Ischemia and Reperfusion
- Infective Endocarditis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Nutritional Studies and Diet
- Transplantation: Methods and Outcomes
- Adipose Tissue and Metabolism
- Lipoproteins and Cardiovascular Health
- Ocular Diseases and Behçet’s Syndrome
- Heart Rate Variability and Autonomic Control
- Cardiac Health and Mental Health
- Liver Disease Diagnosis and Treatment
Capital Medical University
2016-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2009-2025
Beijing Chao-Yang Hospital
2025
First Affiliated Hospital of Wannan Medical College
2024
Betta Pharmaceuticals (China)
2023-2024
First Affiliated Hospital of Xi'an Jiaotong University
2020-2024
Tongji University
2021-2024
Tongji Hospital
2024
Shandong First Medical University
2023
Shandong Tumor Hospital
2023
Abstract Background Triglyceride glucose (TyG) index is a new marker associated with atherosclerosis. This study aimed to assess the association between TyG and severity of coronary artery disease (CAD) in patients heart (CHD) further explore CAD different metabolic states. Methods multi-centre retrospective included 731 CHD January 1, 2014 September 30, 2020 China. All were stratified into groups based on tertiles (T1: 5.48 ≤ 7.17; T2: 7.18 7.76; T3: 7.77 10.82). The number diseased vessels...
Although remote ischemic stimuli have been shown to elicit cardioprotection against ischemia/reperfusion injury, there is little known about the effects of nonischemic stimuli. We previously described a cardioprotective effect surgical trauma (abdominal incision) called preconditioning (RPCT). In present study, we elucidate mechanisms underlying this phenomenon.We used murine model myocardial infarction evaluate and either abdominal incision, or application topical capsaicin,...
Hemodynamic data, including simultaneously measured left ventricular and aortic pressures, were obtained from 20 patients with isolated valvular stenosis at rest during supine leg exercise. Changes in end-diastolic pressure exercise not significantly related to the severity of but correlated age; abnormal pressures older than those whom this variable remained normal. Exercise resulted significant increases both mean rate systolic blood flow gradient across valve. Analysis demonstrated...
Recent guidelines recommend a systolic blood pressure (BP) goal of less than 150 mm Hg or even 130 for adults aged 60 years older. However, harms from intensive BP treatments occur immediately (eg, syncope, fall), and benefits cardiovascular event reduction emerge over time. Therefore, with low chance benefit need to be clearer, particularly those limited life expectancy.
Since the outbreak of Coronavirus Disease 2019 (COVID-19) in December 2019, many studies have reported presence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) conjunctival sac patients infected with this virus, several displaying symptoms viral conjunctivitis. However, to our best knowledge, there is no in-depth report on course COVID-19 complicated by relapsing conjunctivitis or keratoconjunctivitis.A 53-year-old man confirmed developed left eye approximately 10 days after...
Abstract Background Remnant cholesterol is receiving increasing attention because of its association with various diseases. However, there have been no studies on remnant levels and depression. Methods A cross-sectional analysis was performed based the National Health Nutrition Examination Survey (NHANES) 2005–2016. Depression assessed using a Patient Questionnaire (PHQ-9). Fasting calculated as total minus high-density lipoprotein (HDL-C) low-density (LDL-C). Logistic regression sampling...
Obesity and insulin resistance are well-known important risk factors for hypertension. This study aimed to investigate the mediating effect of triglyceride-glucose index (TyG) in association between Chinese visceral obesity (CVAI) hypertension among middle-aged older adults.
The interleukins (ILs) are a pluripotent cytokine family that have been reported to regulate ischemic stroke and cerebral ischemia/reperfusion (I/R) injury. IL-22 is member of the IL-10 superfamily plays important roles in tissue injury repair. However, effects on I/R remain unclear. In current study, we provided direct evidence treatment decreased infarct size, neurological deficits, brain water content mice subjected remarkably reduced expression inflammatory cytokines, including IL-1β,...
Complement factor H shows very strong association with Age-related Macular Degeneration (AMD), and recent data suggest that multiple causal variants are associated disease. To refine the location of disease variants, we characterized in detail structural variation at CFH its paralogs, including two copy number polymorphisms (CNP), CNP147 CNP148, several rare deletions duplications. Examination 34 AMD-enriched extended families (N = 293) AMD cases (White N 4210 Indian 134; Malay 140) controls...
Early assessment of carotid atherosclerotic plaque characteristics is essential for cardiovascular disease (ASCVD) risk stratification and prediction. We aimed to identify different trajectories lipid profiles investigate the association with atherosclerosis (CAS) progression in a large, longitudinal cohort Chinese population.10,412 participants aged ≥18 years ≥2 times general health checkups were included this longitudinally prospective study at Peking University Third Hospital. used latent...
Background Detecting and segmenting intracranial aneurysms (IAs) from angiographic images is a laborious task. Objective To evaluates novel deep-learning algorithm, named vessel attention (VA)-Unet, for the efficient detection segmentation of IAs. Methods This retrospective study was conducted using head CT angiography (CTA) examinations depicting IAs two hospitals in China between 2010 2021. Training included cases with subarachnoid hemorrhage (SAH) arterial stenosis, common accompanying...
Aim: Despite the well-documented pathogenic role of insulin resistance (IR) and hypertension in nephropathy progression, prognostic value estimated glucose disposal rate (eGDR) for incident renal dysfunction remains unclear. This population-based longitudinal analysis specifically examined eGDR-renal relationship middle-aged elderly populations, with a particular focus on potential mediating systolic blood pressure (SBP) based nationwide study. Methods: Utilizing data from 8,136 participants...