A5042453764- Thyroid Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Disease Prevention
- Hormonal Regulation and Hypertension
- Atrial Fibrillation Management and Outcomes
- Myasthenia Gravis and Thymoma
- Obstructive Sleep Apnea Research
- Cardiac Health and Mental Health
- Cardiac Arrhythmias and Treatments
- Preterm Birth and Chorioamnionitis
- Neuroscience of respiration and sleep
- Adipokines, Inflammation, and Metabolic Diseases
- Lipoproteins and Cardiovascular Health
- Inflammatory Biomarkers in Disease Prognosis
- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Pituitary Gland Disorders and Treatments
- Erythropoietin and Anemia Treatment
- Cardiovascular Disease and Adiposity
- Rheumatoid Arthritis Research and Therapies
- Microbial Metabolism and Applications
- Regulation of Appetite and Obesity
- Acute Myeloid Leukemia Research
Fujian Medical University
2020-2024
Lanzhou University
2024
Tianjin University of Traditional Chinese Medicine
2022-2023
Hebei Medical University
2023
Tianjin Medical University General Hospital
2022
IBM (United States)
2022
Tianjin Chest Hospital
2021-2022
Xinjiang Medical University
2012-2021
Weatherford College
2021
First Hospital of Shijiazhuang
2021
Abstract Background Triglyceride glucose (TyG) index is a new marker associated with atherosclerosis. This study aimed to assess the association between TyG and severity of coronary artery disease (CAD) in patients heart (CHD) further explore CAD different metabolic states. Methods multi-centre retrospective included 731 CHD January 1, 2014 September 30, 2020 China. All were stratified into groups based on tertiles (T1: 5.48 ≤ 7.17; T2: 7.18 7.76; T3: 7.77 10.82). The number diseased vessels...
Red cell distribution width/albumin ratio (RAR) is thought to be associated with the prognosis of a variety diseases, including diabetes and heart failure. To date, no studies have focused on relationship between RAR carotid plaque in patients coronary disease (CHD).A total 10,267 CHD were divided according quartiles (Q1: ≤ 2.960; Q2: 2.960 < 3.185; Q3: 3.185 3.441; Q4: ≥ 3.441). Logistic regression was used analyze plaques patients. The sex, age glucose regulation state groups also...
Abstract Objective: This study aimed to explore the effects of Chinese patent medicine (CPM) in reducing incidence major adverse cardiovascular events (MACE) patients with coronary heart disease (CHD) angina pectoris and improving clinical effectiveness provide evidence for its use as adjuvant therapy. Methods: Twenty-eight thousand five hundred seventeen hospitalized CHD from 6 hospitals were divided into CPM group ( n = 11,374) non-CPM 17,143) evaluate MACE, including myocardial...
Context Thyroid hormones influence glucose homeostasis through central and peripheral regulation. To date, the association between thyroid hormone sensitivity elevated blood (EBG) in patients with coronary heart disease (CHD) remains unknown. The purpose of this study was to investigate risk EBG CHD, further explore their different sexes ages. Methods This large multicenter retrospective included 30,244 CHD (aged 30–80 years) 1 January 2014 30 September 2020. Parameters representing were...
Abstract Background Accurate prediction of preterm birth (PTB) is still difficult, mostly because the multifactorial etiology PTB. Previous studies have been focused on PTB in symptomatic women or those presenting with threatened labor. We aimed to study whether complete blood count (CBC) parameters at 20‐30 weeks pregnancy can predict asymptomatic Methods In this retrospective case‐control study, and term delivery groups were matched by propensity score‐matched (PSM) analysis. Baseline data...
This study explored the relationship between monocyte-to-lymphocyte ratio (MLR) as well other leukocyte-derived ratios and carotid plaques in patients with coronary heart disease (CHD).A total of 12,093 CHD were selected research participants. Leukocyte-derived assessed this included neutrophil-to-lymphocyte (NLR), derived NLR (dNLR), MLR, platelet-to-lymphocyte (PLR), white blood cell-to-mean platelet volume (WMR), lymphocyte×neutrophil/104 (MNM), systemic immune inflammation index (SII),...
Matrix metalloproteinase-3 (MMP-3) can mediate the occurrence and development of rheumatoid arthritis (RA).The MMP3 promoter gene exhibits polymorphism with 5A/6A alleles.We investigated correlation between expression RA to provide an objective basis for prognosis evaluation.We enrolled 80 patients healthy subjects.Enzyme-linked immunosorbent assay was used detect MMP-3 serum levels, pyrosequencing test genotypes, realtime polymerase chain reaction determined mRNA levels.Compared control...
Objective Autonomic imbalance plays a crucial role in obstructive sleep apnea (OSA) associated atrial fibrillation (AF). Here, we investigated the potential neural mechanism of AF induced by OSA. Methods Ten dogs were divided into control group (n = 5) and OSA 5). The chronic model was established repeat apnea-ventilation cycles for 4 hours day 12 weeks. During process establishment, arterial blood gases, effective refractory period (AERP), inducibility, normalized low-frequency power...
Aim: This study aimed to elucidate the relationship between prognostic nutrition index (PNI) of patients with coronary heart disease (CHD) and New York Heart Association (NYHA) classification complex PNI combined body mass (BMI) NYHA classification. Methods: The was applied 17,413 consecutive CHD. Patients were divided into three groups according PNI: normal (PNI ≥ 38), moderate malnutrition (35 < severe ≤ 35). A total 2,052 CHD BMI selected stratified by subgroups nutritional status BMI....
We investigated the association between anemia status and risk of heart failure (HF) in patients with coronary disease (CHD) based on a multi-center, large-sample retrospective cross-sectional study including 89,207 patients. Heart was categorized as HF reduced ejection fraction (HFrEF), preserved (HFpEF), mid-range (HFmrEF). In multi-adjusted models, compared without anemia, mild (odds ratio [OR] 1.71; 95% confidence interval [CI] 1.53-1.91; P < .001), moderate (OR 3.68; CI, 3.25-4.17;...
Trastuzumab has improved survival rates in human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC), but drug resistance leads to treatment failure. Natural killer (NK) cell-mediated antibody-dependent cell cytotoxicity (ADCC) represents an essential antitumor immune mechanism of trastuzumab. Traditional Chinese medicine (TCM) been used for centuries treat diseases because its capacity improve responses. Xianling Lianxia formula (XLLXF), based on the principle...
The aim of this study was to establish a rapid atrial pacing-induced canine model fibrillation in studying the effects low-level vagus nerve stimulation (LLVNS) on and underlying mechanisms for those effects. Adult beagle dogs were randomly assigned 3 groups: sham operation group (sham group), fast left appendage 12-hour pacing (pacing + LLVNS (LLVNS group). All underwent tests their right effective refractory period at various time points, after which they killed, samples anterior...
To observe the influence of remote ischemic preconditioning (R-IPC) and perconditioning (R-IPER) on lower limbs rabbits with lung allograft ischemia-reperfusion injury (IRI).Sixty were randomly divided into one four groups: control (C), classic (C-IPC), R-IPC, R-IPER. The allogeneic transplantation model was established in rabbits, protective effects R-IPC R-IPER transplanted lungs determined compared to (C-IPC) IRI. Changes blood oxygen measured each group before after transplantation....
Myasthenia gravis (MG) is a devastating acquired autoimmune disease that can seriously affect the patient's quality of life. It also common complication thymoma. Previous studies have shown docetaxel alleviates myasthenic symptoms in thymoma with MG (TMG). However, little known about protein expression profiles and biomarkers for efficacy after treatment. We recruited 9 healthy controls 30 patients TMG serum proteomics study data-independent acquisition (DIA) technology. further additional...
This study aimed to examine the association between hemoglobin glycation index (HGI) and carotid artery plaque (CAP) in patients with coronary heart disease (CHD). We conducted a cross-sectional analysis of 10,778 CHD. The participants were divided into three groups by HGI tertiles (T1 HGI<-0.44, T2 -0.44 ≤ 0.15, T3 HGI>0.15). presence CAP was used diagnose ultrasonography. Logistic regression analyze CAP. also assessed according sex, age, smoking status, drinking status. further ultrasound...
The aim of our study was to investigate the association IgH and TCRγ gene rearrangements in hematological malignancies with disease clinical application.IgH were determined 69 paraffin bone marrow specimens SYBR Green I fluorescent dye RQ-PCR method, including 21 paraffin-embedded tissues onset cases 48 samples, representing 15 ALL 25 AML cases.After chemotherapy, 8 NHL; 10 negative control group healthy people.Among cases, rearrangement occurred 80.0%, 46.7%, ©FUNPEC-RP...