A5020776161- Liver Disease Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet, Metabolism, and Disease
- Diet and metabolism studies
- Cardiovascular Disease and Adiposity
- Asthma and respiratory diseases
- Adipose Tissue and Metabolism
- Lipid metabolism and disorders
- Fatty Acid Research and Health
- Obstructive Sleep Apnea Research
- Respiratory Support and Mechanisms
- Adipokines, Inflammation, and Metabolic Diseases
- Neuroscience of respiration and sleep
- Vitamin D Research Studies
- Inhalation and Respiratory Drug Delivery
- Sleep and related disorders
- Diabetes Management and Research
- Metabolism, Diabetes, and Cancer
- Obesity and Health Practices
- Peroxisome Proliferator-Activated Receptors
- Obesity, Physical Activity, Diet
- Pancreatitis Pathology and Treatment
- IL-33, ST2, and ILC Pathways
- Long-Term Effects of COVID-19
All India Institute of Medical Sciences
2016-2025
University of Alabama at Birmingham
2023-2025
Diabetes Foundation
2012-2024
National Diabetes Obesity and Cholesterol Foundation
2011-2024
All India Institute of Medical Sciences Bhopal
2019-2021
All India Institute of Medical Sciences Raipur
2019-2021
Care India
2021
Karnataka Medical Council
2019
Institute of Genomics and Integrative Biology
2011-2015
Council of Scientific and Industrial Research
2013-2015
Objective To assess the prevalence of abdominal obesity including intra-abdominal and subcutaneous adiposity along with other cardiometabolic risk factors in urban Asian Indians living New Delhi. Methods We conducted a cross-sectional epidemiological descriptive study 459 subjects (217 males 242 females), representing all socio-economic strata The anthropometric profile [body mass index (BMI), waist circumference (WC) skinfold thickness], fasting blood glucose (FBG) lipid were recorded....
Individuals at risk for chronic obstructive pulmonary disease (COPD) but without spirometric airflow obstruction can have respiratory symptoms and structural lung on chest computed tomography. Current guidelines recommend COPD diagnostic schemas that do not incorporate imaging abnormalities. To determine whether a multidimensional schema includes tomographic abnormalities identifies additional individuals with disease. This cohort study included 2 longitudinal cohorts: the Genetic...
Aim and objective Systemic inflammation has been documented in obstructive sleep apnea (OSA). However studies on childhood OSA systemic are limited. This study aimed to determine the relation between overweight/obese children various inflammatory markers. Material methods In this cross sectional study, we enrolled 247 overweight/ obese from pediatric outpatient services. We evaluated demographic clinical details, anthropometric parameters, body composition estimation of cytokines such as...
Abstract Vitamin D deficiency may contribute to etiology of type 2 diabetes in Asian Indians. The objectives this study was evaluate effect vitamin supplementation on glycemic profile and body composition prediabetic deficient overweight/obese Indian women. In open-label randomized placebo-controlled trial (78 weeks duration), 121 females (aged 20–60 years) with prediabetes were randomly allocated intervention (n, 61) placebo 60) groups. primary outcome variables fasting blood glucose (FBG),...
Accumulating data implicate interleukin (IL)-33, a proinflammatory cytokine released locally upon epithelial cell damage, in the pathogenesis of COPD. In phase 2 study, itepekimab, human monoclonal antibody against IL-33, reduced exacerbations and improved lung function subgroup analysis former smokers with COPD an acceptable safety profile.
Objectives Association between sub-clinical inflammation and non-alcoholic fatty liver disease (NAFLD) has not been studied in Asian Indians. In this case-control study, we aimed to analyse association of NAFLD with the metabolic profile Indians north India. Methods Ultrasound diagnosed 120 cases were compared 152 healthy controls without NAFLD. Anthropometric [body mass index (BMI), waist circumference (WC), hip (HC)], high-sensitivity C-reactive protein (hs-CRP), [fasting blood glucose...
Objective To evaluate body fat patterning and phenotype including hepatic pancreatic volume of non-obese (BMI: < 25 kg/m2) Asian Indians with type 2 diabetes residing in North India. Methods Non-obese patients (n = 93) non-obese, normo-glycemic subjects 40) were recruited. BMI, waist & hip circumferences, skinfold thickness at 8 sites, fat, lean mass detailed abdominal evaluation [total total subcutaneous (superficial, deep, anterior, posterior), intra-abdominal (intra-peritoneal,...
Abstract Context Excess hepatic and pancreatic fat may contribute to hyperglycemia. Objective The objective of this study was examine the effect dapagliflozin (an SGLT2 inhibitor) on anthropometric profile, liver, in patients with type 2 diabetes mellitus (T2DM). Methods This is an observational interventional paired design without a control group. Patients (n = 30) were given 10 mg/day (on top stable dose metformin and/or sulfonylureas) for 120 days. Changes anthropometry (circumferences...
The association of the rs738409 polymorphism patatin-like phospholipase-3 (PNPLA3) with nonalcoholic fatty liver disease (NAFLD) has been suggested in other populations, but not Asian Indians. We investigated PNPLA3 clinical, anthropometric, and biochemical profiles Indians NAFLD.In this case-control study, 162 cases 173 controls were recruited. Abdominal ultrasound, anthropometry, determined. Fasting insulin levels values for homeostasis model assessment resistance (HOMA-IR) Polymerase...
The aim of this study was to compare the discriminatory ability body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height (WHtR) in identifying presence cardiometabolic risk factors Asian Indians.This cross-sectional involved 509 subjects (278 males 231 females) aged 20-60 years from New Delhi, India. Measurements included complete clinical examination, blood pressure, weight, height, WC, BMI, WHR WHtR, fasting glucose, lipid profile, insulin levels....
Introduction: For low-income and middle-income countries, kidney illness death from renal failure are significant, but little recorded, burdens. Questionnaires being employed more often to determine patients' perceptions concerning medical non-medical care. A combination of knowledge, attitude, practices towards can greatly impact a person's ability effectively manage their condition lead fulfilling life despite the challenges posed by this condition. Methodology: KAP (Knowledge, Attitude...
Obesity is associated with high levels proinflammatory cytokines like tumour necrosis factor alpha (TNF-α), which may play an important role in the genesis of insulin resistance. We evaluated relationship -308G/A polymorphism TNF-α gene obesity and resistance Asian Indians north India.This cross-sectional study included 151 apparently healthy individuals (79 males, 72 females) 18-50 yrs age from New Delhi, India. Body composition by dual-energy x-ray absorptiometry (DEXA) abdominal fat...