- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Aortic aneurysm repair treatments
- Vascular Procedures and Complications
- MRI in cancer diagnosis
- Cerebrovascular and Carotid Artery Diseases
- Cancer Research and Treatments
- Vascular Anomalies and Treatments
- Pulmonary Hypertension Research and Treatments
- Gastrointestinal disorders and treatments
- Renal cell carcinoma treatment
- Tuberous Sclerosis Complex Research
- Transplantation: Methods and Outcomes
- Pancreatic and Hepatic Oncology Research
- Peripheral Artery Disease Management
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Abdominal vascular conditions and treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Aortic Disease and Treatment Approaches
- Intracranial Aneurysms: Treatment and Complications
- Central Venous Catheters and Hemodialysis
- Cyclone Separators and Fluid Dynamics
KU Leuven
2016-2025
Universitair Ziekenhuis Leuven
2022
Onze Lieve Vrouwziekenhuis Hospital
2014-2021
Royal Marsden NHS Foundation Trust
2020
Hôpital d'Instruction des Armées Clermont-Tonnerre
2013
Background and aims A complete understanding of disease pathophysiology in advanced liver is hampered by the challenges posed clinical specimen collection. Notably, these patients, a transjugular biopsy (TJB) only safe way to obtain tissue. However, it remains unclear whether successful sequencing this extremely small fragile tissue can be achieved for downstream characterization hepatic landscape. Methods Here we leveraged in-house available single-cell RNA-sequencing (scRNA-seq)...
Abstract Objectives Percutaneous liver biopsy (PLB) poses specific challenges in oncological patients such as bleeding and tumour seeding. This study’s aim was to compare a coaxial (C-PLB) non-coaxial (NC-PLB) technique terms of diagnostic yield, safety seeding risk image-guided PLB techniques an setting. Methods Local research committee approval obtained for this single-site retrospective study. Patients who underwent between November 2011 December 2017 were consecutively included. Medical...
The purpose of this study was to analyze the safety, technical success and clinical outcome percutaneous intranodal ethiodized oil (Lipiodol®) based lymphangiography (L-LAG) for management refractory pelvic lymphoceles or chylous ascites using high doses oil. Thirty-four patients presenting with symptomatic, postoperative lymphocele referred theranostic, inguinal, L-LAG treatment between May 2018 November 2021 were retrospectively included. There 21 men 13 women, a mean age 62.7 ± 16.2...
Background & aimsSpontaneous portosystemic shunts (SPSS) develop frequently in liver cirrhosis. Changes over time and the effect of aetiological interventions on SPSS are unknown, so we aimed to explore these variables evolution.MethodsCirrhotic patients from Baveno VI-SPSS cohort were selected provided there was a follow-up abdominal computed tomography (CT) or magnetic resonance imaging (MRI). Clinical laboratory data collected at baseline follow-up. Imaging tests reviewed, evaluating...
To evaluate the safety and efficacy of microvascular plug (MVP) for selective renal artery embolization.Retrospective review was performed on a cohort 6 patients undergoing embolization using MVP between July 2015 August 2018. Patients' demographics, indication embolization, technical details procedure, clinical events were gathered from patients' electronic medical records.The underwent with iatrogenic vascular injuries (n = 3), traumatic 2), elective an angiomyolipoma 1), in native kidneys...
Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer. At its intermediate, unresectable stage, HCC typically treated by local injection embolizing microspheres in hepatic arteries to selectively damage tumor tissue. Interestingly, computational fluid dynamics (CFD) has been applied increasingly elucidate impact clinically variable parameters, such as location, on downstream particle distribution. This study aims reduce cost CFD approaches introducing a novel...
Background: Although a CT scan is often performed after functional endoscopic sinonasal surgery (FESS) in patients with chronic rhinosinusitis, its role hasn`t been firmly established. The goal of this study to investigate the correlation between symptoms and findings before FESS for rhinosinusitis. In addition, interobserver agreement both aerial volumetry score assessed. Methods: Thirty-three surgically treated rhinosinusitis were included prospective study. Conventional modified...
TIPS placement is an effective, possibly life-saving, treatment for complications of portal hypertension. The pressure shift induced by the stent can lead to cardiac decompensation (CD). We investigated incidence CD, possible variables associated with CD and validity Toulouse algorithm risk prediction post-TIPS.
Abstract Background The aim of the study was to retrospectively evaluate symptom control, tumour response, and complication rate in patients with liver-predominant metastatic neuroendocrine tumours treated transarterial chemoembolization using doxorubicin-eluting superabsorbent polymer (SAP) microspheres. Patients methods liver metastases who underwent hepatic SAP-microspheres (50–100 μm Hepasphere/Quadrasphere Microsphere® particles, Merit Medical, South Jordan, Utah, USA) were included...
Combination therapy using a BRAF and MEK inhibitor significantly improves both progression-free overall survival in patients with V600-mutated stage IV melanoma. Dual MAPK inhibition achieves an objective response the majority of patients. We present case woman V600E-mutated malignant melanoma rapidly progressing liver, bone, lymph node metastases. The patient commenced dabrafenib trametinib clinical biochemical signs after 2 days. On day 3 she developed grade liver hemorrhage, which was...