Christopher J. Holmes
A5062167630- Insect behavior and control techniques
- Forensic Entomology and Diptera Studies
- Diptera species taxonomy and behavior
- Insect-Plant Interactions and Control
- Mosquito-borne diseases and control
- Hemiptera Insect Studies
- Research on scale insects
- Phytoplasmas and Hemiptera pathogens
- Insect symbiosis and bacterial influences
- Agricultural pest management studies
- Plant Parasitism and Resistance
- Insect Resistance and Genetics
- Insect and Arachnid Ecology and Behavior
- Physiological and biochemical adaptations
- Malaria Research and Control
- Viral Infections and Vectors
- Insect Pest Control Strategies
- Polar Research and Ecology
- Vector-borne infectious diseases
- RNA modifications and cancer
- RNA Research and Splicing
- Microbial Community Ecology and Physiology
- RNA and protein synthesis mechanisms
- Animal Behavior and Reproduction
- Study of Mite Species
University of Cincinnati
2017-2025
Abstract Background The Hemiptera (aphids, cicadas, and true bugs) are a key insect order, with high diversity for feeding ecology excellent experimental tractability molecular genetics. Building upon recent sequencing of hemipteran pests such as phloem-feeding aphids blood-feeding bed bugs, we present the genome sequence comparative analyses centered on milkweed bug Oncopeltus fasciatus , seed feeder family Lygaeidae. Results 926-Mb is well represented by current assembly official gene set....
Abstract Current insights into the mosquito dehydration response rely on studies that examine specific responses but ultimately fail to provide an encompassing view of biology. Here, we examined underlying changes in biology mosquitoes associated with dehydration. Specifically, show increases blood feeding northern house mosquito, Culex pipiens , which was result both higher activity and a greater tendency land host. Similar observations were noted for Aedes aegypti Anopheles quadrimaculatus...
Abstract Background The western flower thrips, Frankliniella occidentalis (Pergande), is a globally invasive pest and plant virus vector on wide array of food, fiber, ornamental crops. underlying genetic mechanisms the processes governing thrips biology, feeding behaviors, ecology, insecticide resistance are largely unknown. To address this gap, we present F. draft genome assembly official gene set. Results We report first sequence for any member insect order Thysanoptera. Benchmarking...
Abstract Background Halyomorpha halys (Stål), the brown marmorated stink bug, is a highly invasive insect species due in part to its exceptionally high levels of polyphagy. This also nuisance overwintering human-made structures. It has caused significant agricultural losses recent years along Atlantic seaboard North America and continental Europe. Genomic resources will assist with determining molecular basis for this species’ feeding habitat traits, defining potential targets pest...
Abstract Background The stable fly, Stomoxys calcitrans , is a major blood-feeding pest of livestock that has near worldwide distribution, causing an annual cost over $2 billion for control and product loss in the USA alone. Control these flies been limited to increased sanitary management practices insecticide application suppressing larval stages. Few genetic molecular resources are available help developing novel methods controlling flies. Results This study examines fly biology by...
The mosquito midgut is an important site for bloodmeal regulation while also acting as a primary pathogen exposure within the mosquito. Recent studies show that to dehydrating conditions alters bloodfeeding behaviors well post-feeding regulation, likely altering how pathogens interact with Unfortunately, few have explored underlying dynamics between dehydration and utilization, overall impact on disease transmission remains veiled. In this study, we find dehydration-based feeding in yellow...
ABSTRACT The mosquito Aedes aegypti is a competent vector of multiple pathogens, including dengue, Zika, yellow fever, chikungunya, and Mayaro viruses. Ae. highly invasive currently present in the Americas, Oceania, Asia, Europe, but its distribution pathogens it transmits are expected to change due climate change. Relative humidity (RH) an environmental variable that affects biology can differ between location, habitat, season, with mosquitoes facing significant variation RH during their...
Mosquito-borne diseases have caused more than 1 million deaths each year. There is an urgent need to develop effective way reduce mosquito-host interaction mitigate disease transmission. Sugar diets long been linked abnormal physiology in animals, making them potential candidates for mosquito control. Here, we show the impact of sugar on humidity preference and survival Aedes aegypti (Gainesville) Culex pipiens (Buckeye). Two-choice assays with high low relative (80% 50% RH) that...
Abstract The Antarctic midge, Belgica antarctica , is a wingless, non-biting midge endemic to Antarctica. Larval development requires at least 2 years, but adults live only weeks. nonfeeding mate in swarms and females die shortly after oviposition. Eggs are suspended gel of unknown composition that expressed from the female accessory gland. This project characterizes molecular mechanisms underlying reproduction this by examining differential gene expression whole males, females, larvae, as...
Abstract Background The Hemiptera (aphids, cicadas, and true bugs) are a key insect order, with high diversity for feeding ecology excellent experimental tractability molecular genetics. Building upon recent sequencing of hemipteran pests such as phloem-feeding aphids blood-feeding bed bugs, we present the genome sequence comparative analyses centered on milkweed bug Oncopeltus fasciatus , seed feeder family Lygaeidae. Results 926-Mb is well represented by current assembly official gene set....
ABSTRACT Background The western flower thrips, Frankliniella occidentalis (Pergande), is a globally invasive pest and plant virus vector on wide array of food, fiber ornamental crops. While there are numerous studies centered thrips biology, feeding behaviors, ecology, insecticide resistance, the underlying genetic mechanisms processes governing these areas research largely unknown. To address this gap, we present F. draft genome assembly official gene set. Results We report first sequence...
An amendment to this paper has been published and can be accessed via the original article.
Off-host periods are critical for ticks, representing a period when environmental stress, particularly dehydration, can impact tick survival. To prevent ticks must be able to detect and move into high humidity areas allow water vapor uptake. Ionotropic receptor 93a (Ir93a), which is highly expressed in the front forelegs (location of Haller , s organ), increases expression following suggesting role detection. Although organ suggested as site detection has not been extensively examined. Here,...
Abstract Mosquitoes are prone to dehydration and respond this stress through multiple mechanisms, but previous studies have examined very specific responses fail provide an encompassing view of the role that has on mosquito biology. This study underlying changes in biology northern house mosquito, Culex pipiens , associated with short bouts dehydration. We show increased blood feeding propensity mosquitoes, which was result both enhanced activity a higher tendency land host. exposed...
Abstract The Antarctic midge, Belgica antarctica , is a wingless, non-biting midge endemic to Antarctica. Larval development requires at least two years, but adult life lasts only weeks. nonfeeding adults mate in swarms and females die shortly after oviposition. Eggs are suspended gel of unknown composition that expressed from the female accessory gland. This project characterizes molecular mechanisms underlying reproduction this by examining differential gene expression whole males,...
Abstract The mosquito Aedes aegypti is a competent vector of multiple pathogens including dengue, Zika, yellow fever, chikungunya, and Mayaro viruses. Ae. highly invasive currently present in the Americas, Oceania, Asia, Europe, but its distribution it transmits are expected to change due climate change. Relative humidity an environmental variable that affects biology can differ between location, habitat, season, with mosquitoes facing significant variation relative during their lifespan....
Mosquitoes such as