A5029419484- Genetic factors in colorectal cancer
- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer-related molecular mechanisms research
- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Nutrition and Health in Aging
- Cancer Risks and Factors
- Cardiac Imaging and Diagnostics
- Exercise and Physiological Responses
- RNA Research and Splicing
- Cardiovascular and exercise physiology
- Physical Activity and Health
- Cardiac Health and Mental Health
- Venous Thromboembolism Diagnosis and Management
- Inflammatory Biomarkers in Disease Prognosis
- Acute Myocardial Infarction Research
- Acute Ischemic Stroke Management
- Cancer-related cognitive impairment studies
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Cardiac Fibrosis and Remodeling
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Health and Risk Factors
- Cardiovascular Health and Disease Prevention
- Acute Lymphoblastic Leukemia research
The University of Texas MD Anderson Cancer Center
2017-2024
LabCorp (United States)
2022-2023
Susan G. Komen Breast Cancer Foundation
2019
MIND Research Institute
2018
Cornell University
2018
Weill Cornell Medicine
2018
Columbia University
2018
Memorial Sloan Kettering Cancer Center
2018
Wake Forest University
2018
University of Vermont
2018
Cardiovascular disease is a competing cause of death in patients with cancer early-stage disease. This elevated cardiovascular risk thought to derive from both the direct effects therapies and accumulation factors such as hypertension, weight gain, cigarette smoking, loss cardiorespiratory fitness. Effective viable strategies are needed mitigate this population; multimodal model cardiac rehabilitation may be potential solution. statement American Heart Association provides an overview...
Sedentary behavior is associated with several health outcomes, including diabetes, cardiovascular disease, and all-cause mortality. Less known about the association between objectively measured sedentary cancer mortality, as well physical activity.To examine accelerometer-measured (total volume accrual in prolonged, uninterrupted bouts) mortality.A prospective cohort study conducted contiguous US included 8002 black white adults aged 45 years or older enrolled Reasons for Geographic Racial...
Background: A robust literature demonstrates that coronary artery calcification (CAC) and cardiorespiratory fitness (CRF) are independent predictors of cardiovascular disease (CVD) events. Much less is known about the joint associations CRF CAC with CVD risk. In setting high CAC, versus low has been associated decreased The goal this study was to assess effect continuous levels on risk in increasing burden. Methods: We studied 8425 men without clinical who underwent preventive medicine...
Physical activity (PA) is a known behavior to reduce cancer risk and improve survivorship, yet adherence PA guidelines poor among the general population survivors. The purpose of this study was determine extent which patients referred for exercise consultation within clinical prevention setting were meeting aerobic resistance physical identify factors associated with guideline adherence. Between 2013 2015, survivors interviewed by an physiologist Integrative Health Program at University...
Among 29,701 Black and White participants aged 45 years older in the Reasons for Geographic Racial Difference Stroke (REGARDS) study, allostatic load (AL) was defined as sum score of established baseline risk-associated biomarkers which exceeded a set cutoff point. Cox proportional hazard regression utilized to determine association AL with all-cause cancer-specific mortality, analyses stratified by body-mass index, age group, race. At baseline, Blacks had higher compared Whites (Black mean...
<h3>Objective</h3> We aimed to evaluate the association between cancer and cerebrovascular disease in a prospective cohort study with adjudicated diagnoses. <h3>Methods</h3> analyzed participants from Reasons for Geographic Racial Differences Stroke (REGARDS) who were 45 years older had Medicare coverage 365 days before their baseline visit. Participants history of or events excluded. The time-dependent exposure was new diagnosis malignant identified through claims algorithms. prospectively...
Abstract Purpose Preclinical evidence suggests that natural killer cell (NK-cell) function and myokines facilitate the protective effects of exercise for breast cancer prevention. Since higher-intensity acutely promotes greater mobilization larger changes in NK-cell cytotoxicity than lower-intensity, high-intensity interval training (HIIT) might offer increased immune protection compared to moderate-intensity continuous-training (MICT). This study a 12-week HIIT program MICT usual care on...
Objective This study examined whether metabolic health status is associated with risk of cancer mortality and this varies by body mass index (BMI) category. Methods A prospective 22,514 participants from the Reasons for Geographic Racial Differences in Stroke (REGARDS) cohort was performed. Metabolically unhealthy defined as having three or more following: (1) elevated fasting glucose, (2) high triglycerides, (3) dyslipidemia, (4) hypertension, (5) waist circumference. Participants were...
Guidelines recommend venous thromboembolism (VTE) risk assessment in outpatients with cancer and pharmacologic thromboprophylaxis selected patients at high for VTE. Although validated stratification tools are available, < 10% of oncologists use a tool, rates VTE prophylaxis high-risk low practice. We hypothesized that implementation systems-based program uses the electronic health record (EHR) offers personalized recommendations would increase initiating outpatient chemotherapy.Venous...
Men diagnosed with prostate cancer are at risk for competing morbidity and mortality due to cardiometabolic disease given their advanced age diagnosis, high prevalence of pre-existing factors, receipt systemic therapy that targets the androgen receptor (AR). Expert panels have stressed importance assessment in clinic proposed evaluating key risks using consensus paradigms. Yet, there is a gap real-world evidence implementation comprehensive care men cancer.This retrospective, descriptive...
PurposeCardiotoxicities induced by cancer therapy can negatively affect quality of life and survival. We investigated whether high-sensitivity cardiac troponin T (hs-cTnT) levels could serve as biomarker for early detection adverse events (CAEs) after chemoradiation (CRT) non-small cell lung (NSCLC).Methods MaterialsThis study included 225 patients who received concurrent platinum taxane-doublet chemotherapy with thoracic radiation to a total dose 60 74 Gy NSCLC. All were evaluated CAEs; 190...
Abstract Purpose: Lynch syndrome (LS) is a hereditary condition with high lifetime risk of colorectal and endometrial cancers. Exercise non-pharmacologic intervention to reduce cancer risk, though its impact on patients LS has not been prospectively studied. Here, we evaluated the 12-month aerobic exercise cycling in biology immune system carriers. Patients Methods: To address this, enrolled 21 onto non-randomized, sequential assignation, clinical trial assess effect program that included...
Postmenopausal women are at risk of fractures owing to osteoporosis, which is worsened by low oestrogen. Bisphosphonates like ibandronate, zoledronic acid, alendronate, and risedronate limit bone resorption increase density, reducing fracture risk. Although atypical femur (AFFs) uncommon, they associated with dangerous complications long-term bisphosphonate therapy. Early identification before occur crucial minimizing complications. The review examines bisphosphonate-related medical issues...
Immunosenescence is described as age-associated changes within the immune system that are responsible for decreased immunity and increased cancer risk. Physically active individuals have fewer 'senescent' more naïve T-cells compared to their sedentary counterparts, but it not known if exercise training can rejuvenate 'older looking' T-cell profiles. We determined effects of 12-weeks supervised on frequency subtypes in peripheral blood relationships with circulating levels muscle-derived...
The American College of Cardiology Foundation, in collaboration with the Society for Cardiovascular Angiography and Interventions key specialty subspecialty societies, conducted a review common clinical scenarios where diagnostic catheterization is frequently considered.
Whether cardiovascular disease (CVD) risk differs according to race and cancer type among survivors of childhood or young adulthood cancers is unknown.Data from the years 1973-2011 were analyzed using Surveillance, Epidemiology, End Results (SEER) registries. Cases categorized by ICD-0-3/WHO 2008 Adolescent Young Adult classification. CVD death was determined ICD-10 codes for diseases heart, atherosclerosis, cerebrovascular diseases, other arteries. Cox proportional hazards models fitted...
Retrospective studies have reported an association between cancer and arterial thromboembolic event (ATE) risk.
Cardiovascular disease remains the leading cause of death in women. To address its determinants including persisting cardiovascular risk factors amplified by sex and race inequities, novel personalized approaches are needed grounded engagement participants research prevention.
ABSTRACT Purpose Sedentary behavior is associated with poor physical function in older adults, which can lead to accelerated skeletal muscle aging (sarcopenia) and premature mortality. We examined the independent joint effects of sedentary moderate vigorous intensity activity (MVPA) measures functioning. Methods studied 5408 participants REasons for Geographic Racial Differences Stroke study who wore a hip-mounted accelerometer over seven consecutive days (2009–2013) had self-reported...
There is a growing population of adolescent and young adult (AYA) cancer survivors (ages 15-39 years), they have an elevated risk developing cardiovascular disease (CVD). Little known about the contribution sociodemographic modifiable factors to CVD in AYA whether these differentially modulate their compared with that general population. The current study sought fill gaps.Self-reported data from US National Health Interview Survey (2009-2018) were used identify (≥2 years postdiagnosis)...
// Tomi Akinyemiju 1, 2, 3 , Justin Xavier Moore 2 Suzanne E. Judd 4 Maria Pisu 5 Michael Goodman 6 Virginia J. Howard 1 Leann Long Monika Safford 7 Susan C. Gilchrist 8 and Mary Cushman 9 Department of Epidemiology, University Alabama at Birmingham, AL, USA Comprehensive Cancer Center, Kentucky, Lexington, KY, Biostatistics, Division Preventive Medicine, Emory Rollins School Public Health, Atlanta, GA, Weill Cornell Medical College, New York, NY, Clinical Prevention Cardiology, The Texas MD...
Abstract Background Early skeletal muscle loss has been observed in adolescent and young adult (AYA) sarcoma patients undergoing treatment. Identification of individuals within the AYA populace that are at greatest risk anthracycline‐induced is unknown. Moreover, investigations which seek out underlying causes degradation during chemotherapy critical for understanding, preventing, reducing chronic health conditions associated with poor status. Methods Computed tomography (CT) scans were used...