Erica C Leifheit

ORCID: 0000-0001-9675-8913
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About
Contact & Profiles
Research Areas
  • Acute Ischemic Stroke Management
  • Cardiac Health and Mental Health
  • Stroke Rehabilitation and Recovery
  • Cerebrovascular and Carotid Artery Diseases
  • Health disparities and outcomes
  • Healthcare Systems and Public Health
  • Heart Failure Treatment and Management
  • Cardiovascular Health and Risk Factors
  • Climate Change and Health Impacts
  • Cardiovascular Health and Disease Prevention
  • Global Health Care Issues
  • Healthcare Policy and Management
  • Air Quality and Health Impacts
  • Chronic Disease Management Strategies
  • Healthcare Systems and Practices
  • Mast cells and histamine
  • Acute Myocardial Infarction Research
  • Clinical practice guidelines implementation
  • Cerebral Venous Sinus Thrombosis
  • Oropharyngeal Anatomy and Pathologies
  • Chronic Myeloid Leukemia Treatments
  • Blood Pressure and Hypertension Studies
  • Mental Health Treatment and Access
  • Sex and Gender in Healthcare
  • Antiplatelet Therapy and Cardiovascular Diseases

Yale New Haven Health System
2025

Yale University
2017-2024

Leifheit (Germany)
2018-2020

University of Kentucky
2018

Mayo Clinic in Florida
2018

Jacksonville College
2018

Harvard University
2018

Children's Hospital of Los Angeles
2007

Eckerd College
2004

Bay Pines VA Healthcare System
2004

Background: Some studies report that women are less likely to present with chest pain for acute myocardial infarction (AMI). Information on symptom presentation, perception of symptoms, and care-seeking behaviors is limited young patients AMI. Methods: We interviewed 2009 976 men aged 18 55 years hospitalized AMI at 103 US hospitals participating in the VIRGO study (Variation Recovery: Role Gender Outcomes Young Patients). Structured patient interviews during index hospitalization were used...

10.1161/circulationaha.117.031650 article EN Circulation 2018-02-19

Carotid endarterectomy and carotid artery stenting are the leading approaches to revascularization for stenosis, yet contemporary data on trends in rates outcomes limited.To describe US national performance of among Medicare beneficiaries from 1999 2014.Serial cross-sectional analysis fee-for-service aged 65 years or older 2014 using Inpatient Denominator files. Spatial mixed models adjusted age, sex, race were fit calculate county-specific risk-standardized rates. Mixed assess after...

10.1001/jama.2017.12882 article EN JAMA 2017-09-19

The importance of various inflammatory cytokines in maintaining tumor cell growth and viability is well established. Increased expression the proinflammatory cytokine macrophage migration inhibitory factor (MIF) has previously been associated with types adenocarcinoma.

10.1186/1471-2407-4-34 article EN cc-by BMC Cancer 2004-07-12

Short-term outcomes after acute myocardial infarction (AMI) have improved, but little is known about longer-term outcomes.To evaluate trends in 10-year all-cause mortality and hospitalization for recurrent AMI by demographic subgroups examine the association between recurrence mortality.Medicare fee-for-service beneficiaries who survived from 1995 to 2019. Subgroups were defined age, sex, race, dual Medicare-Medicaid-eligible status, residence health priority areas (geographic with...

10.1001/jamacardio.2022.0662 article EN JAMA Cardiology 2022-05-04

Background Patients who survive acute myocardial infarction ( AMI ) are at high risk for recurrence. We determined whether rehospitalizations after further increased of recurrent . Methods and Results The study included Medicare fee‐for‐service patients aged ≥65 years discharged alive from acute‐care hospitals in fiscal 2009–2014. outcome was within 1 year the index Clinical Classifications Software CCS used to classify into disease categories. A Cox regression model fit accounting ‐specific...

10.1161/jaha.119.014907 article EN cc-by-nc-nd Journal of the American Heart Association 2020-03-14

Introduction: A nation-wide stroke surveillance system is not available in the US, limiting analyses to identify subgroups at disproportionate risk for ischemic (IS). These data are needed help inform targeted interventions improve primary prevention high-risk populations. We assessed trends IS hospitalizations and factor prevalence by age, sex, racial/ethnic using from GWTG-Stroke. Methods: The sample included patients discharged GWTG-Stroke participating hospitals 2010-2021 with a final...

10.1161/str.56.suppl_1.tp309 article EN Stroke 2025-01-30

This study explored whether and how depression low social support mediate the association between marital stress cardiac-specific quality of life (QoL) in young adults (≤55 years) with acute myocardial infarction (AMI). Data were obtained from 1593 married/partnered AMI survivors aged 18-55 years enrolled VIRGO (2008-2012). Marital (Stockholm Stress Scale) was self-reported at 1 month post-AMI categorized as absent/moderate or severe. Significant depressive symptoms (Patient Health...

10.1097/psy.0000000000001363 article EN 2025-02-01

Background: There have been important advances in secondary stroke prevention and a focus on healthcare delivery over the past decades. Yet, data US trends recurrent are limited. We examined national regional patterns 1-year recurrence among Medicare beneficiaries hospitalized for ischemic from 2001 to 2017. Methods: This cohort study included all fee-for-service aged ≥65 years who were discharged alive with principal diagnosis of Follow-up was up 1 year through 2018. Cox models used assess...

10.1161/strokeaha.122.039438 article EN Stroke 2022-10-10

Long-term exposure to air pollutants is associated with increased stroke incidence, morbidity, and mortality; however, research on the association of pollutant poststroke hospital readmissions lacking.

10.1161/strokeaha.122.042265 article EN Stroke 2023-02-02

Background Stress experienced in a marriage or committed relationship may be associated with worse patient‐reported outcomes after acute myocardial infarction (AMI), but little is known about this association young adults (≤55 years) AMI. Methods and Results We used data from VIRGO (Variation Recovery: Role of Gender on Outcomes Young AMI Patients), an observational cohort study that enrolled individuals aged 18 to 55 years (2008–2012). Marital stress was self‐reported 1 month using the...

10.1161/jaha.123.030031 article EN cc-by-nc-nd Journal of the American Heart Association 2023-08-17

To determine whether patients who are dual eligible for Medicare and Medicaid benefits have outcomes after carotid endarterectomy (CEA) that comparable to the of those alone.

10.1212/wnl.0000000000006380 article EN Neurology 2018-09-29

Background Racial/ethnic disparities in acute stroke care may impact outcomes. We compared outcomes by race/ethnicity among elderly Medicare beneficiaries hospitals participating the FL-PR CReSD (Florida-Puerto Rico Collaboration to Reduce Stroke Disparities) registry with those not any quality improvement programs (non- QI ) Florida and Puerto (PR). Methods Results The population included fee-for-service age 65+ PR , discharged primary diagnosis of ischemic ( International Classification...

10.1161/jaha.118.009649 article EN cc-by-nc-nd Journal of the American Heart Association 2018-12-27

Background Medicaid serves as a safety net for low-income US Medicare beneficiaries with limited assets. Approximately 7.7 million Americans aged ≥65 years rely on combination of and to obtain critical medical services, yet little is known about whether these patients have worse outcomes after stroke than alone. We compared geographic patterns in dual Medicare-Medicaid eligibility ischemic hospitalizations examined dual-eligible had post-stroke those Methods identified fee-for-service who...

10.1371/journal.pone.0292546 article EN cc-by PLoS ONE 2023-10-05

Background Whether stroke patients treated at hospitals with better short-term outcome metrics have long-term outcomes is unknown. We investigated whether treatment US 30-day hospital-level was associated 1-year outcomes, including reduced mortality and recurrent stroke, for after ischemic stroke. Methods This cohort study included Medicare fee-for-service beneficiaries aged ≥65 years discharged alive from a principal diagnosis of 07/01/2015 to 12/31/2018. categorized by the treating...

10.1371/journal.pone.0289790 article EN cc-by PLoS ONE 2023-08-10

Background: 30-day readmission after ischemic stroke is an important health quality of care metric, but little known about potential race-ethnic disparities for this outcome. We examined rates and causes among Medicare beneficiaries in the NINDS-funded Florida-Puerto Rico Collaboration to Reduce Stroke Disparities (CReSD) Study. Methods: all-cause fee-for-service treated (ICD-9 433,434, 436) FL CReSD hospitals from 2010-2013. fit a Cox proportional hazards model that censored death adjusted...

10.1161/str.49.suppl_1.wp306 article EN Stroke 2018-01-22

Introduction Despite evidence supporting the benefits of marriage on cardiovascular health, impact marital/partner status long-term readmission young acute myocardial infarction (AMI) survivors is less clear. We examined association between and 1-year all-cause explored sex differences among AMI survivors. Methods Data were from VIRGO study (Variation in Recovery: Role Gender Outcomes Young Patients), which enrolled adults aged 18–55 years with (2008–2012). The primary end point was within 1...

10.1371/journal.pone.0287949 article EN cc-by PLoS ONE 2024-01-26
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