A5038242894- Vector-Borne Animal Diseases
- Animal Disease Management and Epidemiology
- Vector-borne infectious diseases
- Viral Infections and Vectors
- Agriculture and Farm Safety
- Microbial infections and disease research
- Herpesvirus Infections and Treatments
- Clostridium difficile and Clostridium perfringens research
- Rabies epidemiology and control
- Animal Behavior and Welfare Studies
- Helminth infection and control
- Animal health and immunology
- Coccidia and coccidiosis research
- Parasite Biology and Host Interactions
- Leptospirosis research and findings
- Antimicrobial Resistance in Staphylococcus
- Yersinia bacterium, plague, ectoparasites research
- Animal Diversity and Health Studies
- Veterinary Pharmacology and Anesthesia
- Viral Infections and Immunology Research
- Reproductive System and Pregnancy
- Effects of Environmental Stressors on Livestock
- Livestock Management and Performance Improvement
- Mosquito-borne diseases and control
- Brucella: diagnosis, epidemiology, treatment
Royal GD (Netherlands)
2020-2025
Netherlands Food and Consumer Product Safety Authority
2011-2024
North-West University
2024
Wageningen University & Research
2011-2024
De Gezondheidsdienst voor Dieren
2009-2022
Radboud University Nijmegen
2011-2013
Radboud University Medical Center
2011-2013
Canisius-Wilhelmina Ziekenhuis
2011
University Medical Center
2011
Utrecht University
2011
Since 1998, notifiable bluetongue virus (BTV) serotypes 1-4, 6, 8, 9, 11, and 16 have been reported in Europe. In August 2006, a (BT) outbreak caused by BTV serotype 8 began northwestern The Netherlands was declared BT-free February 2012, annual monitoring continued. On September 3, 2023, typical BT clinical manifestations sheep were notified to the Food Product Safety Consumer Authority. we confirmed infection through laboratory diagnosis; notifications of signs cattle also reported. We...
In September 2023, bluetongue virus serotype 3 (BTV-3) was identified among sheep and cattle in the Netherlands. Severe clinical signs increased mortality were reported cattle. The aim of this study to quantify impact BTV-3 on mortality, abortions premature births Netherlands 2023. Data available from 1 January 2020-31 December 2023 aggregated at herd-month level. Cattle herds assigned a status for each herd-month: 1) that notified BTV-3, 2) did not notify but located infected areas or 3)...
Abstract Q fever is a zoonosis caused by the bacterium Coxiella burnetii. One of largest reported outbreaks in humans occurred Netherlands starting 2007; epidemiologic investigations identified small ruminants as source. To determine genetic background C. burnetii domestic responsible for human outbreak, we genotyped 126 burnetii–positive samples from using 10-loci multilocus variable-number tandem-repeat analyses panel and compared them with internationally known genotypes. unique genotype...
Recently, the number of human Q fever cases in Netherlands increased dramatically. In response to this increase, dairy goats and sheep were vaccinated against Coxiella burnetii. All pregnant herds positive for culled. We identified effect vaccination on bacterial shedding by small ruminants. On day culling, samples uterine fluid, vaginal mucus, milk obtained from 957 animals 13 herds. Prevalence load reduced compared with unvaccinated animals. These effects most pronounced during their first...
Abstract Background The bluetongue virus serotype 3 (BTV‐3) outbreak in the Netherlands 2023 caused severe clinical signs ruminants. and pathological ruminants their spread during are described. Methods Data from Dutch monitoring surveillance system were available to describe findings related BTV‐3 sheep, cattle goats. During outbreak, 13 farms (five five three dairy goats) closely monitored. Results In 2023, infections confirmed by real‐time polymerase chain reaction sheep flocks ( n =...
In 2007, a human Q fever epidemic started, mainly in the south eastern part of The Netherlands with suspected indirect relation to dairy goats, and, lesser degree, sheep. This article describes prevalences Dutch goat and sheep bulk tank milk (BTM) samples, using real-time (RT) PCR ELISA. Results BTM ELISA were compared serological status individual animals, correlations history abortion determined. When results, optimal cut-off value for RT-PCR was 100 bacteria/ml. 2008, there 392 farms more...
Infections caused by Coxiella burnetii, commonly referred to as coxiellosis when occurring in animals and Query fever humans, are an important cause of abortions, decreased reproductive efficiency, subclinical infections ruminants. The organism also represents zoonotic concern associated with its ability aerosolize easily low infectious dose. Available diagnostic tests have limited sensitivity, which combined the absence treatment options approaches prevention, result difficulty managing...
Abstract Since 1998, WOAH-notifiable bluetongue virus (BTV) serotype 1, 2, 3, 4, 6, 8, 9, 11, and 16 have been reported in Europe. In mid-August, 2006, a BTV-8 outbreak started Northwestern The Netherlands was declared BT-free again February 2012 annual monitoring demonstrated BT-freedom up to 2023. On September 3 rd 2023, clinical manifestations sheep typical for BT were notified the Dutch Food Product Safety Consumer Authority. Laboratory diagnosis confirmed BTV-infection on 6 first...
In September 2023, bluetongue virus serotype 3 (BTV-3) emerged in the Netherlands, infecting over five thousand livestock farms. sheep, high morbidity and mortality rates were reported that unlike previously described outbreaks. This study aimed to quantify impact of BTV-3 small ruminant population Netherlands 2023. Sheep goat movement census data notification available from 2020 until end Data aggregated farm week level indicators calculated for lambs (<1 year) adult animals (≥1 year)....
Since 2007, Q fever has become a major public health problem in the Netherlands and goats were most likely source of human outbreaks 2008 2009. Little was known about consequences these for those professional care providers directly involved. The aim this survey to estimate seroprevalence antibodies against C. burnetii among Dutch livestock veterinarians determine possible risk factors. Single blood samples from 189 veterinarians, including veterinary students their final year, collected at...
Abortion in small ruminants can be caused by various non-infectious and infectious agents (Givens Marley 2008, Holler 2012). Several cause serious disease human beings. As a consequence, abortion results reproductive loss also have severe zoonotic implications, as became apparent 2007–2010 when Coxiella burnetii, originating from dairy goat farms with storms, one of the largest recorded community outbreaks Q fever (Roest others 2011). This outbreak stimulated development so-called one-health...
In Northwestern Europe, an epizootic outbreak of congenital malformations in newborn lambs due to infection with Schmallenberg virus (SBV) started at the end 2011. The objectives this study were describe clinical symptoms SBV infection, effect on mortality rates, and reproductive performance sheep, as well identify quantify flock level risk factors for infections resulting lambs. A case-control design was used, 93 case flocks that had notified malformed 84 control no such Overall animal...
<ns3:p>Q fever is a widespread zoonotic disease caused by the bacterium, <ns3:italic>Coxiella burnetii</ns3:italic>. In ruminants, <ns3:italic>C. burnetii</ns3:italic> can cause abortions, stillbirths, premature births, and weak offspring. As part of EU-funded Q-Net-Assess International Coordination Research on Infectious Animal Diseases (ICRAD)-project, aimed at generating most comprehensive understanding genetic variation to date determining implications this for risk, pathogenicity...
In the period from 2005 to 2009, Coxiella burnetii was a cause of abortion waves at 28 dairy goat farms and 2 sheep in Netherlands. Two years after first waves, large human Q fever outbreak started mainly same region, aborting small ruminants were regarded as most probable source. To distinguish between infected noninfected herds, surveillance program October based on PCR testing bulk tank milk (BTM) samples, which had never been described before. The aim this study analyze effectiveness...