To combat the growing threat of antibiotic resistance, environmental testing for contamination is gaining an increasing role. This study aims to develop easy-to-use assay detection fluoroquinolone levofloxacin. Levofloxacin used in human and veterinary medicine has been detected wastewater river water. An RNA aptamer against levofloxacin was selected using Capture-SELEX. The 73 nt long folds into three stems with a central three-way junction. It binds Kd 6 µM discriminates closely related...

Abstract Mesoporous ceramic materials used in applications such as catalysis, filtration, or sensing, are usually hierarchically structured. Thereby, their structural hierarchy is often inherently related to the manufacturing methods and cannot be independently locally designed along all length scales. This study combines light‐based additive bottom‐up light‐induced self‐assembly (LISA) sol‐gel chemistry engineer structured porous silica from nanoscale macroscopic object geometry. A...

The excessive use of antibiotics in food-producing animals causes a steady rise multiple antibiotic resistance foodborne bacteria. Next to sulfonamides, the most common groups are fluoroquinolones, aminoglycosides, and ß-lactams. Therefore, there is need for quick, efficient, low-cost detection procedure antibiotics. In this study, we propose an inkjet-printed aptamer-based biosensor developed fluoroquinolone ciprofloxacin. Due their extraordinary high affinity specificity, aptamers already...

Abstract Since the pandemic outbreak of Covid-19 in December 2019, several lateral flow assay (LFA) devices were developed to enable constant monitoring regional and global infection processes. Additionally, innumerable test are frequently used for determination different clinical parameters, food safety, environmental factors. common LFAs rely on non-biodegradable nitrocellulose membranes, we focused their replacement by cellulose-composed, biodegradable papers. We report development...

A simple, efficient, and repeatable combination of wax printing hot embossing is reported. This yields microfluidic channels in paper, where fluid transport driven by paper-intrinsic capillary forces takes place inside the noncompressed areas, whereas embossed wax-bonded areas serve as hydrophobic barriers laterally confining flow. Lab-made paper sheets first coated with a were hot-embossed tailor-made metal stamp. Both (e.g., grammage, fiber type) paper-extrinsic parameters force) studied...

This study presents gravure printing as a new strategy for rapid of ceramic mesoporous thin films and highlights its advantages over conventional film preparation using evaporation induced self-assembly together with dip-coating.

ABSTRACTFused filament fabrication plays an increasingly important role in modern manufacturing. Despite this, issues like deformations caused by thermal shrinkage are still common. These process failures, called warping, can easily be avoided ensuring sufficient adhesion of the printed part to build surface during manufacturing process. Nevertheless, only a few is known about factors which have impact on between and surface. Although content moisture used polymer every established...

Abstract Test strips are convenient tools for rapid, semi-quantitative analysis of a variety parameters by dipping them few seconds in sample solution followed simple colorimetric read-out. Their sensitivity is mainly determined the reactivity test dyes on reaction zone and not sufficient some applications. The detection limit commercially available free chlorine strips, example, at present low enough to confirm absence this analyte as disinfectant rinsing solutions after disinfection or...

Abstract Combinatorial sensing is especially important in the context of modern drug development to enable fast screening large data sets. Mesoporous silica materials offer high surface area and a wide range functionalization possibilities. By adding structural control, combination functional control along all length scales opens new pathway that permits larger amounts analytes being tested simultaneously for complex tasks. This study presents simple way produce mesoporous various shapes...

Flexo-and gravure-printed indium-zinc-oxide (IZO) semiconductor thin-film transistors (TFTs) with bottom-gate bottom-contact device architecture are investigated systematically. A strong dependence of the TFT characteristics is observed on number printed IZO layers and cell volume printing cylinder. White-light interferometry scanning electron microscopy data show that homogeneous only few nanometer thin films variation correlated significant differences in film morphology scale. For...

The adhesion of parts to the build surface plays a central role in Fused Filament Fabrication (FFF) process. Without sufficient adhesion, part will deform (so called warping) due thermal shrinkage, so that no defined geometries can be created. Nevertheless, there is established method measure printed and therefore it not possible targeted improve it. This article presents measurement based on DIN EN 28510-1 standard corresponding test device which makes identify optimum for filament also...

Transparent and dense dielectric Ta₂O₅ thin films are accessible <italic>via</italic> a solution based molecular approach.

Abstract 3D-bioprinting is a promising technique to mimic the complex anatomy of natural tissues, as it comprises precise and gentle way placing bioinks containing cells hydrogel. Although hydrogels expose an ideal growth environment due their extracellular matrix (ECM)-like properties, high water amount tissue like microstructure, they lack mechanical strength possess diffusion limit couple hundred micrometers. Integration electrospun fibers could hereby benefit in multiple ways, for...

The organic thin film transistor (OTFT) is an elementary part of most electronic products. A cost efficient and fast way to produce these circuits by the use mass printing techniques like flexography or gravure printing. huge amount OTFTs produced via spin-coating as a reference. morphology printed layers electrical performance are investigated. Based on investigations, dependence mobility transistor's source/drain geometry analysed explained. Analysed parameters transistors channel length,...

Fused filament fabrication, also called material extrusion, is a widespread used 3D-printing process which allows to manufacture parts with high freedom of design at low costs. A common issue the deformation during printing caused by thermal stress and an insufficient adhesion. Despite usage extrusion only few publications dealing this topic it yet nearly unknown, parameters have influence onto part adhesion nor how they interact among each other. This publication investigates between build...

The filament drive is a key part of the extrusion assembly Fused Filament Fabrication printer. This investigation examines maximum feed force and slip different driving rollers using made polylactic-acid (PLA) on test stand. stand systematically varies main process parameters: velocity, pinch between rollers, force. has characteristic dependency combined with feed-velocity-dependency, which influenced by outer diameter roller. was found to increase linearly decreases increasing nearly...

ABSTRACTFused filament fabrication, also known as material extrusion, is an additive manufacturing process used in many industries. Despite its widespread application, common issues like unwanted deformation of the part to be printed during are rarely investigated. These failures, called warping, can avoided by a sufficient adhesion between build surface and part. Although printing processes last up several days, time dependencies mechanism causing poorly understood. For this reason,...