Xuemin Shi

ORCID: 0000-0001-9781-3312
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About
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Research Areas
  • Acupuncture Treatment Research Studies
  • Traditional Chinese Medicine Studies
  • Healthcare and Venom Research
  • Neurological Disease Mechanisms and Treatments
  • Medical Research and Treatments
  • Stroke Rehabilitation and Recovery
  • Neurological Disorders and Treatments
  • Acute Ischemic Stroke Management
  • Botulinum Toxin and Related Neurological Disorders
  • Psychosomatic Disorders and Their Treatments
  • Complementary and Alternative Medicine Studies
  • Pain Management and Placebo Effect
  • Myofascial pain diagnosis and treatment
  • Dysphagia Assessment and Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurogenesis and neuroplasticity mechanisms
  • Vasculitis and related conditions
  • Multiple Sclerosis Research Studies
  • Traditional Chinese Medicine Analysis
  • Mitochondrial Function and Pathology
  • Cell Image Analysis Techniques
  • Redox biology and oxidative stress
  • Blood Pressure and Hypertension Studies
  • Biofield Effects and Biophysics

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2013-2025

Luohe Medical College
2024

Capital Medical University
2017-2023

Wuhan University
2022-2023

Beibu Gulf University
2022

University Hospital of Zurich
2019

University of Zurich
2019

Tianjin University of Traditional Chinese Medicine
2006-2017

Tianjin University
2008-2017

Beijing University of Chinese Medicine
2017

Stroke is a leading cause of death and disability worldwide. Despite improvements in acute stroke treatment, many patients only make partial or poor recovery. Therefore, there need for treatments that would further improve outcome. Danqi Piantang Jiaonang (DJ; NeuroAid), traditional Chinese medicine widely used China to recovery after stroke, has been compared with another 2 unpublished randomized clinical trials. The results these studies were pooled reanalyzed assess efficacy safety.Six...

10.1161/strokeaha.108.531616 article EN Stroke 2009-01-23

Stroke is one of the most common causes death and few pharmacological therapies show benefits in ischemic stroke. In this study, 290 patients aged 40–75 years old with first onset acute stroke (more than 24 hours but within 14 days) were treated standard treatments, then randomly allocated into an intervention group (treated resuscitating acupuncture) a control using sham-acupoints). Primary outcome measures included Barthel Index (BI), relapse up to six months. For both groups, case died,...

10.1142/s0192415x12500516 article EN The American Journal of Chinese Medicine 2012-01-01

Numerous randomized controlled trials (RCTs) of acupuncture have been conducted in recent years. The results several studies implied that was only a powerful placebo; however, certain demonstrated verum had greater effect than placebo and the mechanisms between group placebo/sham were different. Researchers attempted to investigate inherent factors may potentially influence trials. Certain problems observed RCTs also occurred other fields, including insufficient sample size, high dropout...

10.3892/etm.2015.2653 article EN Experimental and Therapeutic Medicine 2015-07-23

Acupuncture is an effective treatment for ischemic stroke (IS) and plays a key role in neurological rehabilitation after IS. can improve the clinical symptoms of various complications IS, including motor dysfunction, swallowing disorders, speech cognitive impairment, depression, insomnia, fatigue. However, mechanisms underlying effects acupuncture IS remain unclear. Available evidence suggests that may exert neuroprotective through neuroplasticity (neurogenesis synaptogenesis), angiogenesis,...

10.1097/hm9.0000000000000094 article EN cc-by-nc-nd Acupuncture and Herbal Medicine 2024-01-26

Our previous findings have demonstrated that acupuncture at the Taixi (KI3) acupoint in healthy youths can activate neurons cognitive-related cerebral cortex. Here, we investigated whether this elderly patients with mild cognitive impairment also these regions. Resting state and task-related functional magnetic resonance imaging showed pinprick senstation of differed significantly between controls. Results 20 brain regions were activated both groups participants, including bilateral anterior...

10.4103/1673-5374.135319 article EN cc-by-nc-sa Neural Regeneration Research 2014-01-01

To investigate the relationship between dynamic changes in neutrophil-to-lymphocyte ratio (NLR) and neurological recovery noninfected patients with acute cerebral infarction after thrombolysis. A retrospective analysis was conducted on 277 stroke Least absolute shrinkage selection operator (LASSO) regression used to identify factors influencing recovery, 1:1 propensity matching performed groups compare National Institutes of Health Stroke Scale (NIHSS) score, muscle strength, NLR treatment....

10.1002/brb3.70373 article EN cc-by Brain and Behavior 2025-02-28

Electroacupuncture has been shown to improve cerebral blood flow in animal models of stroke. However, it is unclear whether electroacupuncture alters miRNA expression the cortex. In this study, we examined changes cortical profile, and neurological function induced by a rat model was performed at Renzhong (GV26) Neiguan (PC6), with frequency 2 Hz, continuous wave, current intensity 3.0 mA, stimulation time 1 minute. increased alleviated impairment rats. microarray profiling revealed that...

10.4103/1673-5374.197135 article EN cc-by-nc-sa Neural Regeneration Research 2016-01-01

Acupuncture dose–effect relationship is the essential feature of acupuncture and key factor acupuncture's therapeutic effect. It a comprehensive category, including needle direction, strength, depth, selection specific techniques, length time between treatment sessions, retention time, frequency treatment, all which play decisive role in curative effect prognosis diseases[1]. 1 Historical evolution dose A lot diseases syndromes Inner Canon Huangdi (Huáng Dì Nèi Jīng) are mainly treated by...

10.1097/hm9.0000000000000009 article EN cc-by-nc-nd Acupuncture and Herbal Medicine 2021-09-01

Evidence from clinical reports has indicated that acupuncture a promising effect on mild cognitive impairment (MCI). However, it is still unknown by what way can modulate brain networks involving the MCI. In current study, multivariate Granger causality analysis (mGCA) was adopted to compare interregional effective connectivity of varying needling depths (deep acupuncture, DA; superficial SA) and at different states, which were MCI healthy control (HC). Results DA KI3 in showed dorsolateral...

10.1155/2013/127271 article EN Evidence-based Complementary and Alternative Medicine 2013-01-01

The root of Millettia speciosa Champ. (MSCP) is used in folk medicine and popular as a soup ingredient. composed the rhizome radix, but only radix has been food. Thus, it very important to compare chemical components antioxidant activities between radix. extracts were analyzed by UHPLC-Q-Exactive Orbitrap-MS multivariate analysis, evaluated 2,20-azinobis (3-ethylbenzothiazo-line-6-sulfonic acid) diammonium salt (ABTS) 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assays. Ninety-one...

10.3390/molecules27217398 article EN cc-by Molecules 2022-10-31

Tongguan Liqiao acupuncture therapy has been shown to effectively treat dysphagia after stroke-based pseudobulbar paralysis. We presumed that this would be effective for bulbar paralysis in patients with brainstem infarction. Sixty-four following infarction were recruited and divided into a medulla oblongata group (n = 22), midbrain pons 16), multiple cerebral 26) according their magnetic resonance imaging results. All received 28 days. The main acupoints Neiguan (PC6), Renzhong (DU26),...

10.4103/1673-5374.177737 article EN cc-by-nc-sa Neural Regeneration Research 2016-01-01

Xingnao Kaiqiao (XNKQ) acupuncture is an technique used for stroke patients. In 24 healthy volunteers, we applied this complex intervention, which consists of a manual needle-stimulation on five points (DU26 unilaterally, PC6, and SP6 bilaterally). XNKQ was compared to three control conditions: (1) insertion needles the without stimulation, (2) nearby non-acupuncture points, (3) stimulation. within-subject design, investigated functional connectivity changes in resting-state magnetic...

10.3389/fnins.2019.00147 article EN cc-by Frontiers in Neuroscience 2019-03-11

170 SD rats were randomly divided to five groups. Rats in model group, no-acupuncture and acupuncture group subjected MCAO surgery. Acupuncture received 3 consecutive treatments at a parameter that deep 2 mm towards apex nasi thrust/lifted times per second for 1 minute, while no-intervention control Serious neural functional damage sharp decrease of cerebral blood flow, obvious infarction volume, increased nestin mRNA expression, immunopositive cells population (nestin(+), BrdU(+)...

10.1155/2014/962343 article EN cc-by Evidence-based Complementary and Alternative Medicine 2014-01-01

Acupuncture is a complementary and nonpharmacological intervention that can be effective for the management of chronic pain in addition to or instead medication. Various animal models neuropathic pain, inflammatory cancer-related visceral already exist acupuncture research. We used newly validated human model examined whether influence experimentally induced dental pain. For this study, we compared impact manual (real acupuncture), stimulation needle inserted at nonacupuncture points (sham...

10.1016/j.jpain.2019.08.013 article EN publisher-specific-oa Journal of Pain 2019-09-12

In some previous studies, transcutaneous electrical nerve stimulation (TENS) to the back was shown improve non-verbal short-term and long-term memory as well verbal fluency in patients early stage of Alzheimer's disease (AD). Moreover, patients' physical, social affective functions were also improved. this study, effects TENS applied face studied with mild severe AD. Fourteen probable AD used subjects. To evaluate treatment, subjects underwent two kinds neuropsychological tests a pupillary...

10.1163/156855701321138905 article EN Frontiers of Medical & Biological Engineering 2001-01-01

To observe the effects of different acupuncture manipulations on blood pressure and target organ damage in spontaneously hypertensive rats (SHRs), this study used reinforcing twirling method (1.5–2-mm depth; rotating needle clockwise for 360° then counter 360°, with thumb moving heavily forward gently backward, 60 times per minute 1 minute, retaining 9 minutes), reducing backward forward, depth 10 minutes). Bilateral Taichong (LR3) was treated by using manual stimulation. Reinforcing...

10.4103/1673-5374.206648 article EN cc-by-nc-sa Neural Regeneration Research 2017-01-01
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