A5041577319- Occupational Health and Safety Research
- Cardiac Fibrosis and Remodeling
- Musculoskeletal pain and rehabilitation
- Blood Pressure and Hypertension Studies
- Air Quality and Health Impacts
- Cardiovascular Function and Risk Factors
- Ergonomics and Musculoskeletal Disorders
- Health, Medicine and Society
- Occupational exposure and asthma
- Hemodynamic Monitoring and Therapy
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Signaling Pathways in Disease
- Quality and Safety in Healthcare
- Cardiovascular Syncope and Autonomic Disorders
- Medication Adherence and Compliance
- Risk and Safety Analysis
- Chemical Safety and Risk Management
- Ethics in Clinical Research
- Heart Rate Variability and Autonomic Control
- Pregnancy-related medical research
- Healthcare Systems and Practices
- Historical and Scientific Studies
- Protease and Inhibitor Mechanisms
- Patient-Provider Communication in Healthcare
- Noise Effects and Management
Institut National de Recherche et de Sécurité
2013-2025
Auvergne-Rhone-Alpes Entreprises
2017
Institut de Veille Sanitaire
2011
Inserm
2002-2010
Hôpital Jeanne d'Arc
2004-2010
Université de Lorraine
2005-2007
Centre d’Investigation Clinique Innovation Technologique de Nancy
2005-2007
Université Grenoble Alpes
2005
Hôpital Lapeyronie
1998
Centre Hospitalier Universitaire de Montpellier
1994-1997
OBJECTIVE To evaluate the relative value of plasma glucose (PG) at different time points in assessing control type 2 diabetic patients. RESEARCH DESIGN AND METHODS Glycemic profiles, i.e., PG prebreakfast (8:00 A.M.), prelunch (11:00 postlunch (2:00 P.M.), and extended (5:00 P.M.) times over same day, were obtained 66 patients on an ambulatory basis. The compared with a measurement HbA1c made reference laboratory. RESULTS Extended was lower than (104 ± 21 vs. 133 35 mg/dl, P < 0.02)...
Resorcinol is a widespread substance used in large variety of manufacturing industries, including cosmetics, with endocrine-disrupting activity on the thyroid function. The aim present study was to develop and validate sensitive, selective robust method quantify resorcinol urine thereby assess hairdressers' occupational exposure. As mainly excreted as glucuronide or sulfate forms, first step consisted hydrolyzing samples β-glucuronidase-arylsulfatase enzyme for 16 h. Then, after cleaning...
Ventricular arrhythmia is the main cause of sudden cardiac death. Intracardiac strain, myocardial and extracellular matrix remodelling, subsequent fibrosis are involved in pathogenesis. The present study investigates relationship between [procollagen type I aminoterminal peptide (PINP), procollagen III (PIIINP), TIMP1, membrane metalloproteinase I], pressure overload [brain natriuretic (BNP)] inflammation [high sensitivity (hs)-C-reactive protein] serum markers, incidence ventricular...
<sec> <title>BACKGROUND</title> Cosmetic legislation is ensuring the safety of cosmetics for consumers but not professional use. All around world, hairdressing sector constitutes a major occupational group including about 90% women continuously exposed to numerous chemical composing products, among them endocrine disrupting compounds such as resorcinol, parabens, phtalates, UV filters. The thyroid-disrupting chemicals are substances concern incidence thyroid dysfunction has increased...
Recent global economic difficulties have widened social inequalities, but their impact on pregnant workers is not known.To investigate the association between deprivation, exposure to occupational hazards and adverse perinatal outcomes in workers.A cross-sectional study performed 2014 French health services. Eligible were women who had worked during pregnancy a medical visit by physicians (OHPs) after delivery at time of returning work. Deprivation was measured using EPICES scale (Evaluation...
Concern has been raised about the potential impact of nanomaterials exposure on human health, and France decided to implement a timely epidemiological surveillance tool workers likely be exposed engineered that could accompany development nanotechnologies.A comprehensive review toxicological literature conducted together with an exploratory study among French companies producing or handling nanoobjects.A double system is proposed consisting prospective cohort survey repeated cross-sectional...
The relatively recent development of industries working with nanomaterials has created challenges for exposure assessment. In this article, we propose a simple approach to assessing nanomaterial exposures the purposes epidemiological studies workers in these industries. This method consists an onsite industrial hygiene visit facilities carried out individually and description workstations where nano-objects their agglomerates aggregates (NOAA) are present using standardized tool, Onsite...
Abstract The content of informed consent documents (ICD) is a crucial element in the process providing information to participants biomedical research. Clear comprehension information, i.e. ability understand its meaning and consequences, utmost importance. objective this study was describe different steps French adaptation preliminary validation Qualité de Compréhension des Formulaires d'information et consentement (QCFic) questionnaire ( http://www.lyon.inserm.fr/cic‐grenoble ) based on...
Information is the keystone to participation of subjects in biomedical research. Clear comprehension informed consent documents (ICDs) primordial and a necessary requirement that they are readable. While submission protocol French 'Comités de Protection des Personnes' (CPP) mandatory step with regard legislation on research, no published data available concerning its influence ICDs readability. The aim our study was determine impact CPP readability ICDs, using lexico-syntactic indexes from...
The prognosis of cholesterol embolism is often poor, and no treatment presently available. We report the use a stable prostacyclin analogue in treating diabetic patient with arteriopathy. As sole therapy, it improved cutaneous manifestations pain, parallel an increased transcutaneous oxymetry. think that analogues are novel candidates for embolism. © 1998 John Wiley & Sons, Ltd.
Abstract Amlodipine and valsartan are once‐daily antihypertensive agents. To date, no comparison between these agents given as monotherapies was reported. This study aimed to evaluate the therapeutic coverage safety of amlodipine in mild‐to‐moderate hypertensive patients. Multicenter, double‐blind, randomized, comparative study. After a 4‐week placebo wash‐out period, 246 outpatients with office diastolic blood pressure 95 ≤ DBP ≤110 mmHg systolic (SBP) < 180 mmHg, addition mean daytime...
The French national epidemiological surveillance program EpiNano aims at surveying mid- and long-term health effects possibly related with occupational exposure to either carbon nanotubes or titanium dioxide nanoparticles (TiO2). is limited workers potentially exposed these nanomaterials including their aggregates agglomerates. In order identify those during the in-field industrial hygiene visits, a standardized non-instrumental method necessary especially for epidemiologists physicians...
<h3>Rationale</h3> Engineered nanomaterials (ENMs) induce groundbreaking impacts by endowing unique properties to materials. However, uncertainties remain on their biological aftereffects. Entrusted health and labour ministries, the French Public Health Institute launched since 2014 EpiNano epidemiological surveillance program of workers potentially exposed ENMs. The 2016–2020 national occupational (OH) action plan inscribed ENMs topic as priority, with an enlargement construction...