A5080032095- Acupuncture Treatment Research Studies
- Neurological Disease Mechanisms and Treatments
- Cancer-related molecular mechanisms research
- Endometrial and Cervical Cancer Treatments
- Cancer, Lipids, and Metabolism
- Renal cell carcinoma treatment
- Healthcare and Venom Research
- Prostate Cancer Treatment and Research
- Renal and related cancers
- Cervical Cancer and HPV Research
- Metastasis and carcinoma case studies
- Nonlinear Waves and Solitons
- Cancer-related Molecular Pathways
- Cardiac Arrest and Resuscitation
- Inflammatory Biomarkers in Disease Prognosis
- Traditional Chinese Medicine Studies
- Bladder and Urothelial Cancer Treatments
- Cancer Diagnosis and Treatment
- Chromatin Remodeling and Cancer
- Vascular Malformations and Hemangiomas
- Barrier Structure and Function Studies
- Uterine Myomas and Treatments
- Tuberous Sclerosis Complex Research
- Cancer Mechanisms and Therapy
- Mechanisms of cancer metastasis
University of Electronic Science and Technology of China
2021-2025
Linyi People's Hospital
2023-2025
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2019-2024
Guangzhou University of Chinese Medicine
2024
Linyi University
2023
Weifang Medical University
2023
Chinese Academy of Sciences
2022
Sichuan University
2012-2022
State Key Laboratory of Biotherapy
2012-2022
Gansu University of Traditional Chinese Medicine
2016-2022
Emerging studies show that long noncoding RNAs (lncRNAs) play important roles in carcinogenesis and cancer progression. The lncRNA ZEB1 antisense 1 (ZEB1-AS1) derives from the promoter region of we still know little about its expressions, mechanisms.RACE was used to obtain sequence ZEB1-AS1. RNA interference decrease ZEB1-AS1 expression. Adenovirus expression vector increase CHIP RIP were detect epigenetic mechanisms by which regulated ZEB1. CCK8 assay, wound healing assay transwell measure...
Glioma is the most common primary malignant tumor of central nervous system, and due to limited effectiveness traditional single-target therapies, there an urgent need for new therapeutic targets. Centromere protein F (CENPF) belongs centromere family mainly involved in regulation cell cycle. CENPF has recently been found play a key role tumorigenesis progression, but its gliomas not well studied. The expression level clinical information were obtained by analyzing TCGA, CGGA GEO databases....
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 4-deficient non-small cell lung cancer (SMARCA4-dNSCLC) is a rare subtype NSCLC whose definitive radiographic characteristics have not yet been fully delineated. Clinically, these tumors often metastasize to distant organs and lymph nodes at an early stage, which strongly associated with poor clinical prognosis. The common metastatic sites include bone, brain, adrenal glands, liver, spleen,...
To study the distribution pattern of lymph node metastases stage IA to IIA cervical cancer and clarify individualized clinical target volume delineation regional nodes (CTVn). A total 665 cases with International Federation Gynecology Obstetrics who underwent radical hysterectomy pelvic lymphadenectomy were retrospectively reviewed. The clinicopathological factors related analyzed using logistic regression analysis. Pelvic found in 168 patients resulting a metastasis rate 25.3%. Binary...
Abstract Background The homeodomain‐containing transcription factor NANOG is overexpressed in prostate adenocarcinoma (PCa) and predicts poor prognosis. SOX family SOX9, as well the co‐activator HMGB3 of HMGB family, are also may play pivotal roles PCa. However, it unknown whether SOX9 interact with each other, or if they regulate gene transcription. Methods We identified potential responsive elements promoter, investigated regulated co‐operation by experimental analysis binding sites...
BACKGROUND The transcription factors Sp3/Sp1 are expressed in a various types of cancers and BNIP3 is overexpressed prostate cancer. Although it has been demonstrated that transcriptionally regulated by HIF-1α post-transcriptionally miR145, our previous data indicated there might be some other regulating This study conducted to investigate whether expression directly or not. MATERIALS AND METHODS Bioinformatics analysis shows promoter contains several potential binding sites. And then SP3...
Background The ERK signaling pathway is frequently deregulated in tumorigenesis, mostly by classical mechanisms such as gene mutation of its components (eg, RAS and RAF ). However, whether how multiple key are regulated microRNAs not clear. Methods We firstly predicted post‐transcriptional regulation the miR181c through bioinformatics analysis, then confirmed dual luciferase reporter assays Western blot analysis. biological effects on prostate cancer cell proliferation, apoptosis, migration,...
This study aimed to investigate the metastatic rate of circumflex iliac node distal external (CINDEIN) and its associations with clinicopathological factors in patients stage IA IIA cervical cancer determine whether dissection CINDEIN had a role surgery these patients.Six hundred thirty-three International Federation Gynecology Obstetrics who underwent radical hysterectomy pelvic lymphadenectomy were retrospectively reviewed. The distribution lymph nodes (PLNs) CINDEINs analyzed.The PLN was...
To compare the efficacy differences between manual acupuncture (MA) and electroacupuncture (EA) in treatment of hemiplegia after acute ischemic stroke.Sixty-eight patients stroke were randomized into a MA group (34 cases) an EA cases). The routine western medication bilateral Dingnieqianxiexian (MS 6) adopted two groups. needles retained for 30 min. In group, even-needling technique was used 3 times during needle retaining, 1 min each time. on basis stimulation, therapy added, with...
The SOX4 (sex‐determining region Y‐related high‐mobility‐group box transcription factor 4) gene plays critical roles in embryonic development and cell‐fate determination. Recently, overexpression has been found various tumors. However, its expression status prognostic significance astrocytoma remain unknown. In this study, diffusely infiltrating ( WHO grades II ‐IV) tissues (in comparison with pilocytic astrocytomas) was examined by immunohistochemistry, relevance prognosis analyzed. Our...
To compare the dosimetry, toxicity, and efficacy of simultaneous modulated accelerated radiotherapy (SMART) with 3-dimensional conformal (3DCRT) in cervical cancer retroperitoneal lymph node metastasis after radical hysterectomy pelvic lymphadenectomy.Total 32 patients who underwent SMART were retrospectively evaluated. Daily fractions 2.2 to 2.4 Gy 1.8 2 prescribed delivered gross tumor volume clinical target a total dose 63.8 52.2 Gy, respectively. A 3DCRT plan was designed for group...
Uterine leiomyomas are the most common gynecological tumors in women of child-bearing age and premenopausal women, while benign metastasizing heart rare.We report a rare case leiomyoma 54-year-old woman 10 years after uterine was discovered during hysterectomy. Echocardiography, cardiac plain scan enhanced MRI at presentation showed soft tissue signal mass right ventricle. A large attached to chordae tricuspid valve later shown be histopathologically consistent with successfully resected...