A5102883517- Cancer, Hypoxia, and Metabolism
- RNA modifications and cancer
- Cancer Treatment and Pharmacology
- Colorectal Cancer Treatments and Studies
- Esophageal Cancer Research and Treatment
- Endometrial and Cervical Cancer Treatments
- Social Media in Health Education
- Cancer Cells and Metastasis
- MicroRNA in disease regulation
- Intraperitoneal and Appendiceal Malignancies
- Helicobacter pylori-related gastroenterology studies
- Endoplasmic Reticulum Stress and Disease
- Animal Genetics and Reproduction
- Cancer, Lipids, and Metabolism
- Ovarian cancer diagnosis and treatment
- Anesthesia and Neurotoxicity Research
- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- Management of metastatic bone disease
- Health Literacy and Information Accessibility
- Alcohol Consumption and Health Effects
- Family Support in Illness
- Vitamin D Research Studies
- Advanced Radiotherapy Techniques
- Cancer survivorship and care
Shandong First Medical University
2008-2024
Shandong Tumor Hospital
2012-2024
Shandong University
2019
Hypoxia promotes tumor invasion and metastasis via multiple mechanisms, including epithelial-mesenchymal transition (EMT). Twist, an EMT regulator, has been disclosed to associate with as well poor prognosis of many malignancies. However, it remains undefined whether Twist is involved in hypoxic non-small cell lung cancer (NSCLC). In this study, protein levels hypoxia-inducible factor-1α (HIF-1α), markers (E-cadherin vimentin) were examined by immunohistochemistry 76 tissues from NSCLC...
Ovarian cancer is one of the leading causes female death worldwide, with a poor prognosis advanced patients. Sevoflurane, volatile anesthetic commonly used in clinical operations, has been reported to have anti-cancer activity against some tumors. In present study, we aimed investigate effects sevoflurane on progression ovarian and its potential mechanism.The cell viability, proliferation, migration, invasion, cycle, apoptosis were determined by functional experiments vitro. Gelatin...
: Esophageal squamous cell carcinoma (ESCC) has been having a high mortality rate in China. Most patients are diagnosed advanced stages, leading to the poor prognosis and low 5-year survival rate. Detection of precancerous lesions or early cancers is key improving this situation. Although previous studies have identified some risk factors for ESCC, they rarely paid attention premalignant esophageal lesions. We thus initiated population-based screening study aiming assess associated with...
Abstract Health literacy is closely related to the incidence of major chronic diseases and its behaviors such as cancer-related behaviors. This study explored how cancer health level affects About one two villages from six cities Shandong province were selected sample areas. Professionals conducted face-to-face interviews with participants. Finally, 1200 residents completed 1085 effective questionnaires. Data analysed a cross-sectional survey in 2019, which included cities/counties province,...
The purpose of this study is to evaluate the influence germline polymorphisms cytochrome P450 (CYP450) on objective response, progression-free survival (PFS) and overall suruvival (OS) in metastatic colorectal cancer (mCRC) receiving combination chemotherapy irinotecan, 5-fluorouracil, leucovorin (FOLFIRI). All SNPs CYP450, whose minor allele frequency were more than 10 %, genotyped 82 patients with mCRC who received first-line FOLFIRI regimen. χ (2) test or Fisher's exact was used assess...
To compare the dosimetry, toxicity, and efficacy of simultaneous modulated accelerated radiotherapy (SMART) with 3-dimensional conformal (3DCRT) in cervical cancer retroperitoneal lymph node metastasis after radical hysterectomy pelvic lymphadenectomy.Total 32 patients who underwent SMART were retrospectively evaluated. Daily fractions 2.2 to 2.4 Gy 1.8 2 prescribed delivered gross tumor volume clinical target a total dose 63.8 52.2 Gy, respectively. A 3DCRT plan was designed for group...