- Cancer, Stress, Anesthesia, and Immune Response
- Cancer, Hypoxia, and Metabolism
- Rabbits: Nutrition, Reproduction, Health
- Cancer therapeutics and mechanisms
- Reproductive Biology and Fertility
- Anesthesia and Neurotoxicity Research
- Milk Quality and Mastitis in Dairy Cows
- Adrenal and Paraganglionic Tumors
- Cell Adhesion Molecules Research
- Plant-based Medicinal Research
- Eicosanoids and Hypertension Pharmacology
- Receptor Mechanisms and Signaling
- Galectins and Cancer Biology
- Sperm and Testicular Function
- Cell death mechanisms and regulation
- Animal Genetics and Reproduction
- Nitric Oxide and Endothelin Effects
- Reproductive System and Pregnancy
- Ubiquitin and proteasome pathways
- Agriculture, Soil, Plant Science
- Synthesis of heterocyclic compounds
Shandong First Medical University
2013-2020
Shandong Tumor Hospital
2013-2020
Academy of Medical Sciences
2020
Northeast Agricultural University
2020
Ovarian cancer is one of the leading causes female death worldwide, with a poor prognosis advanced patients. Sevoflurane, volatile anesthetic commonly used in clinical operations, has been reported to have anti-cancer activity against some tumors. In present study, we aimed investigate effects sevoflurane on progression ovarian and its potential mechanism.The cell viability, proliferation, migration, invasion, cycle, apoptosis were determined by functional experiments vitro. Gelatin...
Identifying novel tumor biomarkers to develop more effective diagnostic and therapeutic strategies for patients with ACC is urgently needed. The aim of the study was compare proteomic profiles between adrenocortical carcinomas (ACC) normal tissues in order identify potential ACC. protein samples from 12 their paired adjacent were profiled two-dimensional electrophoresis; differentially expressed proteins identified by mass spectrometry. Expression patterns three differently calreticulin,...
Abstract Background : Previous studies have shown that some anesthesia drugs can inhibit tumor growth and metastasis. As a clinical anesthetic drug, dezocine has been reported to play an important role in immune function. However, the effects of on ovarian cancer cell metastasis are not fully understood. Results In this study, we found dose-dependently inhibited viability ES-2 SKOV3 cells. Dezocine suppressed migration invasion abilities cells promoted apoptosis. Moreover, Akt/mTOR signaling...
Abstract Background Previous studies have shown that some anesthesia drugs can inhibit tumor growth and metastasis. As a clinical anesthetic drug, dezocine has been reported to play an important role in immune function. However, the effects of on ovarian cancer cell metastasis are not fully understood. Results In this study, we found dose-dependently inhibited viability ES-2 SKOV3 cells. Dezocine suppressed migration invasion abilities cells, promoted apoptosis. Moreover, Akt/mTOR signaling...