Yingxiang Lin
A5086886186- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Respiratory Support and Mechanisms
- Pediatric health and respiratory diseases
- Air Quality and Health Impacts
- Neonatal Respiratory Health Research
- Oral microbiology and periodontitis research
- Pleural and Pulmonary Diseases
- Climate Change and Health Impacts
- Cystic Fibrosis Research Advances
- Respiratory and Cough-Related Research
- Dental Health and Care Utilization
- HIV/AIDS oral health manifestations
- Medical Imaging and Pathology Studies
- Smoking Behavior and Cessation
- Traditional Chinese Medicine Studies
- Urban Green Space and Health
- Genetics and Physical Performance
- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Injury Epidemiology and Prevention
- Cardiac Health and Mental Health
- Acupuncture Treatment Research Studies
- Urban Heat Island Mitigation
- Air Quality Monitoring and Forecasting
Beijing Chao-Yang Hospital
2015-2024
Capital Medical University
2014-2024
Beijing Institute of Neurosurgery
2015-2024
Woolcock Institute of Medical Research
2022
Shanghai Pulmonary Hospital
2022
Beijing Chaoyang Emergency Medical Center
2020
Yang Hospital
2020
Capital University
2013-2019
Depression and anxiety are significant comorbid potentially modifiable conditions in chronic obstructive pulmonary disease (COPD), but their effects on exacerbations not clear.To investigate the independent effect of depression risk COPD hospitalizations.A multicenter prospective cohort study 491 patients with stable China. Multivariate Poisson linear regression analyses were used, respectively, to estimate adjusted incidence rate ratios (IRRs) duration events.Depression measured using...
Patients with mild or moderate chronic obstructive pulmonary disease (COPD) rarely receive medications, because they have few symptoms. We hypothesized that long-term use of tiotropium would improve lung function and ameliorate the decline in patients COPD.
BackgroundThe prevalence, epidemiological and clinical heterogeneities, impact profiles of individuals with preserved ratio impaired spirometry (PRISm), pre-COPD, young COPD, mild COPD in general Chinese population were not known yet.MethodsData obtained from the China Pulmonary Health study (2012–2015), a nationally representative cross-sectional survey that recruited 50,991 adults aged 20 years or older. Definitions four early disease status consistent latest publications Global Initiative...
The associations of long-term exposure to various constituents fine particulate matter (≤2.5 μm in aerodynamic diameter, PM2.5) air pollution with lung function were not clearly elucidated developing countries. aim was evaluate the main PM2.5 China. This is a nationwide, cross-sectional analysis among 50,991 study participants from China Pulmonary Health study. Multivariable linear regression models used obtain differences forced expiratory volume 1 s (FEV1), vital capacity (FVC), FEV1/FVC,...
Rationale: It remains unknown whether long-term ozone exposure can impair lung function. Objectives: To investigate the associations between and adult function in China. Methods: Lung results diagnosis of small airway dysfunction (SAD) were collected from a cross-sectional study, China Pulmonary Health Study (N = 50,991). We used multivariable linear logistic regression models to examine with parameters SAD, respectively, adjusting for demographic characteristics, individual risk factors,...
Background and objectives: Chronic obstructive pulmonary disease (COPD) is responsible for significant morbidity mortality worldwide. We evaluated the characteristics of stable COPD patients in pulmonology clinics seven Asian cities also whether exposure to biomass fuels dusty jobs were related respiratory symptoms, airflow limitation, quality life patients. Methods: This cross-sectional observational study recruited 922 from Asia. The underwent spirometry administered questionnaires about...
Purpose: Peripheral blood eosinophilic counts are susceptible to many factors and have variability over time. There limited studies on association of eosinophilia with long-term mortality chronic obstructive pulmonary disease (COPD) patients these results remain controversial. Our aims were explore the at index hospitalization stability 5 years all-cause hospitalized for acute exacerbation COPD (AECOPD). Patients Methods: Eight hundred twenty-nine AECOPD between 2013 2014 included in this...
There is insufficient information about the prevalence and risk factors of gastroesophageal reflux disease (GERD) in Chinese adult population. We aimed to assess identify GERD China.We collected data from a nationally representative sample (50,991 subjects) adults large nation-wide cross-sectional survey. was diagnosed by standardized Chinese-language questionnaire with score ≥ 8. The demographic characteristics, comorbidities periodontal all participants were...
Chronic cough is a common complaint, but there are no population-based data on its burden in China. We determined the prevalence of chronic and impact health status adults stratified by sex, age diagnosis COPD or presence small airway dysfunction (SAD).A representative sample 57 779 Chinese aged 20 years older was recruited pulmonary function test measured. defined as lasting for >3 months each year. Quality life assessed 12-item Short Form Health Survey (SF-12), self-reported history...
Recent studies have shown that polymorphisms of the angiotensin-converting enzyme (ACE) gene are closely associated with pulmonary disorders. The ACE is involved in regulation inflammatory reactions to lung injury, respiratory drive, erythropoiesis and tissue oxygenation. hypothesis for this study was may be ventilatory response exercise aerobic work efficiency skeletal muscle patients COPD.Sixty-one Chinese Han COPD 57 healthy control subjects performed incremental cardiopulmonary testing...
Abstract Aim To assess the status of periodontal health knowledge, attitudes and practices ( KAP ) among Chinese adults. Materials Methods A cross‐sectional study was conducted in a nationally representative sample adults N = 50,991) aged 20 years or older from ten provinces, autonomous regions, municipalities. Percentages with correct positive attitudes, were estimated. Multiple logistic regression analyses used to examine related factors. Results Less than 20% knowledgeable about disease....
Purpose: Anxiety and depression are often underdiagnosed affect the prognosis of patients with chronic obstructive pulmonary disease (COPD). We analyzed data from China Pulmonary Health (CPH) study to assess prevalence anxiety in COPD their relationship severity. Patients Methods: A total 57,779 subjects aged 20 years or older were recruited CPH study. All participants assessed using a standard questionnaire underwent function tests before after use bronchodilator local health centers. The...
Background: SARS-CoV-2 tends to cause more severe disease in patients with COPD once they are infected. We aimed investigate the rates of influenza, pneumococcal and COVID-19 vaccination uptake determine whether pandemic widespread against had any impact on intention accept influenza vaccines these patients. Methods: conducted a multi-center cross-sectional survey seven tertiary hospitals Beijing consecutively recruited outpatients from June 1st July 30th, 2021. The included patient's...
Background Maternal smoking during pregnancy (MSDP) is a known risk factor for offspring developing chronic obstructive pulmonary disease (COPD), but the underlying mechanism remains unclear. Objective This study aimed to explore whether increased COPD associated with MSDP could be attributed tobacco dependence (TD). Methods case-control used data from nationwide cross-sectional China Pulmonary Health study, controls matched age, sex, and status. TD was defined as within 30 minutes of...
Background Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide has been the leading death in China. Patients with COPD have significant decrements their healthrelated quality life (HRQL). It necessary to identify factors involved worsening HRQL order improve patients. However, evidence from longitudinal studies limited. The aim study was evaluate determinants deterioration patients COPD. Methods At baseline, total 491 stable received...
Currently, the majority of genetic association studies on chronic obstructive pulmonary disease (COPD) risk focused identifying individual effects single nucleotide polymorphisms (SNPs) as well their interaction disease. However, conventional often use binary status primary phenotype, but for COPD, many quantitative traits have potential correlation with and closely reflect pathological changes. Here, we genotyped 44 SNPs from four genes (EPHX1, GSTP1, SERPINE2, TGFB1) in 310 patients 203...
Patients with features of both asthma and chronic obstructive pulmonary disease (COPD) are seen commonly in the clinic but less is known general population. We investigated prevalence heterogeneity COPD concomitant Chinese adult population.COPD was defined as post-bronchodilator ratio forced expiratory volume 1s (FEV1) to vital capacity than lower limits normal. either diagnosed by self-reported physician-diagnosis or presence current wheeze, high bronchodilator response (HBR) an increase...
Corticosteroid is one of the most commonly used medications in patients with acute exacerbations chronic obstructive pulmonary disease (AECOPD). The increasing understanding these side-effects systematic corticosteroids and their better response to treatment among COPD higher blood eosinophil counts has led an interest a more targeted approach corticosteroid treatment. However, there lack evidence from high-quality randomised controlled trial (RCT) studies about whether initial should be...