Lirong Liang

ORCID: 0000-0002-0343-992X
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About
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Research Areas
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Venous Thromboembolism Diagnosis and Management
  • Asthma and respiratory diseases
  • Air Quality and Health Impacts
  • Intensive Care Unit Cognitive Disorders
  • Anesthesia and Neurotoxicity Research
  • Anesthesia and Sedative Agents
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Respiratory and Cough-Related Research
  • Cardiovascular Health and Disease Prevention
  • Smoking Behavior and Cessation
  • Climate Change and Health Impacts
  • Influenza Virus Research Studies
  • Neonatal Respiratory Health Research
  • Respiratory viral infections research
  • Atrial Fibrillation Management and Outcomes
  • Pulmonary Hypertension Research and Treatments
  • Pediatric health and respiratory diseases
  • Air Quality Monitoring and Forecasting
  • Viral gastroenteritis research and epidemiology
  • Diagnosis and Treatment of Venous Diseases
  • Occupational and environmental lung diseases
  • Respiratory Support and Mechanisms
  • Lymphoma Diagnosis and Treatment
  • Acute Myocardial Infarction Research

Beijing Chao-Yang Hospital
2016-2025

Capital Medical University
2016-2025

Air Force Medical University
2015-2024

Yan'an Hospital Affiliated To Kunming Medical University
2024

Kunming Medical University
2024

Creative Commons
2023

Second Affiliated Hospital of Nanchang University
2023

Nanchang University
2023

Guangzhou Xinhua University
2023

Haikou City People's Hospital
2023

Evidence of whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes disease 2019 (COVID-19), can be transmitted as an aerosol (ie, airborne) has substantial public health implications.To investigate potential transmission routes SARS-CoV-2 infection with epidemiologic evidence from a COVID-19 outbreak.This cohort study examined community outbreak in Zhejiang province. On January 19, 2020, 128 individuals took buses (60 [46.9%] bus 1 and 68 [53.1%] 2) on...

10.1001/jamainternmed.2020.5225 article EN JAMA Internal Medicine 2020-09-01

An association between sleep duration and the trajectory of cognitive decline has not been conclusively demonstrated.

10.1001/jamanetworkopen.2020.13573 article EN cc-by-nc-nd JAMA Network Open 2020-09-21

Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies. Neovascularization during tumorigenesis supplies oxygen and nutrients to proliferative tumor cells, serves as a conduit for migration. Targeting oncogenes involved in angiogenesis needed treat organ-confined locally advanced ESCC. Although phospholipase C epsilon-1 (PLCE1) gene was originally identified susceptibility ESCC, how PLCE1 ESCC unclear. Matrix-assisted laser desorption ionization time-of-flight mass...

10.1186/s12943-018-0930-x article EN cc-by Molecular Cancer 2019-01-04

BackgroundAir pollution in Beijing has been improving through implementation of the Air Pollution Prevention and Control Action Plan (2013–17), but its implications for respiratory morbidity have not directly investigated. We aimed to assess potential effects air-quality improvements on health by investigating number cases acute exacerbations chronic obstructive pulmonary disease (COPD) advanced air each year.MethodsDaily city-wide concentrations PM10, PM2·5, PMcoarse (particulate matter...

10.1016/s2542-5196(19)30085-3 article EN cc-by The Lancet Planetary Health 2019-06-01

<h3>Importance</h3> Studies examining the association of low to moderate drinking with various cognitive functions have yielded mixed findings. <h3>Objective</h3> To investigate whether associations exist between alcohol and function trajectories or rates change in from middle age older among US adults. <h3>Design, Setting, Participants</h3> A prospective cohort study participants drawn Health Retirement Study (HRS), a nationally representative sample adults, mean (SD) follow-up 9.1 (3.1)...

10.1001/jamanetworkopen.2020.7922 article EN cc-by-nc-nd JAMA Network Open 2020-06-29

Background There has not been sufficient evidence to support the Asians being less susceptible pulmonary embolism (PE) than other ethnicities, because prevalence of PE/deep venous thrombosis (DVT) in different racial and ethnic groups carefully studied until recently except Caucasians. To test hypothesis that Chinese population a lower risk for PE, this study comprehensively assessed hospital-based incidence case fatality rates PE during 1997–2008 China. Methods A registration patients with...

10.1371/journal.pone.0026861 article EN cc-by PLoS ONE 2011-11-01

Early identification and treatment of chronic thromboembolic pulmonary hypertension (CTEPH) are critical to prevent disease progression. We determined the incidence risk factors for CTEPH in patients with a first episode acute embolism (PE).In this study, consecutive first-episode PE were followed ≤5 years. Pulmonary (PH) was screened by echocardiography. Suspected cases evaluated right heart catheterization (RHC) angiography (PA). If invasive procedures not permitted, PH diagnosed systolic...

10.3978/j.issn.2072-1439.2015.11.43 article EN PubMed 2015-11-01

Background There is limited data on the clinical outcome of patients with pandemic H1N1 (pH1N1) pneumonia who received oseltamivir treatment, especially when treatment was administered more than 48 hours after symptom onset. Methods During in 2009, a cohort pH1N1 influenza built China, and their information collected systematically, analyzed Cox models. Results 920 adults 541 children didn't receive corticosteroids were analyzed. In-hospital mortality higher did not antiviral therapy (18.2%)...

10.1371/journal.pone.0029652 article EN cc-by PLoS ONE 2012-01-20

Preclinical data suggest that oncogene (EGFR and KRAS) events regulate tumor procoagulant activity. However, few studies have prospectively investigated the clinical relevance between presence of EGFR or KRAS mutations occurrence venous thromboembolism(VTE) in patients with non-small cell lung cancer (NSCLC). A total 605 Chinese newly diagnosed NSCLC were included followed for a maximum period 4.5 years. determined by amplification refractory mutation system polymerase chain reaction method...

10.1186/s12931-018-0791-2 article EN cc-by Respiratory Research 2018-05-09

Rationale: It remains unknown whether long-term ozone exposure can impair lung function. Objectives: To investigate the associations between and adult function in China. Methods: Lung results diagnosis of small airway dysfunction (SAD) were collected from a cross-sectional study, China Pulmonary Health Study (N = 50,991). We used multivariable linear logistic regression models to examine with parameters SAD, respectively, adjusting for demographic characteristics, individual risk factors,...

10.1164/rccm.202107-1599oc article EN American Journal of Respiratory and Critical Care Medicine 2021-11-23

Proteins have tremendous potential for vaccine development and disease treatment, but multiple extracellular intracellular biological barriers must be overcome before they can exert specific functions in the target tissue. The use of polymers as carriers would greatly improve their bioavailability therapeutic efficiency. Nevertheless, effective protein packaging cell membrane penetration without causing cytotoxicity is particularly challenging, due largely to simultaneous distribution...

10.1021/acsmacrolett.3c00155 article EN ACS Macro Letters 2023-04-24

BackgroundData on symptoms and radiographic changes in patients with pandemic 2009 influenza A(H1N1) (A[H1N1]) pneumonia during convalescence have not been reported.MethodsDuring October 26, 2009, January 23, 2010, adult laboratory-confirmed or clinically suspected infections were observed for clinical characteristics, high-resolution chest CT scan, lung function test acute 3-month convalescent phases.ResultsOf the 65 case subjects, median age was 41 (interquartile range [IQR], 28-57) years,...

10.1378/chest.10-1036 article EN other-oa CHEST Journal 2010-09-24

The aetiology and pathogenesis of interstitial lung disease (ILD) ILD combined with cancer (ILD-CA) are unclear. We aim to investigate serum tumour marker (STM) levels explore their predictive diagnostic value in ILD.Fifty-eight patients ILD-CA, 632 only 628 acute respiratory illness were studied. Serum carcinoembryonic antigen (CEA), carbohydrate 19-9 (CA19-9), CA125 neuron-specific enolase (NSE) measured.All STM elevated ILD-CA compared group (P < 0.01). CEA significantly higher than...

10.1111/resp.12317 article EN Respirology 2014-06-05

Sevoflurane (Sev) is one of the most widely used pediatric anesthetics. The major concern neonatal repeated application Sev its potential long-term impairment cognition and learning/memory, for which there still lacks effective treatment. At cellular level, exerts toxic effects in multiple aspects, making it difficult interference. Melatonin a pineal hormone regulated by feedbacks to biological rhythm at physiological condition. Recent studies have revealed significant neuroprotective...

10.1111/jpi.12771 article EN Journal of Pineal Research 2021-09-29

Continuous aluminum oxide-mullite-hafnium oxide (AMH) composite ceramic fibers were obtained by melt-spinning and calcination from polymer precursor that synthesized hydrolysis of the isopropoxide, dimethoxydimethylsilane hafnium alkoxide. Due to fine diameter 8–9 µm, small grain size less than 50 nm crystal texture, highest tensile strength AMH was 2.01 GPa. And presented good thermal stability. The retention 75.48% 71.49% after heat treatment at 1100 °C 1200 for 0.5 h respectively, 61.57%...

10.1016/j.jeurceramsoc.2022.05.047 article EN cc-by-nc-nd Journal of the European Ceramic Society 2022-05-24
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