- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- MRI in cancer diagnosis
- RNA Research and Splicing
- Parasitic infections in humans and animals
- Digital Radiography and Breast Imaging
- AI in cancer detection
- Parasites and Host Interactions
- Diverse Approaches in Healthcare and Education Studies
- Lymphoma Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
- Digital Communication and Language
- Colorectal Cancer Surgical Treatments
- Tendon Structure and Treatment
- Endometriosis Research and Treatment
- Nuclear Structure and Function
- Bioinformatics and Genomic Networks
- Consumer Perception and Purchasing Behavior
- Potassium and Related Disorders
- Ion Transport and Channel Regulation
- Cancer Cells and Metastasis
- Technology and Data Analysis
- Monoclonal and Polyclonal Antibodies Research
- Single-cell and spatial transcriptomics
Dong-A University
2025
Seoul Metropolitan Government
2018-2023
Seoul National University
2017-2023
Boramae Medical Center
2017-2023
Seoul National University Hospital
2019
Advisory Board Company (United States)
2018
Daejeon St. Mary's Hospital
2017
Catholic University of Korea
2017
National Research Foundation of Korea
2017
Hankuk University of Foreign Studies
2017
To evaluate the value of computer-aided diagnosis (CAD) program applied to diagnostic breast ultrasonography (US) based on operator experience.US images 100 masses from 91 women over 2 months (from May June 2015) were collected and retrospectively analyzed. Three less experienced imaging radiologists analyzed US features without with CAD according Breast Imaging Reporting Data System (BI-RADS) lexicon categories. We then compared performance between interobserver agreement among...
We investigated B-cell lymphoma 2 (BCL2) regulation across DNA, RNA, protein, and methylation status according to molecular subtype of breast cancer using The Cancer Genome Atlas (TCGA) database.We analyzed clinical biological data on 1,096 cancers from the TCGA database. Biological included reverse phase protein array (RPPA), mRNA sequencing (mRNA-seq), microarray, methylation, copy number alteration linear, nonlinear, mutation data.The luminal A B subtypes showed upregulated expression...
In this study, we investigated the prognostic implications of focal breast edema on preoperative magnetic resonance imaging (MRI) in patients with cancer.Data 899 cancer at a single institution were retrospectively analyzed. The divided into an edema-positive group (EPG) and edema-negative (ENG) based presence peritumoral, prepectoral, or subcutaneous edema. Two radiologists evaluated absence its subtypes MRI. Clinicopathologic characteristics survival outcomes compared between two groups...
The aim of this study was to investigate whether par-3 partitioning defective 3 homolog (C. elegans) (PARD3) single nucleotide polymorphisms (SNPs) are associated with schizophrenia. A total 204 Korean schizophrenic patients [117 male, 41.1±9.6 years (mean age ± SD); 87 female, 42.6±11.5] and 351 control subjects (170 43.8±6.6 years; 181 44.2±5.8) were enrolled. We genotyped nine SNPs the PARD3 gene [rs7075263 (intron), rs10827392 rs773970 rs2252655 rs10763984 rs3781128 (Ser889Ser),...
The aims of this study were to determine the malignancy rate probably benign lesions that show an interval change on follow-up ultrasound and evaluate differences seen imaging between malignant initially categorized as but with breast ultrasound. We retrospectively reviewed 11,323 from ultrasound-guided core-biopsies performed June 2004 December 2014 identified 289 (266 patients) (Breast Imaging Reporting Data System [BI-RADS] category 3) in previous 2 years. Malignancy rates compared...
Abstract We investigated the prognostic influences of BCL1 and BCL2 expression on disease-free survival in breast cancer patients. statuses were assessed by immunohistochemistry using tissue microarrays from 393 The Kaplan–Meier estimator log-rank test used for analyses. Cox proportional hazards model was to calculate hazard ratio (HR) 95% confidence interval (CI) revealed no impact survival. high group showed superior compared with low ( p = 0.002), especially regarding local...
We aimed to investigate the potential of preoperative mammographic breast density (MBD) as a prognostic factor in cancer. Data 969 patients with primary cancer were analyzed. defined low MBD fatty or fibroglandular breast, and high heterogeneously dense extremely respectively. The group demonstrated superior overall survival rate compared (p < 0.001). Favorable effects observed subgroups aged >50 years 0.001) positive hormone receptor (HRc) negative human epidermal growth 2 (HER2) had higher...
Hutchinson-Gilford Progeria Syndrome with G608G LMNA MutationHutchinson-Gilford progeria syndrome (HGPS) is a rare condition originally described by Hutchinson in 1886.Death result from cardiac complications the majority of cases and usually occurs at average age thirteen years.A 4-yr old boy had typical clinical findings such as short stature, craniofacial disproportion, alopecia, prominent scalp veins sclerodermatous skin.This abnormal appearance began 1 yr.On serological hormonal...
The aim of this study was to investigate the follow-up results and characteristics oval circumscribed lesions with fast initial enhancement on preoperative magnetic resonance imaging (MRI) in patients newly diagnosed breast cancer. Preoperative data from consecutive cancer between 2010 2013 were retrospectively reviewed. Only MRI reports containing, "oval shape, margin, enhancement," extracted analyzed. Follow-up clinical pathological findings evaluated. A total 430 included. Forty-eight...
BACKGROUNDParagonimiasis is a food-borne parasitic infection caused by lung flukes of the genus Paragonimus.Although most common site pleuropulmonary area, parasite can also reach other parts body on its journey from intestines to lungs, ending up in locations such as brain, abdomen, skin, and subcutaneous tissues.Ectopic paragonimiasis difficult diagnose due rarity this disease. CASE SUMMARYHere, we report rare case simultaneous breast pulmonary woman presenting painless mass nodule with...
Lymphotoxin beta receptor (LTBR) is essential for development and organization of the secondary lymphoid tissues. To investigate whether LTBR polymorphisms are associated with IgA nephropathy (IgAN) in Korean children, One hundred ninety nine patients IgAN 289 controls were recruited. Two promoter single nucleotide (SNPs) (rs3759333, -1387C/T rs3759334, -1326A/G) one coding SNP (rs2364480, Ala172Ala) gene selected genotyped by direct sequencing. For analysis data, SNPStats, SPSS 18.0,...
Sparganosis is a parasitic infestation caused by sparganum, plerocercoid tapeworm larva of the genus Spirometra. Since first case human sparganosis reported in 1908, has been global disease, and common China, Japan, Southeast Asian countries. Consumption raw snakes, frogs, fish, or drinking contaminated beverages are sources infections. Human usually manifests subcutaneous fat areas such as abdomen, genitourinary tract, limbs. Breast cases rare, representing less than 2% total Complete...
Hematologic malignancy of the breast is very rare. Here, we report a case relapsed acute myeloid leukemia (AML) presenting as multiple masses. A 77-year-old female visited an outpatient clinic reporting palpable masses in both breasts. She had medical history AML, which showed complete remission after nine cycles chemotherapy. On mammography and ultrasonography, there were correlated with her symptoms accompanied by enlarged lymph nodes. Core needle biopsy immunohistochemistry (IHC) results...
Multiple primary malignancies are defined as the presence of more than one malignant neoplasm with a distinct histology occurring at different sites in same individual. They classified synchronous or metachronous according to diagnostic time interval malignancies. Diagnosis multiple should avoid misclassification from multifocal/multicentric tumors recurrent/metastatic lesions. In malignancies, increase number tumors, frequency rapidly decreases. Here, we report an exceptionally rare case...
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이 연구는 대학도서관 사서들이 업무수행 과정에서 받고 있는 직무스트레스를 보다 정확하게 측정할 수 척도를 개발하고자, 실증연구를 통하여 기존의 국내 외 대표적 직무스트레스 분석하여 종합하고, 질적 연구방법 중 심층면접법을 도입하여 사서가 가지고 특징적인 스트레스 요인을 추적하였다. 또한 두 종합한 척도의 신뢰도와 타당도에 대한 분석을 실행하였다. 그 결과 '동료관계 갈등요인', '상하관계 '업무보상 평가요인', '감정노동 요인', '물리적 환경요인', '고용안정성', '심리적 직무요구요인', '의사결정 및 책임요인', '업무복잡성 '업무경계 그리고 '신체적 직무요구요인' 등 11개 요인, 46개 문항으로 구성된 사서를 위한 척도가 개발되었다. The purpose of this study is to develop a job-stress scale for librarians who work in university libraries. was first conducted by...
SNS 속 '배경 이미지'에 대한 인기가 높아지는 요즘, 사람들은 멋진 셀카를 찍기 위해 디지털 필터를 많이 사용한다. 뿐만 아니라 여러 소셜 플랫폼에 이를 게시하고 공유할 때 통한 편집도 당연시 되고 있다. 필터의 미적 기능은 사용자의 비주얼 이미지를 한층 돋보이도록 꾸미는 데 도움을 주고 있어 자기 가꾸기와 보여주기를 선호하는 대학생들에게 인기를 얻고 다양한 기능과 효과는 이들에게 무료 또는 저비용으로 신비로우면서 색다른 구축하는 준다. 그런데 이러한 필터에 대해 쉽게 접근할 수 있다보니 종류와 기능에 사람들이 어떻게 인식하고 있는지에 대해서는 연구결과가 많지 않다. 사용자들이 더욱 필터 상품들을 기대하고 있지만 관련 연구들은 미비한 상태였다. 따라서 주로 사용하는 대학생을 중심으로 왜 셀카 사진을 찍을 사용하고, 어떤 사용하고자 하는지, 기대감이 있는지 등 그들의 인식 유형과 특성에 조사와 연구를 수행할 필요가 있다고 본다. 본 연구는 인간의 주관성 연구방법인 Q 방법을...
Purpose The purpose of this study is to analyze the clinical features plantar fascia rupture. Materials and Methods We retrospectively reviewed 312 patients with fasciitis between March 2008 February 2013. investigated age, sex, site, visual analogue scale (VAS), body mass index (BMI), characteristics pain, awareness rupture, duration symptoms. Acute rupture was defined as a that occurred during exercise; chronic degenerative after fasciitis. frequency acute Results Among patients, 38...