Electrical neuromodulation of spinal networks improves the control movement paralyzed limbs after cord injury (SCI). However, potential noninvasive stimulation to facilitate postural trunk during sitting in humans with SCI has not been investigated. We hypothesized that transcutaneous electrical lumbosacral enlargement can improve posture. Eight participants non-progressive at C3-T9, American Spinal Injury Association Impairment Scale (AIS) A or C, performed different motor tasks sitting....

Abstract Macrophages and resident microglia play an import role in the secondary neuroinflammation response following spinal cord injury. Reprogramming of macrophage/microglia polarization is strategy for injury restoration. Low-level laser therapy (LLLT) a noninvasive treatment that has been widely used neurotrauma neurodegenerative diseases. However, influence low-level on remains unknown. The present study applied crush rat model. Using immunofluorescence, flow cytometry, RT-qPCR, western...

Abstract Macrophages play key roles in the secondary injury stage of spinal cord (SCI). M1 macrophages occupy lesion area and secrete high levels inflammatory factors that hinder repair, M2 can neurotrophic promote axonal regeneration. The regulation macrophage secretion after SCI is critical for repair. Low‐level laser therapy (810‐nm) (LLLT) boost functional rehabilitation rats SCI; however, mechanisms remain unclear. To explore this issue, we established an vitro model low‐level...

Purpose: We proposed to investigate the effects of miR-452-3p on proliferation and mobility hepatocellular carcinoma (HCC) cells by targeting cytoplasmic polyadenylation element binding protein 3/estimated glomerular filtration rate (CPEB3/EGFR) axis. Methods: Quantitative real-time polymerase chain reaction (qRT-PCR) was used detect expression in 84 pairs HCC tissues adjacent tissues. Luciferase reporter assay employed examine relationship between CPEB3. Microculture tetrazolium (MTT)...

To explore the impacts of social participation and environment on depression among people with stroke.Cross-sectional survey.Structured interviews in participants' homes.Community-dwelling persons stroke rural areas China ( N = 639).Not applicable.Depression (Hamilton Rating Scale for Depression-6), activity (Chinese version World Health Organization's Disability Assessment Schedule 2.0), environmental barriers (Craig Hospital Inventory Environmental Factors), neurological function (Canadian...

Cardiovascular disease has a high prevalence and mortality rate, which are mainly due to the aging population clustering of modifiable cardiovascular risk factors (CRFs); however, studies on Chinese limited. The study aimed investigate CRFs among elderly provide evidence for overall planning medical resources management. In this cross-sectional study, 41,517 participants aged ≥ 65 years were recruited from January 2020 April 2021 in Yuexiu district, Guangzhou city, China. Sociodemographic...

Background Recent studies have found that heart rate response is impaired in patients with type 2 diabetes. However, it remains unclear how chronotropic competence changes these and which index more closely related to This study aims investigate the diabetes compares association of two different indices Patients methods who underwent cardiopulmonary exercise testing at Chengdu Second People's Hospital from October 2022 2023, we included. Logistic regression was used analyze relationship...

Spinal cord injury (SCI) severely impairs the physical and mental health of patients, decreasing their self-efficacy in coping with daily life quality (QOL). In China, a large gap remains between complex long-term needs SCI patients current community care system. With prevalence mobile terminals, usage apps has potential to fill this by extending qualified medical resources families patients. Our team developed app Together for transitional home-dwelling China.

Dissolved oxygen (DO) concentration is an essential indicator for assessment of river ecosystems. A hydrodynamic and water quality mathematical model coupling one-dimensional two-dimensional models developed in this study. The characteristics study area, flow velocity, temperature, organic contamination are taken as consideration the scenario setting. changing processes DO simulated different scenarios, effects on discussed. Results indicate that: 1) negative relation was present between...

Spinal Cord Independence Measure (SCIM) was an important functional outcome measure specifically designed for spinal cord injury (SCI) patients, with the self-reported version of SCIM (SCIM-SR) published in 2013. This study aims to translate SCIM-SR into Chinese, and investigate validity Chinese among SCI patients. translated a standardized approach, then filled out by sample patients (n=205) within 3 days after admission. Validity analyzed using Rasch analysis principal component analysis....

The study was the first to investigate content and composition along with antioxidant activities of polyphenols in dark tea infusions. effect brewing conditions on total polyphenolic contents (TPC) infusions conducted by response surface methodology (RSM), compounds investigated using ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS), DPPH ABTS assay were used evaluate activity tea. Results showed that at water/tea radio 50 : 1 mL/g,...

Object This study was designed to develop an objective and sensitive spinal cord injury (SCI) characterization protocol based on surface electromyography (EMG) activity. Methods Twenty-four patients at both acute chronic time points post-SCI, as well 4 noninjured volunteers, were assessed using neurophysiological clinical measures of volitional motor function. The EMG amplitude recorded from 15 representative muscles bilaterally during standardized maneuvers a assessment voluntary...

Abstract Aim Evaluate the fully online flipped classroom's effects during pandemic. Design A comparative descriptive study with historical control design. Methods In an internal medicine nursing course, classroom instruction was used 53 undergraduates in 2020. Their final examinations were compared 50 students taught traditional offline methods 2019. Online interactions and students' experiences described. Pass rates both classes over 90% ( Χ 2 = 0.276, p 0.60), but median score 2019 higher...

In karst areas, groundwater is an important water source for drinking and irrigation purposes; however, aquifers are vulnerable recovery from damage difficult. We collected surface (pond river water) (hand-pump well, dug borehole samples in Qingyuan city, China, to determine the major chemicals with primary goals of evaluating geochemical composition, identifying processes governing chemistry, probable sources potential contaminants shallow deep study area. The results revealed marked...

To examine the psychometric properties of International Classification Functioning, Disability and Health (ICF) set for spinal cord injury nursing (ICF-SCIN) using Rasch analysis.A total 140 patients were recruited between December 2013 March 2014 through convenience sampling. Nurses used components body functions (BF), structures (BS), activities participation (AP) ICF-SCIN to rate patients' functioning. analysis was performed RUMM 2030 software.In each component, categories rescored from...

Purpose: To explore a set of International Classification Functioning, Disability and Health (ICF) categories that cover the spinal cord injury (SCI) nursing practice in China through national expert survey. Methods: An internet-based email survey was used. original ICF specifically for SCI has been developed from preliminary studies based on an international perspective. For cultural adaptation China, conducted with Chinese experts to identify were China. The which received more than 80%...

Abstract Aims and Objectives To determine the aspects of excretory dysfunction most influential in determining quality life survivors spinal cord injury. Background Excretory is one common troublesome sequelae Previous studies have shown that it can restrict social participation restriction, cause readmission generally influence substantially. Design A cross‐sectional survey hospital inpatients following STOBE guidelines. Methods convenience sample 101 patients with traumatic or...