A5045418610- Congenital Heart Disease Studies
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Pulmonary Hypertension Research and Treatments
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Coronary Artery Anomalies
- Appendicitis Diagnosis and Management
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Cardiac pacing and defibrillation studies
- Intraperitoneal and Appendiceal Malignancies
- Cardiovascular Health and Disease Prevention
- Mechanical Circulatory Support Devices
- Minimally Invasive Surgical Techniques
- Tracheal and airway disorders
- Cardiovascular and Diving-Related Complications
- Advanced MRI Techniques and Applications
- Cardiac Imaging and Diagnostics
- Acute Kidney Injury Research
- Medical Imaging and Pathology Studies
Guy's and St Thomas' NHS Foundation Trust
2021-2025
Royal Brompton Hospital
2010-2025
Harefield Hospital
2020-2025
Imperial College London
2015-2024
Royal Brompton & Harefield NHS Foundation Trust
2022-2023
Medway NHS Foundation Trust
2023
King's College London
2015-2022
St Thomas' Hospital
2015-2022
Norfolk and Norwich University Hospitals NHS Foundation Trust
2007-2017
Norfolk and Norwich University Hospital
2007-2016
To evaluate the late outcomes of adults (above 35 years) with a Fontan-type circulation, for whom current data on morbidity and mortality are lacking.
Abstract Background and Aims Adults with congenital heart disease who underwent a Fontan palliation are at increased risk of premature death. This study aimed to identify score based on widely available clinical variables the first adult visit facilitate personalized care. Methods A single tertiary centre retrospective included adults circulation during their outpatient visit. Anatomic periprocedural data, clinical, laboratory, echocardiographic parameters visit, mortality or transplantation...
Many adult patients with congenital heart disease (ACHD) are still afflicted by premature death. Previous reports suggested natriuretic peptides may identify ACHD adverse outcome. The study investigated prognostic power of B-type peptide (BNP) across the spectrum in a large contemporary cohort.
In patients with acquired heart failure, hypoalbuminaemia is associated increased risk of death. The prevalence hypoproteinaemia and their relation to outcome in adult congenital disease (ACHD) remains, however, unknown.Data on ACHD who underwent blood testing our centre within the last 14 years were collected. between laboratory, clinical or demographic parameters at baseline mortality was assessed using Cox proportional hazards regression analysis.A total 2886 included. Mean age 33.3...
Previous studies in adult congenital heart disease (CHD) have demonstrated a link between renal dysfunction and mortality. However, the prognostic significance of CHD decompensated failure (HF) remains unclear. We sought to assess association outcomes adults with presenting our centre acute HF 2010 2021. This retrospective analysis focused on dysfunction, pre-existing admission, during after index hospitalization. Chronic kidney (CKD) was defined as an estimated glomerular filtration rate...
Background: Brucellosis is a major public health hazard, especially in tropical and subtropical regions. The disease poses considerable hazard because of its quick transmission the possibility severe sequelae. Objective: This study aims to determine seroepidemiology molecular detection brucellosis among Pakistani women with spontaneous abortion. Methodology: A cross-sectional was conducted different hospitals Lahore over four months. total 165 abortion cases were investigated for using...
Background To date, clinical trials have been underpowered to demonstrate a benefit from ACE inhibitors (ACEis) or angiotensin II receptor blockers (ARBs) in preventing systemic right ventricle (sRV) failure and disease progression patients with transposition of the great arteries (TGA). This observational study aimed estimate effect ACEi ARB on heart (HF) incidence mortality large population an sRV. Methods Data all sRV under active follow-up at two tertiary centres between January 2007...
Less than one-third of adolescents with congenital heart disease (CHD) successfully transition to adult care, missing out on education their cardiac condition, and risking loss follow-up. We assessed the efficacy our clinic patient empowerment identified correlates successful transition.Overall, 592 patients were seen at least once in service between 2015 2022 (age 15.2 ± 1.8 years, 47.5% female). Most (53%) had moderate CHD, followed by simple (27.9%) severe (19.1%) CHD. Learning disability...
Pulse wave velocity (PWV) is a biomarker for the intrinsic stiffness of aortic wall, and has been shown to be predictive cardiovascular events. It can assessed using magnetic resonance (CMR) from delay between phase-contrast flow waveforms at two or more locations in aorta, distance on CMR images those locations. This study aimed investigate impact different measurement methods PWV. We present evaluate an algorithm automated centreline tracking 3D images, compare PWV calculations distances...
Abstract We conducted this study to find out if online learning packages in cardiology enabled users increase their knowledge and skills. also looked at how acceptable found these packages. The journal Heart association with BMJ Learning produced a series of modules on common problems. involved pre-test, number interactive cases post-test. A total 1786 completed modules. Doing the improve score from pre-test post-test by significant amount (p<0.001). Feedback was very positive.
Patients with Tetralogy of Fallot (TOF) and pulmonary insufficiency a dilated right ventricle (RV) may suffer from reduction in left ventricular (LV) performance. It is not clear whether timely valve replacement (PVR) preserves LV mechanics.Ten TOF patients who underwent PVR were identified hospital records, pre- postoperative cardiac magnetic resonance images post-processed semi-automatic tissue tracking software. circumferential strain, time to peak torsion compared before after PVR. A...
A case of Takayasu aortitis associated with sarcoidosis presenting recurrent angina is reported. This association has been called 'Takayasu syndrome', which reflects what likely a shared etiology. Myocardial perfusion abnormalities have recently documented in sarcoidosis, but this clarifies for the first time that syndrome due to small vessel coronary arteritis. Corticosteroids and cytotoxic therapy shown be beneficial all forms related vasculitis. Initiation steroid may provide relief...