A5042850478- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Electrical and Bioimpedance Tomography
- Neonatal Respiratory Health Research
- Sepsis Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Intensive Care Unit Cognitive Disorders
- Mechanical Circulatory Support Devices
- Flow Measurement and Analysis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Colorectal Cancer Screening and Detection
- Cardiac Arrest and Resuscitation
- Phonocardiography and Auscultation Techniques
- Intravenous Infusion Technology and Safety
- Genetic factors in colorectal cancer
- Medical Research and Treatments
- Gastric Cancer Management and Outcomes
- Osteomyelitis and Bone Disorders Research
- Bone and Joint Diseases
- Renal function and acid-base balance
- Bone health and treatments
- Inflammasome and immune disorders
- PARP inhibition in cancer therapy
- Anesthesia and Sedative Agents
- Extracellular vesicles in disease
Peking Union Medical College Hospital
2018-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2025
Academy of Medical Sciences
2024
Wuhan Institute of Technology
2024
Wuhan University of Technology
2023
Dali University
2022
Association of Research Libraries
2020
Weatherford College
2020
Abstract Background Individualized positive end-expiratory pressure (PEEP) by electrical impedance tomography (EIT) has potential interest in the optimization of ventilation distribution acute respiratory distress syndrome (ARDS). The aim study was to determine whether early individualized titration PEEP with EIT improved outcomes patients ARDS. Methods A total 117 ARDS receiving mechanical were randomly assigned group ( n = 61, adjusted based on distribution) or control 56, low PEEP/FiO 2...
Photothermal therapy (PTT) is an effective cancer treatment method. Due to its easy focusing and tunability of the irradiation light, direct accurate local can be performed in a noninvasive manner by PTT. This strategy requires use photothermal agents convert light energy into heat energy, thereby achieving heating triggering biochemical processes kill tumor cells. As key factor PTT, conversion ability directly determines efficacy In addition, generally have imaging (PTI) photoacoustic (PAI)...
SAPHO syndrome is a highly heterogeneous disease with distinct treatment response. We report the largest cohort of and explore its clinical classification special interest in spinal sacroiliac involvement.A total 354 patients were recruited Peking Union Medical College Hospital. The demographic, imaging data collected at baseline. Spinal involvement was determined by co-existence related symptoms evidence lesions spine or joints on either bone scintigraphy, CT MRI.A 197 (55.6%) identified to...
Abstract Background High positive end-expiratory pressures (PEEP) may induce overdistension/recruitment and affect ventilation–perfusion matching (VQMatch) in mechanically ventilated patients. This study aimed to investigate the association between PEEP-induced lung VQMatch by electrical impedance tomography (EIT). Methods The was conducted prospectively on 30 adult patients: 18/30 with ARDS 12/30 high risk for ARDS. EIT measurements were performed at zero (ZEEP) subsequently (12–15 cmH 2 O)...
Abstract Background The aim of this study was to validate whether regional ventilation and perfusion data measured by electrical impedance tomography (EIT) with saline bolus could discriminate three broad acute respiratory failure (ARF) etiologies. Methods Perfusion image generated from EIT-based impedance–time curves caused 10 ml 10% NaCl injection during a hold. Ventilation captured before the breath holding period under regular mechanical ventilation. DeadSpace % , Shunt VQMatch were...
To explore the patterns of osteoarticular involvement in SAPHO syndrome. Baseline clinical characteristics and imaging data 99mTc-MDP whole-body bone scintigraphy (WBBS) were collected from 157 out 164 patients diagnosed with The twelve most frequently involved sites analysed by hierarchical cluster analysis Ward minimum-variance method. Three distinctive identified: spinal type (70 patients, 44.6%), predominantly thoracic, lumbar or sacral vertebral lesions; costal (52 33.1%), lesions...
Abstract Background Postextubation high-flow nasal cannula (HFNC) is used as a support therapy in high-risk patients ICU. This study aimed to determine the effects of HFNC on lung recruitment and overdistension assessed by electrical impedance tomography (EIT). Methods Twenty-four who received within 24 h after extubation were prospectively enrolled this study. EIT was monitor regional ventilation distributions at baseline (conventional oxygen therapy) three flow rate levels (20, 40, 60...
Background: Distinguishing ICU patients with candidaemia can help the precise prescription of antifungal drugs to create personalized guidelines. Previous prediction models have primarily used traditional logistic and had some limitations. In this study, we developed a machine learning algorithm trained predict in new-onset systemic inflammatory response syndrome (SIRS). Methods: This retrospective, observational study clinical information collected between January 2013 December 2017 from...
Patient-ventilator asynchrony (PVA) can result in ventilator-induced lung injury (VILI), prolong mechanical ventilation, and ventilator withdrawal failure. The ability of healthcare providers China to recognize patient-ventilator is unknown. aim our study was evaluate the potential influencing factors correctly identify triggering tertiary hospitals China. This an observational carried out 53 A total 191 were asked finish entry test evaluation sequentially. Entry identified qualified...
Regional ventilation/perfusion (V/Q) mismatch in intrapulmonary shunt dependent regions has always been considered a hallmark of ARDS. However, little is known about the spatial distribution shunt, and clear definition lacking. The aim study was to propose two phenotypes for using electrical impedance tomography (EIT) investigate clinical characteristics outcomes preset phenotypes. A total 76 ARDS patients who received EIT saline contrast examination were included this retrospective study....
This study aimed to compare sodium bicarbonate (NaHCO3) and chloride (NaCl) as contrast agents for regional lung perfusion imaging with electrical impedance tomography in critically ill patients respiratory failure. 15 mL 5% NaHCO3 10 10% NaCl were sequentially administered all the enrolled EIT maps divided into four cross-regions: upper right (UR), left (UL), lower (LR), (LL). A total of 20 pair bolus injections from 16 mechanically ventilated obtained. Compared NaHCO3, caused a larger drop...
Abstract Background The Asia-Pacific Colorectal Screening (APCS) score is effective to screen high-risk groups of advanced colorectal neoplasia (ACN) patients but needs revising and can be combined with the fecal immunochemical test (FIT). This paper aimed improve APCS evaluate its use FIT in stratifying risk ACN. Methods prospective multicenter study enrolled 955 1201 asymptomatic Chinese participants form derivation validation set, respectively. Participants received factor questionnaire,...
Background: Esophageal pressure (Pes) has been used as a surrogate of pleural (Ppl) to titrate positive end-expiratory (PEEP) in acute respiratory distress syndrome (ARDS) patients. The relationship between Pes and PEEP remains undetermined. Methods: A gastric tube with balloon catheter was inserted monitor moderate severe ARDS patients who underwent invasive mechanical ventilation. To assess the response (ΔPes) changes (ΔPEEP), level decreased increased subsequently (with an average change...
Pulmonary endarterectomy (PEA) is the standard treatment for chronic thromboembolic pulmonary hypertension. However, it poses risks of perioperative vascular complications, which can lead to serious clinical outcomes. This study introduces a novel noninvasive and radiation-free imaging tool, electrical impedance tomography (EIT), real-time bedside assessment lung perfusion after PEA. It identifies ventilation-perfusion mismatches arising from postoperative particularly valuable patients with...
Several animal studies have shown that regional lung perfusion could be effectively estimated by the hypertonic saline contrast electrical impedance tomography method. Here, we reported an application of this method to dynamically assess pulmonary defect in a patient with acute massive embolism. A 68‐year‐old man experienced sudden dyspnea and cardiac arrest during out‐of‐bed physical activity on first day after partial mediastinal tumor resection. Acute embolism was suspected due...
Pupil monitoring for neurologic examination has become a regular clinical practice during extracorporeal membrane oxygenation (ECMO) therapy. Sudden dilation of pupils always indicates severe cerebrovascular event. However, bilateral dilated nonreactive secondary to neuromuscular blockade are uncommon and widely ignored in adult acute respiratory distress syndrome (ARDS) patients. This is the first case report caused by rocuronium an ARDS patient receiving ECMO treatment.Bilateral were found...
Defined as the energy applied to respiratory system by ventilator, mechanical power (MP) of ventilation reflects risk ventilation-induced lung injury. This study aims explore relationship between dynamic changes in MP and prognosis critically ill patients.This was a single-centre retrospective cohort study. Patients receiving with acute failure (ARF) > 10 J/min on admission ICU were included. (J/min) calculated 0.098 × minute (L/min) [(peak inspiratory pressure + positive end-expiratory...
Abstract Background Setting positive end-expiratory pressure (PEEP) at around 5 cm H 2 O in the early postoperative period seems a common practice for most patients. It remains unclear if routine application of higher levels PEEP confers any meaningful clinical benefit cardiac surgical The aim this study was to compare moderate versus conventional lower on patient-centered outcomes intensive care unit (ICU). Methods This is single-center retrospective involving patients receiving surgery...